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Behavioral Intervention

Serious Games for Autism (SAGA Trial)

N/A
Waitlist Available
Led By Suzy Scherf
Research Sponsored by Penn State University
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Adolescent scores < 80% correct on online eye gaze screening task
Be younger than 65 years old
Timeline
Screening 3 weeks
Treatment Varies
Follow Up 6 months
Awards & highlights

SAGA Trial Summary

This trial will compare the effects of two games on people's behavior, measuring a range of outcomes from controlled tasks to uncontrolled social interactions.

Who is the study for?
This trial is for adolescents with Autism Spectrum Disorder (ASD) aged 10-18 who have normal vision and hearing (with correction), can use a computer, and are native English speakers. They must score below average on an eye gaze task and meet ASD diagnostic criteria. IQ should be between 70-130, reading at least at a 2nd-grade level. Exclusions include recent seizures or legal inability to consent.Check my eligibility
What is being tested?
The study tests an intervention video game designed to improve social skills in autistic adolescents against a placebo control game. Participants will be randomly assigned to either group and assessed before, after playing the games, and again six months later across various social behaviors.See study design
What are the potential side effects?
Since this trial involves video games as interventions, there may not be direct medical side effects; however, participants could experience eye strain or mental fatigue from prolonged screen time.

SAGA Trial Eligibility Criteria

Inclusion Criteria

You may be eligible if you check “Yes” for the criteria below
Select...
I scored below 80% on an eye tracking test online.

SAGA Trial Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~6 months
This trial's timeline: 3 weeks for screening, Varies for treatment, and 6 months for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.
Primary outcome measures
Autism Behaviors - Social Responsiveness Scale 2nd Edition (SRS-2)
Primary Target Eye Gaze Mechanisms - Performance Accuracy
Primary Target Eye Gaze Mechanisms - Visual Fixation
+1 more
Secondary outcome measures
Face-to-Face Social Interactions - Visual Fixations
Intermediate Face Processing Mechanisms - Face Expression Identification - (CAM)
Intermediate Face Processing Mechanisms - Face Expression Identification - (RMET)
+2 more

SAGA Trial Design

2Treatment groups
Experimental Treatment
Placebo Group
Group I: Intervention Video GameExperimental Treatment1 Intervention
Participants will play the Intervention Video Game for 3 months, 3 times a week for a minimum of 30 minutes each session
Group II: Control Video GamePlacebo Group1 Intervention
Participants will play the Control Video Game for 3 months, 3 times a week for a minimum of 30 minutes each session

Find a Location

Who is running the clinical trial?

Penn State UniversityLead Sponsor
355 Previous Clinical Trials
125,697 Total Patients Enrolled
2 Trials studying Autism Spectrum Disorder
460 Patients Enrolled for Autism Spectrum Disorder
National Institute of Mental Health (NIMH)NIH
2,782 Previous Clinical Trials
2,689,047 Total Patients Enrolled
81 Trials studying Autism Spectrum Disorder
40,292 Patients Enrolled for Autism Spectrum Disorder
Suzy ScherfPrincipal InvestigatorPenn State University

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Is this clinical trial available to minors who are under 20 years old?

"This clinical trial only allows participants aged 10 to 18. There are currently 236 studies that cater specifically for children, with 47 other trials targeting patients over the age of 65."

Answered by AI

What criteria must participants fulfill in order to be eligible for this trial?

"This research seeks 60 eligible participants aged 10 to 18 that have autism, early infantile. Additionally, the following conditions must be met: native English speakers in both parent/caregiver and ASD adolescent; a diagnosis of an Autism Spectrum Disorder (ASD) confirmed through parental reports and clinical interviews; normal vision & hearing with corrective measures available for use if needed; able to competently operate a computer for game play; scores < 80% on online eye gaze screening tests; Full Scale IQ between 70-130 with reading ability at least equivalent to 2nd grade level comprehension abilities; cooperative testing from patient required."

Answered by AI

How many subjects are currently engaged in the examination?

"Affirmative. Clinicaltrials.gov data states that the trial, first posted on December 1st 2019, is actively recruiting for 60 individuals at one medical centre. The most recent edit was made on July 5th 2022."

Answered by AI

What are the expected outcomes from this experiment?

"This clinical trial's primary goal, which will be measured over a 6 month period, is to observe the Primary Target Eye Gaze Mechanisms - Visual Fixation. Secondary outcomes include Intermediate Face Processing Mechanisms - Object Identity (CBMT), Face-to-Face Social Interactions - Visual Fixations and Intermediate Face Processing Mechanisms - Face Expression Identification - (CAM). These objectives are assessed across multiple points in time including pre-intervention, post-intervention and 3 months after intervention through standardized measures such as Cambridge Bike Memory Task (CBMT) or the face portion of the Cambridge Affective Memory task (CAM"

Answered by AI

Is this experiment recruiting new participants?

"Affirmative. According to records on clinicaltrials.gov, this research is presently searching for participants. This scientific trial was initially published on December 1st 2019 and updated most recently in July 5th 2022. 60 individuals are expected to be enrolled at a single location."

Answered by AI

Who else is applying?

What state do they live in?
New York
Pennsylvania
How old are they?
18 - 65
What site did they apply to?
Pennsylvania State University
What portion of applicants met pre-screening criteria?
Met criteria
~11 spots leftby Apr 2025