LungTalk for Increasing Lung Cancer Screening

Recruiting at 10 trial locations

Overseen By Jamie Ostroff, PhD

Age: 18+

Sex: Female

Trial Phase: Phase < 1

Sponsor: Memorial Sloan Kettering Cancer Center

Disqualifiers: Lung cancer, Recent chest CT

No Placebo Group All trial participants will receive the active study treatment (no placebo)

Approved in 1 Jurisdiction This treatment is already approved in other countries

Compensation: Varies

Number of Visits: Unknown

30 Participants Needed

Trial Summary

What is the purpose of this trial?

This trial aims to use emails and an online tool called LungTalk to educate women who have had a mammogram about lung cancer screening. The goal is to increase their awareness and knowledge using easy-to-understand digital content.

Do I need to stop my current medications for this trial?

The trial information does not specify whether you need to stop taking your current medications.

What data supports the effectiveness of the treatment LungTalk for increasing lung cancer screening?

Research shows that using tools and campaigns to increase awareness and understanding of lung cancer screening can lead to more people engaging in screening. For example, educational materials and decision aids have been shown to help patients understand the benefits and risks of screening, which can encourage them to participate in lung cancer screening. ^{1 2 3 4 5}

How is the LungTalk treatment different from other lung cancer screening methods?

LungTalk is unique because it uses social media to increase awareness and knowledge about lung cancer screening among high-risk individuals, aiming to improve screening uptake through tailored health communication. ^{1 2 6 7 8}

Research Team

Tali Amir, MD

Principal Investigator

Memorial Sloan Kettering Cancer Center

Eligibility Criteria

This trial is for women aged 50-80 who have a history of heavy smoking (at least 20-pack-years), either currently smoke or quit within the last 15 years, and haven't had lung cancer screening before. They must have recently had a mammogram with no signs of breast cancer.

Inclusion Criteria

Lung screening naïve as per self-report

My recent mammogram was negative or showed benign findings.

You have smoked at least one pack of cigarettes every day for 20 years or more, according to what you tell us.

Exclusion Criteria

You have had a chest CT scan in the past year.

I have been diagnosed with lung cancer.

Timeline

Screening

Participants are screened for eligibility to participate in the trial

2-4 weeks

Digital Strategy Implementation

Participants engage with the digital strategy involving email communications and LungTalk to increase awareness about lung cancer screening

6 months

Web-based interactions

Follow-up

Participants are monitored for engagement and effectiveness of the digital strategy

4 weeks

Treatment Details

Interventions

• LungTalk

Trial Overview The study is testing 'LungTalk', a digital tool designed to raise awareness about lung cancer screening through emails and an interactive web-based platform featuring text, audio, video, and animations.

Participant Groups

Group I: Women who have had a mammogram Experimental Treatment 1 Intervention

Participants will consist of eligible women who have had a mammogram

Who Is Running the Clinical Trial?

Memorial Sloan Kettering Cancer Center

Lead Sponsor

Trials

1,998

Recruited

602,000+

Findings from Research

A randomized trial involving 298 Maryland Tobacco Quitline callers showed that providing lung cancer screening (LCS) education through print materials led to higher engagement (75% read the materials) compared to web-based materials (61.6%).

Despite similar rates of scheduling or completing LCS between the two groups (around 43%), the study highlights that offering educational materials in preferred formats (print or web) can enhance awareness and potentially increase screening rates among eligible individuals.

NCBI (Pubmed)

pubmed.ncbi.nlm.nih.gov

The tobacco quitline setting as a teachable moment: The Educating Quitline Users About Lung (EQUAL) cancer screening randomized trial. Webster, M., Whealan, J., Williams, RM., et al.[2023]

A focus group study involving 54 participants from Appalachian Kentucky revealed that most individuals were previously unaware of lung cancer screening with low-dose computed tomography (LDCT), highlighting the need for effective awareness campaigns.

Participants emphasized the importance of messaging that includes personal testimonies, hope, and the benefits of early detection, suggesting that communication from trusted healthcare providers is crucial for promoting lung cancer screening.

NCBI (Pubmed)

pubmed.ncbi.nlm.nih.gov

Identifying Community Perspectives for a Lung Cancer Screening Awareness Campaign in Appalachia Kentucky: The Terminate Lung Cancer (TLC) Study. Cardarelli, R., Roper, KL., Cardarelli, K., et al.[2018]

The Risk-Based NLST Outcomes Tool (RNOT) helps individuals understand their personalized risk of lung cancer diagnosis and death, which can aid in making informed decisions about screening.

Participants in the study found the RNOT useful for screening decisions, although they expressed confusion about risk changes and indicated that there was no level of false-positive risk that would deter them from screening.

