Clinical Trials in Massachusetts

Browse 245 Massachusetts Medical Studies Across 1267 Cities
110 Phase 3 Trial · 9082 Massachusetts Clinics

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Clinical Trials Clinical Trials in Massachusetts

Reviewed by Michael Gill, B. Sc.

Image of Brigham and Women's Hospital in Boston, United States.

Phase-Based Progress Estimates

Care.coach Pilotfor Hematopoietic Cell Transplantation

The goal of this research study is to provide an avatar-based technology during a subject's stay for participants who have been admitted to the hospital for reduced-intensity conditioning (RIC) allogeneic transplant. The intervention received will be the care.coach technology.

Brigham and Women's Hospital (+1 Sites)Gregory Abel, MPH, MD

Image of AVAVA, Inc. in Waltham, United States.

Phase-Based Progress Estimates

Treatment With The MIRIA Laserfor Hypertrophy

This study is being conducted to evaluate the performance and efficacy of the AVAVA MIRIA Laser Skin System treatment on acne scars. Participants will be treated with the MIRIA laser at least 4 times with each treatment spaced 4-6 weeks apart. The improvement of acne scars will be evaluated at 1 month and 3 months with a possibility of 6 months evaluation after the fourth treatment.

AVAVA, Inc.AVAVA, Inc.

Image of Neighborhood Healthcare Institute of Health in Escondido, United States.

Phase-Based Progress Estimates

Tirzepatidefor Overweight

This trial will look at whether tirzepatide can reduce obesity-related health problems and death in adults.

Neighborhood Healthcare Institute of Health (+78 Sites)Call 1-877-CTLILLY (1-877-285-4559 or 1-317-615-4559 Mon - Fri 9 AM - 5 PM Eastern time (UTC/GMT - 5 hours, EST)Eli Lilly and Company

Image of MedStar Georgetown University Hospital in Washington, United States.

Phase-Based Progress Estimates

Teclistamab, Daratumumab SC, Lenalidomide (Tec-DR)for Multiple Myeloma

This trial will compare the effectiveness of two different combinations of drugs for treating patients with multiple myeloma who have received at least one prior therapy.

MedStar Georgetown University Hospital (+20 Sites)Janssen Research & Development, LLC Clinical TrialJanssen Research & Development, LLC

Image of Movement and Applied Imaging Lab, Boston University in Boston, United States.

Phase-Based Progress Estimates

Group TMX (Telehealth Exercise And Mindfulness)for Knee

This is a parallel-arm mixed-methods randomized controlled trial to investigate the feasibility of telehealth delivered mindful exercise vs. usual exercise interventions for people with knee osteoarthritis.

Movement and Applied Imaging Lab, Boston UniversityDeepak Kumar, PT, PhD

Image of Research Site in Nashville, United States.

Phase-Based Progress Estimates

Cohort Bfor Breast Cancer

This study to learn more about olaparib and olaparib plus durvalumab combination therapy and also to better understand the studied disease, breast cancer, and associated health problems. Olaparib is a type of drug called a PARP (poly [adenosine diphosphate-ribose] polymerase) inhibitor. PARP inhibitors can destroy cancer cells that are not good at repairing DNA damage. Olaparib is also approved by US Food and Drug Administration (FDA), European Medicines Agency (EMA) and in other countries for treating women with BRCA-mutated, human epidermal growth factor receptor 2 (HER2)-negative metastatic breast cancer. Durvalumab is a type of anticancer drug called immunotherapy that targets cancer cells by blocking the signal that prevents the immune system from seeing the cancer cell. Your immune system can then attack and kill the cancer cells. Durvalumab is approved by the FDA and the EMA for the treatment of patients with locally advanced non-small cell lung cancer after receiving chemoradiation therapy and extensive-stage small cell lung cancer in combination with chemotherapy. Some parts of this study are experimental, which means that durvalumab and the combination of olaparib and durvalumab are still in the development stage for the treatment of breast cancer, and they are not approved for treatment of breast cancer, except for use in research studies like this.

Research Site (+9 Sites)Anitra Fielding, MBChBAstraZeneca

Image of Novo Nordisk Investigational Site in Pembroke Pines, United States.

