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Adaptive Radiotherapy for Small Cell Lung Cancer (DARTS Trial)
DARTS Trial Summary
This trial is testing a new way to give radiation for lung cancer, which may be better at controlling the cancer and have fewer side effects.
DARTS Trial Eligibility Criteria
Inclusion Criteria
You may be eligible if you check “Yes” for the criteria belowDARTS Trial Timeline
Treatment Details
Study Objectives
Outcome measures can provide a clearer picture of what you can expect from a treatment.Side effects data
From 2014 Phase 4 trial • 45 Patients • NCT02000531DARTS Trial Design
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Who is running the clinical trial?
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- My brain cancer has not been stable even with dexamethasone treatment.I have undergone chemotherapy before.My lung cancer has spread to areas near my chest but not beyond my collarbone lymph nodes.My lung disease can be treated with radiation.I cannot have CT scans with dye due to an allergy or kidney issues.I am eligible for chest radiation therapy, including treatment to the lymph nodes above my collarbone.You are expected to live for less than 3 months.I am currently being treated for a serious infection.I have small cell lung cancer and can't receive combined chemotherapy and radiation.My lung disease cannot be treated with targeted radiotherapy.I have been cancer-free for 5 years, except for skin cancer.I have been newly diagnosed with small cell lung cancer and have not received any treatment.I have had surgery in my chest area before.My lung disease cannot be targeted with radiation.I am a candidate for platinum-based chemotherapy.My cancer is made up of different types of cells.I have had radiotherapy to my brain or chest before.I cannot receive platinum-based chemotherapy.I have small cell lung cancer and can't have chemotherapy and radiation at the same time.I am at least 18 years old.I am able to get out of my bed or chair and move around.Your lung function tests show that you can breathe out a certain amount of air and your lungs can transfer oxygen well.My cancer has spread to more than 3 places outside of my chest.
- Group 1: Dose-escalated adaptive chemoradiotherapy
- No Placebo-Only Group - All patients enrolled in this study will receive some form of active treatment.
- Screening: It may take up to 3 Weeks to process to see if you qualify in this trial.
- Treatment: The duration you will receive the treatment varies.
- Follow Ups: You may be asked to continue sharing information regarding the trial for 6 Months after you stop receiving the treatment.
Frequently Asked Questions
Is the utilization of Chemotherapy authorized by the FDA?
"The safety rating of chemotherapy is 2, as there is currently no clinical evidence demonstrating its efficacy but some data that suggests it might be safe."
Is this experiment available to enrollees at present?
"Affirmative. Clinicaltrials.gov data indicates that this investigation is at present enrolling participants, with a first post date of April 25th 2022 and an update on the same day. The team aims to register 31 individuals from one centre for their research."
What is the currenct capacity for participants in this experiment?
"Indeed, the clinicaltrials.gov page states that this trial is currently recruiting volunteers. The study was made public on April 25th 2022 and has since been subject to regular updates. A total of 31 individuals between 1 sites are needed for full enrolment."
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