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Procedure

Laryngoscopy Assessment for Laryngopharyngeal Sensation Disorders

Q: Is the age of sixty years or older accepted in this research endeavor?

According to the trial specifications, only individuals aged 18-85 are eligible for enrollment.

Q: What are the criteria for someone to be eligible for this investigation?

In order to qualify, potential participants must possess globus sensation and fall within the age bracket of 18-85. This clinical trial is currently enrolling 40 patients.

Q: Is recruitment still open for this experiment?

Clinicaltrials.gov displays that this medical trial, which was initially made available on November 1st 2023 and most recently modified on October 5th 2023, is not actively searching for participants right now. Fortunately, there are 132 other trials with open enrollment currently in progress.

N/A

Waitlist Available

Led By Yue Ma, MD

Research Sponsored by University of California, San Francisco

Eligibility Criteria Checklist

Specific guidelines that determine who can or cannot participate in a clinical trial

Must have

Age <=18 years

Individuals without a laryngopharyngeal disorder (health controls) or with a laryngopharyngeal disorder. Laryngopharyngeal disorder includes but is not limited to: presbylarynx, aspiration; spasmodic dysphonia; globus pharynges; vocal fold paralysis; iatrogenic injury to the larynx; muscle tension dysphonia; neurogenic dysphagia; laryngeal sensory neuropathy; and laryngopharyngeal disorders resulting from prior radiation therapy in individuals with a history of head and neck cancer who have completed radiation therapy as primary or adjuvant cancer treatment

Timeline

Screening 3 weeks

Treatment Varies

Follow Up 1 day

Awards & highlights

Study Summary

This trial will study laryngopharyngeal disorders caused by cancer treatment, building on previous research.

Who is the study for?

This trial is for adults who can follow study procedures and understand/sign consent forms. It's open to those with or without laryngopharyngeal disorders, including conditions like voice box muscle issues, swallowing difficulties, and nerve damage. Cancer survivors must have finished radiation therapy but cannot join if they're non-English speakers, their throat structures aren't examinable, have severe vocal cord issues, are still in cancer treatment, or can't tolerate laryngoscopy.Check my eligibility

What is being tested?

The study tests how well the throat works in people with hoarseness and related conditions after cancer treatments. It uses a special scope to look inside the throat (Transnasal Laryngoscopy), a device measuring sensation (Cheung-Bearelly Aesthesiometer), and questionnaires to gather patient-reported outcomes.See study design

What are the potential side effects?

Possible side effects include discomfort from the transnasal laryngoscopy procedure such as gagging or nosebleeds; there may also be temporary soreness or irritation in the throat area.

Eligibility Criteria

Inclusion Criteria

You may be eligible if you check “Yes” for the criteria below

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I am 18 years old or younger.

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I either have no throat disorders or I have a condition affecting my throat or voice.

Timeline

Screening ~ 3 weeks3 visits

Treatment ~ Varies

Follow Up ~ 1 day

Screening ~ 3 weeks

Treatment ~ Varies

Follow Up ~1 day

This trial's timeline: 3 weeks for screening, Varies for treatment, and 1 day for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.

Primary outcome measures

Median scores on the Penetration-Aspiration Scale (PAS)

Percentage of participants with triggered/positive laryngeal adduction response (LAR)

Secondary outcome measures

Median scores on the participant-reported laryngeal sensation (PRLS)

Percentage of participants with visualized laryngopharyngeal responses

Trial Design

1Treatment groups

Experimental Treatment

Group I: Cancer SurvivorsExperimental Treatment3 Interventions

Participants will attend a single 15-30 minute study session during which they will answer questionnaires (5-10 minutes) and undergo laryngopharyngeal sensory testing (10-20 minutes). There will be up to 2 years of medical record follow up after completing the main study.

0 / 2Eligibility criteria met

Find a Location

Who is running the clinical trial?

University of California, San FranciscoLead Sponsor

2,507 Previous Clinical Trials

15,238,500 Total Patients Enrolled

National Spasmodic Dysphonia AssociationUNKNOWN

1 Previous Clinical Trials

13 Total Patients Enrolled

Yue Ma, MDPrincipal InvestigatorUniversity of California, San Francisco

1 Previous Clinical Trials

13 Total Patients Enrolled

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Is the age of sixty years or older accepted in this research endeavor?

"According to the trial specifications, only individuals aged 18-85 are eligible for enrollment."

Answered by AI

What are the criteria for someone to be eligible for this investigation?

"In order to qualify, potential participants must possess globus sensation and fall within the age bracket of 18-85. This clinical trial is currently enrolling 40 patients."

Answered by AI

Is recruitment still open for this experiment?

"Clinicaltrials.gov displays that this medical trial, which was initially made available on November 1st 2023 and most recently modified on October 5th 2023, is not actively searching for participants right now. Fortunately, there are 132 other trials with open enrollment currently in progress."

Answered by AI

Recent research and studies

clinicaltrials.govStudy

Assessment of Laryngopharyngeal Sensation: Cancer Survivor Cohort

2024. "Assessment of Laryngopharyngeal Sensation: Cancer Survivor Cohort". ClinicalTrials.gov. https://clinicaltrials.gov/ct2/show/NCT06078527.

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