Appendix Cancer Clinical Trials 2022

Browse 67 Appendix Cancer Medical Studies Across 117 Cities

2 Phase 3 Trial · 299 Appendix Cancer Clinics

Reviewed by Michael Gill, B. Sc.
Phase-Based Progress Estimates
1
Effectiveness
2
Safety

Paclitaxelfor Ovary Cancer

Bethesda, MD
18+
All Sexes
Background: Tumors that have spread to the lining of the abdomen from other cancers, such as cancer of the appendix, colon, or ovary, are called peritoneal carcinomatosis. In most cases, outcomes are poor. Researchers want to test a new treatment. Objective: To learn if the combination of oral nilotinib plus paclitaxel given by IV and directly into the abdomen can reduce tumors enough for people to have surgery. Eligibility: Adults aged 18 and older with peritoneal carcinomatosis that is too widespread for surgery. Design: Participants will be screened with: Physical exam Medical history Blood and urine tests Electrocardiogram Laparoscopy. They will get general anesthesia. Small cuts will be made in their abdomen. Tissue and fluid samples will be taken. Surveys about their health CT scans of their torso Participants will have up to 4 more laparoscopies. During the first procedure, a port will be placed under the skin of their abdomen (an IP port). It will be attached to a catheter that is placed in their abdomen. Participants will get treatment in 3-week cycles, for 3 or 6 cycles. They will take nilotinib by mouth twice daily. They will get paclitaxel by IP port (once per cycle) and by IV (twice per cycle). After cycles 3 and 6, they will have a laparoscopy and CT scans. Then they may take nilotinib and get IV paclitaxel for up to 1 year. At study visits, participants will repeat some screening tests. About 6 weeks after treatment ends and then every 3 months for 3 years, participants will have follow-up visits at NIH or with their local doctor.
Phase 2
Recruiting
25 Appendix Cancer Clinical Trials Near Me
New York, NY
Bethesda, MD
Tampa, FL
Orange, CA
More Trial Locations
An interactive map to display trial locations for New York Presbyterian Hospital/Columbia University Irving Medical Center, National Institutes of Health Clinical Center, Moffitt Cancer Center, Chao Family Comprehensive Cancer Center, University of California, Irvine, and 96 more locations.
Most Popular References for Appendix Cancer Clinical Trials
Frequency
Citation
Top Hospitals for Appendix Cancer Clinical Trials
Location
Active Appendix Cancer Clinical Trials
All Time Trials for Appendix Cancer
First Recorded Appendix Cancer Trial
Trials
Dana Farber Cancer Institute, Boston, Massachusetts
7
7
2012
Fred Hutch/University of Washington Cancer Consortium, Seattle, Washington
4
4
2018
Top Cities for Appendix Cancer Clinical Trials
City
Active Appendix Cancer Clinical Trials
Top Active Site for Appendix Cancer Clinical Trials
Trial List
Boston, Massachusetts
16
Dana Farber Cancer Institute
Saint Louis, Missouri
9
Washington University School of Medicine
Seattle, Washington
8
Fred Hutch/University of Washington Cancer Consortium
Most Recent Appendix Cancer Clinical Trials
Phase 3 Appendix Cancer Clinical Trials
Clinical Trial
Began Recruiting Date
Phase
Senior Friendly Appendix Cancer Clinical Trials
Recently Completed Studies with FDA Approved Treatments for Appendix Cancer
Treatment
Year
Mechanism of Action
Sponsor
Active Appendix Cancer Clinical Trials
ONCOS-102
2017
Ludwig Institute for Cancer Research
0
Oxaliplatin
2016
Oxaliplatin
University of Massachusetts, Worcester
3

About The Author

Michael Gill preview

Michael Gill - B. Sc.

First Published: October 31st, 2021

Last Reviewed: August 16th, 2022

Michael Gill holds a Bachelors of Science in Integrated Science and Mathematics from McMaster University. During his degree he devoted considerable time modeling the pharmacodynamics of promising drug candidates. Since then, he has leveraged this knowledge of the investigational new drug ecosystem to help his father navigate clinical trials for multiple myeloma, an experience which prompted him to co-found Power Life Sciences: a company that helps patients access randomized controlled trials.