NCBI (Pubmed)

pubmed.ncbi.nlm.nih.gov

Patient Perspectives on the Risk-Based NLST Outcomes Tool for Lung Cancer Screening. Roberts, MC., Seaman, EL., Klein, WMP., et al.[2022]

A single-page, paper-based encounter decision aid (EDA) used during shared decision-making visits for lung cancer screening significantly reduced patient decisional conflict, as indicated by a drop in the Decisional Conflict Scale score from 35.0 to 0.2 (p < 0.001).

While 28% of patients understood the mortality benefit of lung cancer screening after the visit, a much higher percentage (82%) grasped the frequency of abnormal screening results, highlighting the need for improved patient education on the mortality benefits of screening.

NCBI (Pubmed)

pubmed.ncbi.nlm.nih.gov

Pilot Study of an Encounter Decision Aid for Lung Cancer Screening. Ito Fukunaga, M., Balwan, A., Janis, JA., et al.[2023]

The National Lung Screening Trial found that annual low-dose CT scans can reduce lung cancer-specific mortality by 20% in older heavy smokers, highlighting the potential effectiveness of lung cancer screening.

To maximize the benefits of lung cancer screening, ongoing research is essential for improving risk assessment, patient communication, and management of detected abnormalities, ensuring that screening programs are implemented responsibly.

NCBI (Pubmed)

pubmed.ncbi.nlm.nih.gov

Lung cancer screening. Arenberg, D.[2015]

A randomized controlled trial is being conducted to evaluate the effectiveness of a social media-based intervention called LungTalk, aimed at increasing awareness and knowledge about lung cancer screening among high-risk individuals.

The study addresses the low uptake of lung cancer screening despite evidence from the National Lung Screening Trial showing that low-dose computed tomography can reduce lung cancer mortality, highlighting the potential of social media to reach underserved populations.

NCBI (Pubmed)

pubmed.ncbi.nlm.nih.gov

Leveraging social media to increase lung cancer screening awareness, knowledge and uptake among high-risk populations (The INSPIRE-Lung Study): Study protocol of design and methods of a community-based randomized controlled trial. Lisa, CB., Banerjee, SC., Ostroff, JS., et al.[2023]

Tobacco Treatment Specialists (TTSs) currently lack sufficient knowledge about lung cancer screening (LCS) guidelines, which limits their ability to promote screening among patients, despite recognizing its importance.

There is a significant opportunity to enhance LCS awareness through TTSs, who are willing to incorporate LCS education into their practices, indicating a need for targeted training to improve their effectiveness in this area.

NCBI (Pubmed)

pubmed.ncbi.nlm.nih.gov

Tobacco treatment specialists' knowledge, attitudes and beliefs about lung cancer screening: Potential piece of the puzzle for increasing lung cancer screening awareness. Carter-Bawa, L., Kotsen, C., Schofield, E., et al.[2023]

In a study of 404 patients undergoing lung cancer screening, 26.7-38.0% were found to have inadequate or marginal health literacy, indicating a significant barrier to understanding screening processes.

The readability of online educational materials about lung cancer screening averaged a grade level of 10.6, which is much higher than the recommended 6th grade level, suggesting that these materials may not be accessible to many patients.

NCBI (Pubmed)

pubmed.ncbi.nlm.nih.gov

Lung cancer screening: assessment of health literacy and readability of online educational resources. Haas, K., Brillante, C., Sharp, L., et al.[2019]

References

1. England pubmed.ncbi.nlm.nih.gov

The tobacco quitline setting as a teachable moment: The Educating Quitline Users About Lung (EQUAL) cancer screening randomized trial. [2023]

2. England pubmed.ncbi.nlm.nih.gov

Identifying Community Perspectives for a Lung Cancer Screening Awareness Campaign in Appalachia Kentucky: The Terminate Lung Cancer (TLC) Study. [2018]

3. England pubmed.ncbi.nlm.nih.gov

Patient Perspectives on the Risk-Based NLST Outcomes Tool for Lung Cancer Screening. [2022]

4. England pubmed.ncbi.nlm.nih.gov

Pilot Study of an Encounter Decision Aid for Lung Cancer Screening. [2023]

5. United States pubmed.ncbi.nlm.nih.gov

Lung cancer screening. [2015]

6. United States pubmed.ncbi.nlm.nih.gov

Leveraging social media to increase lung cancer screening awareness, knowledge and uptake among high-risk populations (The INSPIRE-Lung Study): Study protocol of design and methods of a community-based randomized controlled trial. [2023]

7. Ireland pubmed.ncbi.nlm.nih.gov

Tobacco treatment specialists' knowledge, attitudes and beliefs about lung cancer screening: Potential piece of the puzzle for increasing lung cancer screening awareness. [2023]

8. England pubmed.ncbi.nlm.nih.gov

Lung cancer screening: assessment of health literacy and readability of online educational resources. [2019]