Seroquel Clinical Trials
Browse 16 Seroquel Medical Studies Across 96 Cities
2 Phase 3 Trial · 120 Seroquel Clinics
Clozapine Armfor Schizophrenia
Quetiapinefor Postpartum Depression
BI 1358894for Major Depressive Disorder
Seltorexantfor Major Depressive Disorder
Quetiapinefor Parkinson's Disease
Aripiprazole Once-Monthlyfor Schizophrenia
Seroquel/Teva-Quetiapinefor Healthy Subjects
Treatmentfor Cocaine Use Disorder
It's also occasionally prescribed as an adjunct treatment for patients with major depressive disorder. However, Seroquel is currently being studied as a potential treatment for several other disorders.
What are Seroquel Clinical Trials?
Seroquel has already been found to benefit patients with schizophrenia and bipolar mania, but its safety and effectiveness in the treatment of teenagers continues to be studied.
Researchers are also still trying to determine whether Seroquel works better alone or in conjunction with Lithium in patients who are diagnosed with Bipolar Disorder and if the medication is truly beneficial for those suffering from Major Depressive Disorder.
Why is Seroquel Being Studied in Clinical Trials?
Seroquel is still being studied in clinical trials to determine if it can be used to effectively treat conditions beyond schizophrenia and if it's a safe option for adolescent patients.
Although Seroquel is already being prescribed off-label for the treatment of Major Depression, it has not yet been found to be an effective treatment for this condition, which is why further studies are needed.
Atypical antipsychotics, such as Seroquel, have been found to help patients with Bipolar Disorder, but it's still unclear as to whether they can work alone or need to be prescribed as a combined treatment.
Additionally, Seroquel is currently being studied as a possible remedy for heavy alcohol consumption. If Seroquel is found to be effective at reducing heavy drinking, it could be a revolutionary treatment for alcoholism.
How Does Seroquel Treatment Work?
Seroquel affects the release of certain neurotransmitters in the brain that regulate thoughts and mood.
Schizophrenia has been associated with overactivity of dopamine in the brain. Seroquel works by inhibiting the release of this neurotransmitter, thereby reducing delusions, hallucinations, and mania.
Seroquel also impacts the release of serotonin, which is the neurotransmitter that regulates mood, which explains its reported effectiveness for the treatment of mood disorders, such as Bipolar Disorder and Major Depressive Disorder.
What are Some of the Breakthrough Clinical trials Involving Seroquel?
The most notable Seroquel breakthrough study is the 2007 published and peer reviewed study on the tolerability and effectiveness of the medication in patients with Schizophrenia.
The study found that most patients experienced a reduction in symptoms of psychosis with far fewer side effects than traditional antipsychotic medications, such as Haldol.
This study was especially important because before the development of atypical antipsychotic medication, patients with schizophrenia were prescribed heavy duty medications with major long-term adverse effects, including Tardive Dyskinesia.
Who are the Key Opinion Leaders on Seroquel Clinical Trials Research?
Although AstraZeneca hasn't published the names of the key opinion leaders in Seroquel research, these leaders have still played a vital role in Seroquel's availability to the public for the treatment of mental disorders.
Several key opinion leaders have openly supported Seroquel being marketed to physicians and the public, which has resulted in more interest in this innovative medication.