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Silica 12CH for Silicosis (HOHM Trial)

Phase < 1
Waitlist Available
Led By Alastair C Gray, PhD
Research Sponsored by HOHM Foundation
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Must be at least 18 years old
Must have a clinical diagnosis of silicosis
Timeline
Screening 3 weeks
Treatment Varies
Follow Up one year
Awards & highlights

HOHM Trial Summary

This trial will investigate complementary treatments for those with Silicosis, a severe, incurable disease. Palliative care is currently all that's available. Research into better treatments is urgently needed.

Who is the study for?
This trial is for adults over 18 in Sao Thome das Letras, Brazil, who have been clinically diagnosed with Silicosis from quartzite mining and are under conventional medical care. It excludes those with Tuberculosis, not suffering from Silicosis, under legal incapacity or too infirm for regular monitoring.Check my eligibility
What is being tested?
The study tests the use of a homeopathic remedy called Silica 12CH to alleviate symptoms of Silicosis—a severe lung disease without a cure—in miners. The aim is to explore complementary treatments alongside existing palliative care.See study design
What are the potential side effects?
Since this trial involves a homeopathic intervention (Silica 12CH), side effects may be minimal or non-existent compared to conventional drugs; however, specific side effect profiles are not provided.

HOHM Trial Eligibility Criteria

Inclusion Criteria

You may be eligible if you check “Yes” for the criteria below
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I am 18 years old or older.
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I have been diagnosed with silicosis.

HOHM Trial Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~one year
This trial's timeline: 3 weeks for screening, Varies for treatment, and one year for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.
Primary outcome measures
Changes in pulmonary health of individuals with Silicosis as assessed by symptoms '1' and '2' using the Measure Yourself Concerns and Wellbeing (MYCaW validated) wellness measurement instrument. 0 = As good as it can be. 6 = As bad as it can be
Secondary outcome measures
Changes in pulmonary health of individuals with Silicosis as assessed by overall wellness scores using the Measure Yourself Concerns and Wellbeing (MYCaW validated) wellness measurement instrument. 0 = As good as it can be. 6 = As bad as it can be.

HOHM Trial Design

1Treatment groups
Experimental Treatment
Group I: Intervention GroupExperimental Treatment1 Intervention
Participants have Silicosis and wish to be included in the intervention group

Find a Location

Who is running the clinical trial?

HOHM FoundationLead Sponsor
Alastair C Gray, PhDPrincipal InvestigatorHOHM Foundation

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Are adults of legal age being included in this medical experiment?

"This medical research is open to adults aged 18 and over, yet below 65 years old."

Answered by AI

Are there any vacancies available for participants in this clinical trial?

"clinicaltrials.gov confirms that recruitment for this specific medical investigation, which was originally posted on November 1st 2023, has closed. However, 3 other trials are actively recruiting at the time of writing."

Answered by AI

Is there a way for me to participate in this experiment?

"In order to take part in this trial, participants must possess silicosis and be between the ages of 18-65. At present, 100 individuals are being sought to contribute to the research."

Answered by AI
~67 spots leftby Mar 2025