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Microwave Ablation

Microwave Ablation for Lung Cancer

N/A
Recruiting
Research Sponsored by Ethicon, Inc.
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Oligometastatic lung tumor(s) planned to be ablated in the outer two-thirds of the lung and not closer than 1cm to the pleura.
Subjects greater or equal to 22 years old
Timeline
Screening 3 weeks
Treatment Varies
Follow Up 12-month visit
Awards & highlights
No Placebo-Only Group

Study Summary

This trial is testing a new way to destroy cancer cells in the lungs using microwaves, while using CT imaging to guide the placement of the probe tip. The primary endpoint is whether or not this new method is effective in destroying the cancer cells.

Who is the study for?
Adults (22+ years) with a few lung cancer spots, good performance status (able to carry out daily activities), and tumors in specific lung areas can join. They must not need continuous ventilator support, have severe lung damage, brain metastases, recent other lung treatments or be on certain blood thinners.Check my eligibility
What is being tested?
The study tests a new way to treat small areas of cancer in the lungs using microwave energy guided by advanced robotic technology and CT scans. The goal is to see how well it works one month after treatment.See study design
What are the potential side effects?
Possible side effects may include discomfort at the procedure site, bleeding, infection risk increase due to probe insertion into the lungs, and potential damage to nearby tissues or organs.

Eligibility Criteria

Inclusion Criteria

You may be eligible if you check “Yes” for the criteria below
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My lung tumor is in the outer part of the lung and not near the lung surface.
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I am 22 years old or older.
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My primary lung cancer is under control, and I have one or more small, spread tumors.
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I can take care of myself and am up and about more than 50% of my waking hours.
Select...
My lung tumor is in the outer part of the lung and not near the lung surface.

Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~12-month visit
This trial's timeline: 3 weeks for screening, Varies for treatment, and 12-month visit for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.
Primary outcome measures
Technique Efficacy
Secondary outcome measures
Change in EORTC QLQ-C30
Change in EORTC QLQ-LC13
Change in Pulmonary Function Tests (Diffusion Capacity)
+11 more

Awards & Highlights

No Placebo-Only Group
All patients enrolled in this study will receive some form of active treatment.

Trial Design

1Treatment groups
Experimental Treatment
Group I: Transbronchial Microwave AblationExperimental Treatment1 Intervention
Transbronchial microwave ablation will be performed using the NEUWAVE FLEX Microwave Ablation System and Accessories on oligometastatic tumors in the peripheral lung, guided by the Auris MONARCH Platform for visualization and access while using cone beam CT (computed tomography) to confirm probe tip placement and final ablation zone.

Find a Location

Who is running the clinical trial?

Ethicon, Inc.Lead Sponsor
91 Previous Clinical Trials
60,283 Total Patients Enrolled

Media Library

Transbronchial Microwave Ablation (Microwave Ablation) Clinical Trial Eligibility Overview. Trial Name: NCT05299606 — N/A
Lung Cancer Research Study Groups: Transbronchial Microwave Ablation
Lung Cancer Clinical Trial 2023: Transbronchial Microwave Ablation Highlights & Side Effects. Trial Name: NCT05299606 — N/A
Transbronchial Microwave Ablation (Microwave Ablation) 2023 Treatment Timeline for Medical Study. Trial Name: NCT05299606 — N/A
Lung Cancer Patient Testimony for trial: Trial Name: NCT05299606 — N/A

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

How many places are currently administering this research project?

"Currently, 10 distinct medical centres are accepting patients into this trial. These locations include Farmington, Pinehurst and Cleveland in addition to other locales. To reduce travel obligations, it is advisable to apply at the closest clinic available."

Answered by AI

How many participants have been admitted to this research initiative?

"This clinical trial mandates the inclusion of 145 qualified patients, who may join from UCONN Health in Farmington, Connecticut or FirstHealth Moore Regional Hospital in Pinehurst, North carolina."

Answered by AI

Is the research team currently seeking volunteers for this trial?

"The study is currently recruiting participants, as attested to on clinicaltrials.gov; it was initially posted on October 24th 2022 and revised most recently on November 4th, 2022."

Answered by AI

Who else is applying?

What state do they live in?
Alabama
What site did they apply to?
MD Anderson
What portion of applicants met pre-screening criteria?
Did not meet criteria
How many prior treatments have patients received?
3+

Why did patients apply to this trial?

Tired of doing chemo therapy that seems to have no end and so far no promising.
PatientReceived 2+ prior treatments
~59 spots leftby Jan 2025