Phase-Based Progress Estimates

Semaglutide Jfor Diabetes Mellitus, Type 2

This trial is testing a new way to make the diabetes drug semaglutide, to see if it controls blood sugar better than the current version.

Novo Nordisk Investigational Site (+45 Sites)Clinical Transparency (dept. 2834)Novo Nordisk A/S

Image of Care Access Mobile Site in New London, United States.

Phase-Based Progress Estimates

VLA15for Lyme Disease

Senior-friendly

This trial is being conducted to test the safety and effectiveness of a Lyme disease vaccine.

Senior-friendly

Care Access Mobile Site (+57 Sites)Pfizer CT.gov Call CenterValneva Austria GmbH

Image of Prometheus Biosciences Selected Site in Los Angeles, United States.

Phase-Based Progress Estimates

PRA023 IVfor Diffuse Scleroderma

This trial is testing a new drug to see if it's safe and effective for people with a lung disease called SSc-ILD.

Prometheus Biosciences Selected Site (+9 Sites)Prometheus BiosciencesPrometheus Biosciences, Inc.

Image of Mayo Clinic in Scottsdale, United States.

Phase-Based Progress Estimates

Pitolisantfor Idiopathic Hypersomnia

FDA Approved Drug

This trial will assess the safety and efficacy of pitolisant compared to placebo in treating excessive daytime sleepiness in patients with idiopathic hypersomnia.

FDA Approved Drug

Mayo Clinic (+65 Sites)Harmony Biosciences, LLC

Image of Clinical Research Center of Alabama in Birmingham, United States.

Phase-Based Progress Estimates

AK002for Dermatitis

This trial is testing a new drug to see if it's effective and safe for people with moderate-to-severe eczema that isn't controlled by other treatments.

Clinical Research Center of Alabama (+85 Sites)Craig Paterson, MDAllakos Inc.

Image of Children's Hospital of Orange County in Orange, United States.

Phase-Based Progress Estimates

CD33*CD3 BsAbfor Leukemia, Myeloid, Acute

This trial is testing a new antibody drug to treat relapsed or refractory acute myeloid leukemia in pediatric patients.

Children's Hospital of Orange County (+12 Sites)Jessica Pollard, MDY-mAbs Therapeutics

Image of Bausch Site 001 in Palmetto Bay, United States.

Phase-Based Progress Estimates

Rifaximin SSDfor Hepatic Coma

FDA Approved Drug

This trial is testing whether a drug can help prevent hepatic encephalopathy, a complication of liver cirrhosis, in people who have not had it before.

FDA Approved Drug

Bausch Site 001 (+90 Sites)John LaheyBausch Health Americas, Inc.

Image of Emory Healthcare in Atlanta, United States.

Phase-Based Progress Estimates

Fluvoxaminefor COVID-19

FDA Approved Drug

This trial is testing whether repurposed drugs can help relieve symptoms in people with mild to moderate COVID-19. People will either get the drugs or a placebo, and report any new or worsening symptoms. The trial is mostly remote, but some people may need in-person visits.

FDA Approved Drug

Emory Healthcare (+98 Sites)Susanna Naggie, MD

Image of Pulmonary Associates, PA in Phoenix, United States.

Phase-Based Progress Estimates

Sotaterceptfor PAH

This trial is testing a drug to see if it's safe and effective for treating Pulmonary Arterial Hypertension.

Pulmonary Associates, PA (+21 Sites)Jonathan Lu, MD, PhDAcceleron Pharma Inc.

Image of Columbia University Irving Medical Center in New York, United States.

Phase-Based Progress Estimates

Isatuximabfor Monoclonal Gammopathy of Undetermined Significance

FDA Approved Drug

This trial will test whether isatuximab can help improve kidney function in people with MGRS. Isatuximab is not approved by the FDA to treat MGRS, so this trial is considered 'investigational'.

FDA Approved Drug

Columbia University Irving Medical Center (+2 Sites)Divaya Bhutani, MDGenzyme, a Sanofi Company

Image of City of Hope Comprehensive Cancer Center in Duarte, United States.

Phase-Based Progress Estimates

Radiation Therapyfor Malignant neoplasm of prostate

FDA Approved Drug

This trial is testing two different intensities of hormone therapy and radiation therapy, comparing them to the current standard of care, in order to determine the best treatment plan for patients with high risk prostate cancer.

