Study Summary
This trialstudies a drug to help children with a rare disorder affecting the brain and spinal cord.
- Neuromyelitis Optica Spectrum Disorders
Treatment Effectiveness
Effectiveness Progress
Study Objectives
2 Primary · 7 Secondary · Reporting Duration: Predose and postdose (at end of infusion) on Day 1, Weeks 2, 10, 18, 26, and 42, and predose on Week 50
Trial Safety
Safety Progress
Side Effects for
Trial Design
1 Treatment Group
Ravulizumab
1 of 1
Experimental Treatment
12 Total Participants · 1 Treatment Group
Primary Treatment: Ravulizumab · No Placebo Group · Phase 2 & 3
Trial Logistics
Trial Timeline
Who is running the clinical trial?
Eligibility Criteria
Age 2 - 17 · All Participants · 7 Total Inclusion Criteria
Mark “Yes” if the following statements are true for you:Frequently Asked Questions
How many test subjects are actively participating in this experiment?
"The clinical trial is enrolling 12 patients between 1 sites." - Anonymous Online Contributor
How can I get involved in this research project?
"This clinical trial is admitting 12 participants, within the ages of 2 and 17 who have neuromyelitis optica. It is important that patients also meet the following criteria: Participants must be anti-AQP4 Ab-positive and have a diagnosis of NMOSD as defined by the 2015 international consensus diagnostic criteria., Complement inhibitor treatment-naïve participants must have had at least 1 attack or relapse in the last 12 months prior to the Screening Period., Expanded Disability Status Scale (EDSS) score ≤ 7., Eculizumab-experienced participants must be clinically stable per Investigator for 30 days and have been" - Anonymous Online Contributor
Are we still looking for participants in this research?
"The study is currently ongoing and actively recruiting patients, as reflected in the clinicaltrials.gov posting from June 23rd, 2022 to November 4th, 2022." - Anonymous Online Contributor
Does this clinical trial have an age limit? If so, what is it?
"This particular study is only enrolling patients aged 2-17, however there are 6 other trials for pediatric patients and 16 clinical trials for elderly patients." - Anonymous Online Contributor