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SC-DARIC33 CAR T Cells for Acute Myeloid Leukemia
Study Summary
This trial is testing a new treatment for leukemia that uses the patient's own genetically modified cells.
Eligibility Criteria
Inclusion Criteria
You may be eligible if you check “Yes” for the criteria belowTimeline
Treatment Details
Study Objectives
Outcome measures can provide a clearer picture of what you can expect from a treatment.Trial Design
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Who is running the clinical trial?
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- I have had virotherapy before.My kidney, liver, heart, and lungs are working well.I am currently suffering from a severe infection.I have a cancer diagnosis that is not acute myeloid leukemia.I cannot take rapamycin due to health reasons.I can do most activities but may need help, regardless of my age.I have or had brain or spinal cord disease that needed treatment.My AML shows CD33 and has relapsed or is not responding to treatment.I can undergo apheresis or have enough T cells for treatment production.I am 30 years old or younger, but at least 18.I have active GVHD or was on immunosuppressive therapy for GVHD within the last 4 weeks.My brain or spinal cord leukemia symptoms can't be managed before getting DARIC T cell treatment.I will stop all cancer treatments if the apheresis product for DARIC T cells is not available and recover from any major side effects.
- Group 1: DARIC-33
- No Placebo-Only Group - All patients enrolled in this study will receive some form of active treatment.
- Screening: It may take up to 3 Weeks to process to see if you qualify in this trial.
- Treatment: The duration you will receive the treatment varies.
- Follow Ups: You may be asked to continue sharing information regarding the trial for 6 Months after you stop receiving the treatment.
Frequently Asked Questions
What evidence exists to demonstrate that SC-DARIC33 is safe for people?
"This drug's safety rating is 1, as it has only been through the initial phase of testing with limited evidence to support its efficacy and security."
Are any new participants being added to this study at present?
"Affirmative. Clinicaltrials.gov has data verifying that this trial began recruiting on November 29th 2021 and is still enrolling participants as of September 6th 2022, requiring 18 individuals from a solitary medical centre."
What is the cap on volunteer enrollment in this medical research?
"Affirmative, clinicaltrials.gov states that this trail is still searching for suitable subjects. It was first uploaded on November 29th 2021 and most recently updated September 6th 2022. This research requires 18 individuals to be enrolled from one trial site."
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