FDA Approved Drug

City of Hope Comprehensive Cancer Center (+99 Sites)Paul L Nguyen

Image of Ronald Reagan UCLA Medical Center in Santa Monica, United States.

Phase-Based Progress Estimates

ARV-471for Breast Cancer

FDA Approved Drug

This trial will test a new drug, ARV-471, to see if it is safe and effective at treating advanced breast cancer. The trial will also test if the new drug is more effective when used in combination with another drug, palbociclib.

FDA Approved Drug

Ronald Reagan UCLA Medical Center (+19 Sites)Arvinas Inc.

Image of CHI St. Vincent, Arkansas in Little Rock, United States.

Phase-Based Progress Estimates

Antiplatelet Therapyfor Bleeding

This trial is looking at whether adding oral anticoagulation to background antiplatelet therapy is effective and safe in preventing thromboembolic events in patients who develop new-onset atrial fibrillation after isolated coronary artery bypass graft surgery.

CHI St. Vincent, Arkansas (+56 Sites)Annetine C Gelijns, PhD

Image of Total Skin and Beauty Dermatology Center in Birmingham, United States.

Phase-Based Progress Estimates

BMS-986165for Psoriasis

Waitlist Available

This trial will study the long-term safety and effectiveness of the drug Deucravacitinib in people who have previously taken it for psoriasis in a different trial.

Waitlist Available

Total Skin and Beauty Dermatology Center (+53 Sites)Bristol-Myers SquibbBristol-Myers Squibb

Image of H. Lee Moffitt Cancer Center in Tampa, United States.

Phase-Based Progress Estimates

Nivolumabfor Carcinoma, Non-Small-Cell Lung

FDA Approved Drug

This trial is testing if using immunotherapy before and after surgery can prolong event-free survival for people with early stage non-small cell lung cancer.

FDA Approved Drug

H. Lee Moffitt Cancer Center (+15 Sites)Bristol-Myers SquibbBristol-Myers Squibb

Image of Investigational Site Number 8400036 in Birmingham, United States.

Phase-Based Progress Estimates

Hepatitis B Vaccinefor Meningococcal Infections

FDA Approved Drug

This trial is testing whether a new vaccine is non-inferior to the current standard vaccine for infants and toddlers. It is also looking at the antibody response to the new vaccine and comparing it to the current standard.

FDA Approved Drug

Investigational Site Number 8400036 (+97 Sites)Clinical Sciences & OperationsSanofi Pasteur, a Sanofi Company

Image of Katmai Oncology Group in Anchorage, United States.

Phase-Based Progress Estimates

Cabozantinib S-malatefor Argentaffinoma

FDA Approved Drug

This trial compares cabozantinib to placebo in treating neuroendocrine or carcinoid tumors. Cabozantinib is a chemotherapy drug that targets specific tyrosine kinase receptors, which when blocked, may slow tumor growth.

FDA Approved Drug

Katmai Oncology Group (+99 Sites)Jennifer A Chan

Image of University of Alabama at Birmingham Cancer Center in Birmingham, United States.

Phase-Based Progress Estimates

Ipilimumabfor Serous Cystadenocarcinoma

FDA Approved Drug

This trial is studying nivolumab and ipilimumab in treating patients with rare tumors.

FDA Approved Drug

University of Alabama at Birmingham Cancer Center (+99 Sites)Sandip P Patel

Image of Investigative Site in Anniston, United States.

Phase-Based Progress Estimates

VIR-2482 (Dose 1)for influenza A virus

The purpose of this study is to evaluate the efficacy, safety, and tolerability of VIR-2482 compared to placebo in preventing influenza A illness in healthy adults 18 to <65 years of age without pre-existing risk factors for serious complications from influenza infection.

Investigative Site (+47 Sites)Vir Biotechnology, Inc.

25 Massachusetts Clinical Trials Near Me

Top Cities for Massachusetts Clinical Trials

Image of Boston in Massachusetts.

Boston

252Active Trials

Massachusetts General HospitalTop Active Site

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New York

173Active Trials

Memorial Sloan Kettering Cancer CenterTop Active Site