← Back to Search

Outpatient vs Hospital Evaluation for Chest Pain (CARE-CP Trial)

N/A

Recruiting

Led By Simon Mahler, MD, MS

Research Sponsored by Wake Forest University Health Sciences

Eligibility Criteria Checklist

Specific guidelines that determine who can or cannot participate in a clinical trial

Must have

No Patients with ≥ 70% Obstructive Coronary Disease

Age ≥21 years old

Timeline

Screening 3 weeks

Treatment Varies

Follow Up year 1

Awards & highlights

CARE-CP Trial Summary

This trial will study if an outpatient evaluation or hospitalization is best for patients with chest pain at risk for ACS. Patients will be randomized to one of the two in the Emergency Department.

Who is the study for?

This trial is for adults over 21 with chest pain or symptoms suggesting a moderate risk of acute coronary syndrome, but without severe heart conditions like prior heart attacks or major artery blockages. They must have normal troponin levels and no other serious health issues that require hospitalization.Check my eligibility

What is being tested?

The CARE-CP study is testing whether it's better to evaluate patients with acute chest pain through rapid outpatient care or traditional hospitalization. Participants are randomly assigned to one of these two approaches in the emergency department.See study design

What are the potential side effects?

Since this trial compares different evaluation methods rather than medications, side effects aren't the focus here. However, there may be risks associated with unnecessary hospital stays or delayed diagnosis depending on the evaluation method used.

CARE-CP Trial Eligibility Criteria

Inclusion Criteria

You may be eligible if you check “Yes” for the criteria below

Select...

My heart's arteries are not 70% or more blocked.

Select...

I am 21 years old or older.

Select...

I am experiencing chest pain or symptoms similar to a heart attack.

Select...

My heart risk score is moderate, and my ECG doesn't show heart damage.

Select...

I have never had coronary artery disease.

Select...

I have never had a procedure to improve blood flow to my heart.

Select...

I have never had a heart attack.

CARE-CP Trial Timeline

Screening ~ 3 weeks3 visits

Treatment ~ Varies

Follow Up ~ year 1

Screening ~ 3 weeks

Treatment ~ Varies

Follow Up ~year 1

This trial's timeline: 3 weeks for screening, Varies for treatment, and year 1 for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.

Primary outcome measures

Hospital-free days (HFD) at 30-days post-randomization

Secondary outcome measures

Cardiovascular Hospital-free days (HFD) at 1 year post-randomization

Cardiovascular Hospital-free days (HFD) at 30-days post-randomization

Cardiovascular rehospitalizations at 1 year post-randomization

+12 more

CARE-CP Trial Design

2Treatment groups

Experimental Treatment

Group I: Outpatient EvaluationExperimental Treatment1 Intervention

Patients randomized to this arm are discharged and receive outpatient evaluation, or cardiovascular ambulatory rapid evaluation (CARE), focused on medical management for cardiovascular risk factors (e.g. hypertension) within 72 hours of Emergency Department discharge.

Group II: Hospitalization EvaluationExperimental Treatment1 Intervention

Patients randomized to this arm receive evaluation for their symptoms in a hospital ward, observation unit, or emergency department boarding.

0 / 7Eligibility criteria met

Find a Location

Who is running the clinical trial?

Wake Forest University Health SciencesLead Sponsor

1,243 Previous Clinical Trials

1,004,228 Total Patients Enrolled

9 Trials studying Chest Pain

16,908 Patients Enrolled for Chest Pain

Agency for Healthcare Research and Quality (AHRQ)FED

399 Previous Clinical Trials

6,821,846 Total Patients Enrolled

1 Trials studying Chest Pain

700 Patients Enrolled for Chest Pain

Simon Mahler, MD, MSPrincipal InvestigatorWake Forest University Health Sciences

1 Previous Clinical Trials

511 Total Patients Enrolled

1 Trials studying Chest Pain

511 Patients Enrolled for Chest Pain

Media Library

Hospitalization Evaluation Clinical Trial Eligibility Overview. Trial Name: NCT05897632 — N/A

Chest Pain Research Study Groups: Hospitalization Evaluation, Outpatient Evaluation

Chest Pain Clinical Trial 2023: Hospitalization Evaluation Highlights & Side Effects. Trial Name: NCT05897632 — N/A

Hospitalization Evaluation 2023 Treatment Timeline for Medical Study. Trial Name: NCT05897632 — N/A

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Is this experiment presently open to participants?

"The clinical trial is not currently open for recruitment according to data on clinicaltrials.gov, despite having been initially posted on October 1st 2023 and last edited June 1st of the same year. Nevertheless, 32 other studies are presently admitting patients into their trials."

Answered by AI

Recent research and studies

clinicaltrials.govStudy

CARE-CP (Testing a Cardiovascular Ambulatory Rapid Evaluation for Patients With Chest Pain)

2023. "CARE-CP (Testing a Cardiovascular Ambulatory Rapid Evaluation for Patients With Chest Pain)". ClinicalTrials.gov. https://clinicaltrials.gov/ct2/show/NCT05897632.