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Radiation Therapy

SBRT After Prostatectomy for Prostate Cancer (PLUTO-MPC Trial)

N/A
Recruiting
Led By Dr. Chia-Lin Tseng, MD, FRCPC
Research Sponsored by Sunnybrook Health Sciences Centre
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Histologically confirmed diagnosis of adenocarcinoma of the prostate status post radical prostatectomy
Be older than 18 years old
Timeline
Screening 3 weeks
Treatment Varies
Follow Up 6.5years
Awards & highlights

PLUTO-MPC Trial Summary

This trial will study the safety and effectiveness of using SBRT to treat localized prostate cancer in patients who are also candidates for post-prostatectomy radiation.

Who is the study for?
This trial is for men with prostate cancer who've had surgery to remove the prostate but have rising PSA levels, indicating potential cancer activity. They must not have any visible remaining disease, no spread to lymph nodes or distant areas, and no previous pelvic radiation. Participants should be able to fill out health questionnaires.Check my eligibility
What is being tested?
The study is examining the safety and effectiveness of a targeted form of radiation therapy called SBRT for prostate cancer patients after they've undergone surgery (prostatectomy). The focus is on those with localized cancer and increasing PSA levels post-surgery.See study design
What are the potential side effects?
Potential side effects of SBRT may include urinary issues, bowel problems, fatigue, skin reactions in treated areas, erectile dysfunction, and less commonly inflammation or damage to surrounding organs like the bladder or rectum.

PLUTO-MPC Trial Eligibility Criteria

Inclusion Criteria

You may be eligible if you check “Yes” for the criteria below
Select...
I had surgery to remove my prostate due to adenocarcinoma.

PLUTO-MPC Trial Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~6.5years
This trial's timeline: 3 weeks for screening, Varies for treatment, and 6.5years for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.
Primary outcome measures
Early Adverse Events/toxicities experience by Participants
Secondary outcome measures
Biochemical disease-free survival
Health Utilities using EuroQol- 5 Dimension Questionnaire
Health Utilities using The Patient-Oriented Prostate Utility Scale
+2 more

PLUTO-MPC Trial Design

1Treatment groups
Experimental Treatment
Group I: Men with prostate cancer post-prostatectomyExperimental Treatment1 Intervention
Men with localized prostate cancer who are considered candidates for post-prostatectomy radiation.

Find a Location

Who is running the clinical trial?

Sunnybrook Health Sciences CentreLead Sponsor
656 Previous Clinical Trials
1,550,592 Total Patients Enrolled
34 Trials studying Prostate Cancer
12,608 Patients Enrolled for Prostate Cancer
Royal Victoria Regional Health CentreUNKNOWN
1 Previous Clinical Trials
15 Total Patients Enrolled
Princess Margaret Hospital, CanadaOTHER
119 Previous Clinical Trials
39,029 Total Patients Enrolled
9 Trials studying Prostate Cancer
9,886 Patients Enrolled for Prostate Cancer

Media Library

SBRT (Radiation Therapy) Clinical Trial Eligibility Overview. Trial Name: NCT04848909 — N/A
Prostate Cancer Research Study Groups: Men with prostate cancer post-prostatectomy
Prostate Cancer Clinical Trial 2023: SBRT Highlights & Side Effects. Trial Name: NCT04848909 — N/A
SBRT (Radiation Therapy) 2023 Treatment Timeline for Medical Study. Trial Name: NCT04848909 — N/A

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Are there any vacancies open in this research project for participants?

"Affirmative. On clinicaltrials.gov, the information confirms that this trial is currently recruiting participants. It was initially posted on June 3rd 2021 and revised lastly on October 25th 2022, searching for 30 patients from a single site."

Answered by AI

How many participants are currently involved in this clinical exploration?

"Affirmative. The information hosted on clinicaltrials.gov indicates that this investigation is presently recruiting participants, having been first posted June 3rd 2021 and recently updated October 25th 2022. 30 patients need to be enrolled from a single medical centre for the study's completion."

Answered by AI
~17 spots leftby Dec 2027