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Social Network Intervention for HIV Prevention

Waitlist Available
Led By Oluwaseun Falade-Nwulia, MBBS, MPH
Research Sponsored by Johns Hopkins University
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Aged 18 or older
Be older than 18 years old
Must not have
Individuals lacking the capacity to consent
Screening 3 weeks
Treatment Varies
Follow Up 3 months, 9-months
Awards & highlights


This trial aims to increase HIV testing & PrEP knowledge and uptake of HIV & medication for opioid use disorder in Maryland using a social network intervention.

Who is the study for?
This trial is for adults over 18 in Maryland who use syringe service programs and can recruit at least one drug-using peer. They must speak English, be willing to undergo training, and discuss HIV prevention. People unable to consent are excluded.Check my eligibility
What is being tested?
The study tests if a peer-educator network can increase HIV testing, PrEP knowledge, uptake of HIV services/PrEP, and medication for opioid use disorder among people who inject drugs compared to an overdose education control group.See study design
What are the potential side effects?
Since the intervention involves education and social networking rather than medical treatment, there are no direct side effects from medications or procedures; however, discussing sensitive health topics may cause discomfort.

Eligibility Criteria

Inclusion Criteria

You may be eligible if you check “Yes” for the criteria below
I am 18 years old or older.

Exclusion Criteria

You may be eligible for the trial if you check “No” for criteria below:
I am unable to make medical decisions for myself.


Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~3 months, 9-months
This trial's timeline: 3 weeks for screening, Varies for treatment, and 3 months, 9-months for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.
Primary outcome measures
Proportion of HIV testing for Network Members
Secondary outcome measures
Change in Knowledge of PrEP options
Proportion of HIV negative participants who have used PrEP uptake
Proportion of HIV testing for Index Members
+3 more

Trial Design

2Treatment groups
Experimental Treatment
Active Control
Group I: Peer-educator-based network interventionExperimental Treatment1 Intervention
Indexes randomized to the intervention arm will complete a training program that emphasizes effective communication, frequent HIV testing, and awareness of evidence-based HIV prevention and treatment services. An important innovation to the network intervention will be training indexes to use and distribute HIV self-test kits and naloxone to their network members (NMs).
Group II: Equal-attention controlActive Control1 Intervention
This group will receive training sessions that will be focused on the opioid overdose epidemic and will not include any training to serve as a peer educator.

Find a Location

Who is running the clinical trial?

Johns Hopkins UniversityLead Sponsor
2,285 Previous Clinical Trials
14,842,705 Total Patients Enrolled
3 Trials studying Substance Use
2,238 Patients Enrolled for Substance Use
National Institute on Drug Abuse (NIDA)NIH
2,503 Previous Clinical Trials
2,625,223 Total Patients Enrolled
68 Trials studying Substance Use
37,426 Patients Enrolled for Substance Use
Maryland Department of Health and Mental HygieneOTHER_GOV
7 Previous Clinical Trials
4,589 Total Patients Enrolled
~240 spots leftby Nov 2028