Transbronchial Microwave Ablation for Lung Cancer

Phase-Based Progress Estimates
1
Effectiveness
1
Safety
Lung CancerTransbronchial Microwave Ablation - Device
Eligibility
18+
All Sexes
What conditions do you have?
Select

Study Summary

This trial is testing a new way to destroy cancer cells in the lungs using microwaves, while using CT imaging to guide the placement of the probe tip. The primary endpoint is whether or not this new method is effective in destroying the cancer cells.

Treatment Effectiveness

Study Objectives

1 Primary · 14 Secondary · Reporting Duration: 12-month visit

12-month visit
Change in EORTC QLQ-C30
Change in EORTC QLQ-LC13
Change in Pulmonary Function Tests (Diffusion Capacity)
Change in Pulmonary Function Tests (Lung Volume)
Change in Pulmonary Function Tests (Spirometry I)
Change in Pulmonary Function Tests (Spirometry II)
Disease (cancer) Specific Survival
Local Tumor Progression
Local Tumor Progression Free Survival
Overall Survival
Progression Free Survival
Repeat Ablation Efficacy Rate
Day 30
Technique Efficacy
During navigation (day 0)
Navigational Success
Immediately post-ablation (day 0)
Technical Success

Trial Safety

Trial Design

1 Treatment Group

Transbronchial Microwave Ablation
1 of 1

Experimental Treatment

145 Total Participants · 1 Treatment Group

Primary Treatment: Transbronchial Microwave Ablation · No Placebo Group · N/A

Transbronchial Microwave Ablation
Device
Experimental Group · 1 Intervention: Transbronchial Microwave Ablation · Intervention Types: Device

Trial Logistics

Trial Timeline

Screening: ~3 weeks
Treatment: Varies
Reporting: 12-month visit

Who is running the clinical trial?

Ethicon, Inc.Lead Sponsor
89 Previous Clinical Trials
59,495 Total Patients Enrolled

Eligibility Criteria

Age 18+ · All Participants · 6 Total Inclusion Criteria

Mark “Yes” if the following statements are true for you:
You are 22 years old or older.
You have no performance status.
You have a primary tumor that is controlled.