Reviewed by Michael Gill, B. Sc.
Image of University of New Mexico Health Sciences Center in Albuquerque, United States.
Phase-Based Progress Estimates
1
Effectiveness
2
Safety

Psilocybinfor Alcohol Dependency

18+
All Sexes
This trial is an open-label pilot study (N = 10) designed to assess the effects of psilocybin in alcohol dependent participants, demonstrate the feasibility of the integrated behavioral/pharmacologic intervention, and provide preliminary outcome and safety data. Participants will receive psilocybin orally in two all-day administration sessions, conducted in a secure outpatient psychiatric setting, in a dose range that has been well-tolerated in recent studies. Psilocybin administration will occur in the context of a behavioral intervention including a total of 12 sessions over 12 weeks, incorporating Motivational Enhancement Therapy (MET (Miller, Zweben et al. 1992; Miller 1995), based on Motivational Interviewing (Miller and Rollnick 2002)) with booster sessions, as well as preparation before and debriefing after the psilocybin administration sessions. The MET will incorporate attention to spirituality as well as drinking behavior as a primary subject of change. Drinking outcomes and changes in several potential mediators of treatment effect, including motivation, self-efficacy, craving, depression, anxiety, and spiritual dimensions of the experience, will be measured during treatment and for 24 weeks after the end of treatment. The investigators hypothesize that drinking will decrease following the psilocybin sessions, and that increases in motivation, self-efficacy, and spirituality (primary contrast 12 weeks vs. baseline) will be observed among study participants.
Phase 2
Waitlist Available
University of New Mexico Health Sciences CenterMichael P Bogenschutz, M.D.
25 Psilocybin Clinical Trials Near Me
Top Hospitals for Psilocybin Clinical Trials
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University of Wisconsin
Madison
3Active Trials
0All Time Trials for Psilocybin
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VA Connecticut Healthcare System
West Haven
3Active Trials
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2016First Psilocybin Trial
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Image of Baltimore in Maryland.
Baltimore
10Active Trials
Sheppard Pratt Health SystemTop Active Site
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West Haven
5Active Trials
VA Connecticut Healthcare SystemTop Active Site
Most Recent Psilocybin Clinical Trials
Clinical Trial
Began Recruiting Date
Phase
11/1/2022
Phase 2 & 3
Top Treatments for Psilocybin Clinical Trials
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4
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1
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Oral Psilocybin
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About The Author

Michael Gill preview

Michael Gill - B. Sc.

First Published: October 28th, 2021

Last Reviewed: October 30th, 2022

Michael Gill holds a Bachelors of Science in Integrated Science and Mathematics from McMaster University. During his degree he devoted considerable time modeling the pharmacodynamics of promising drug candidates. Since then, he has leveraged this knowledge of the investigational new drug ecosystem to help his father navigate clinical trials for multiple myeloma, an experience which prompted him to co-found Power Life Sciences: a company that helps patients access randomized controlled trials.

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