Magnesium Threonate for Sleep After Joint Replacement
What You Need to Know Before You Apply
What is the purpose of this trial?
The study team is conducting a study to see if Magnesium-L-Threonate (MgT) can help improve how well participants sleep and reduce pain after total joint replacement surgery
Will I have to stop taking my current medications?
The trial excludes participants who are taking medications known to cause significant sedation or insomnia, so you may need to stop those specific medications. The protocol does not specify other medication restrictions.
Is Magnesium-L-Threonate safe for humans?
Magnesium-L-Threonate has been studied for its effects on pain relief and reducing opioid use in advanced cancer patients, and no serious safety concerns were reported. Other forms of magnesium, like magnesium sulfate, have been used in various surgeries without serious adverse effects in adults.12345
How does the drug Magnesium-L-Threonate differ from other treatments for sleep issues after joint replacement?
Magnesium-L-Threonate is unique because it is specifically designed to increase magnesium levels in the brain, which can help regulate sleep by enhancing neurotransmitter activity and brain wave patterns. Unlike other magnesium supplements, it has higher bioavailability, meaning it is more effectively absorbed by the body, potentially offering better support for sleep quality.678910
What data supports the effectiveness of the drug Magnesium-L-Threonate for improving sleep after joint replacement?
Research suggests that magnesium, in general, may be linked to better sleep quality, as seen in studies where higher magnesium intake was associated with reduced daytime sleepiness and improved sleep patterns. However, the specific effects of Magnesium-L-Threonate on sleep after joint replacement are not directly studied, and more research is needed to confirm its effectiveness for this purpose.14568
Who Is on the Research Team?
Victor H Hernandez, MD
Principal Investigator
University of Miami
Are You a Good Fit for This Trial?
This trial is for individuals who have undergone total joint replacement surgery due to osteoarthritis and are experiencing sleep disturbances. Participants should be interested in seeing if Magnesium-L-Threonate can help improve their sleep quality and reduce pain post-surgery.Inclusion Criteria
Exclusion Criteria
Timeline for a Trial Participant
Screening
Participants are screened for eligibility to participate in the trial
Treatment
Participants receive Magnesium L Threonate or placebo for up to 6 weeks postoperatively
Follow-up
Participants are monitored for changes in sleep quality and pain management after treatment
What Are the Treatments Tested in This Trial?
Interventions
- Magnesium-L-Threonate
Find a Clinic Near You
Who Is Running the Clinical Trial?
University of Miami
Lead Sponsor