Dressings for Hidradenitis Suppurativa

CJ
FR
Overseen ByFranklin R Blum, BS
Age: Any Age
Sex: Any
Trial Phase: Academic
Sponsor: University of North Carolina, Chapel Hill
No Placebo GroupAll trial participants will receive the active study treatment (no placebo)

What You Need to Know Before You Apply

What is the purpose of this trial?

This trial explores better ways to care for wounds after surgery for hidradenitis suppurativa (HS), a severe skin condition that causes painful lumps and abscesses. Researchers are comparing two types of bandages: traditional wet-to-dry dressings and petrolatum with non-stick gauze, to determine which one promotes better healing and causes less pain. The trial is open to those who have had surgery for HS and can manage their own wound care or have someone to assist. The goal is to identify a more effective and comfortable bandaging technique that could also benefit other surgical patients. As an unphased trial, this study allows participants to contribute to innovative wound care solutions that could enhance comfort and healing for many.

Will I have to stop taking my current medications?

The trial information does not specify whether you need to stop taking your current medications. It focuses on wound care after surgery for hidradenitis suppurativa.

What prior data suggests that these bandaging techniques are safe for postoperative wound care?

Research shows that using petrolatum with non-stick gauze is generally safe. Safety reports indicate that this type of dressing poses no major risks and can be discarded like regular trash, suggesting it is usually well-tolerated by patients.

Specific safety information for wet-to-dry dressings is not available, but they are commonly used and are a standard method in wound care. This suggests they are generally safe, though they might cause some discomfort during changes.

In summary, both petrolatum with non-stick gauze and wet-to-dry dressings appear safe for use, based on available information.12345

Why are researchers excited about this trial?

Researchers are excited about these treatments because they explore different approaches to post-surgical care for hidradenitis suppurativa, a challenging skin condition. The petrolatum with non-stick gauze offers a gentler alternative to the traditional wet-to-dry dressings, which can cause discomfort and disturb healing tissue during changes. By reducing irritation and promoting a more comfortable healing environment, petrolatum dressings might improve patient satisfaction and recovery outcomes. While wet-to-dry dressings are the standard of care, this trial seeks to discover if the petrolatum method could be a more effective and less painful option.

What evidence suggests that these bandaging techniques could be effective for hidradenitis suppurativa?

Research has shown that petrolatum with non-stick gauze, which participants in this trial may receive, can help wounds heal faster than traditional methods. This dressing keeps wounds moist, which is crucial for healing. On average, wounds heal about five days quicker with this dressing compared to others. It also tends to cause less pain and requires fewer changes. These benefits make petrolatum with non-stick gauze a promising choice for post-surgery wound care in patients with hidradenitis suppurativa (HS). Meanwhile, another group in this trial will receive standard of care wet-to-dry dressings, serving as the active comparator.56789

Who Is on the Research Team?

CJ

Christopher J Sayed, MD

Principal Investigator

University of North Carolina, Chapel Hill

FR

Franklin R Blum, BS

Principal Investigator

University of North Carolina, Chapel Hill

Are You a Good Fit for This Trial?

Inclusion Criteria

Male & females > or = 16 years of age
Patient must be capable of performing either of the recommended wound care regimens on their own or have someone available to consistently assist with wound care.
Must be able to provide adequate informed consent for themselves
See 1 more

Exclusion Criteria

You cannot participate if you have a preference for a specific type of bandage.
Patients with surgically closed wounds (sutures, staples)
You have had trouble using wet-to-dry or petrolatum and non-stick bandages before.

Timeline for a Trial Participant

Screening

Participants are screened for eligibility to participate in the trial

2-4 weeks

Treatment

Participants receive either wet-to-dry dressings or petrolatum with non-stick bandaging post-surgery

6 weeks
Visits at 1, 2, 4, and 6 weeks post-surgery

Follow-up

Participants are monitored for wound healing and quality of life outcomes

4 weeks

What Are the Treatments Tested in This Trial?

Interventions

  • Petrolatum with Non-Stick Gauze
  • Wet-to-Dry Dressings
How Is the Trial Designed?
2Treatment groups
Experimental Treatment
Active Control
Group I: Petrolatum with Non-Stick GauzeExperimental Treatment1 Intervention
Group II: Wet-to-dry DressingsActive Control1 Intervention

Find a Clinic Near You

Who Is Running the Clinical Trial?

University of North Carolina, Chapel Hill

Lead Sponsor

Trials
1,588
Recruited
4,364,000+

National Center for Advancing Translational Sciences (NCATS)

Collaborator

Trials
394
Recruited
404,000+

Citations

Wet-to-dry vs Petrolatum & Non-stick Dressings After ...Analyzing the efficacy of petrolatum with non-stick bandaging at resolving. HS postoperative wounds and decreasing pain could help guide ...
A Systematic Review and Meta‐Analysis - PubMed Central - NIHRegarding outcomes, the TTH analysis, encompassing 16 trials with 1129 patients, indicated a higher odds of faster mean wound healing rate (odds ...
A Systematic Review and Meta-Analysis of Clinical ...The results revealed that on average the wound healing time of the hydrogel dressings group was shortened by 5.04 days as compared with the control group and ...
Moist dressings in the treatment of pressure injuriesCompared with biological wound dressings, sterile gauze had a lower healing [RR = 0.62, 95%CI (0.43, 0.90)]. There was no statistical difference between other ...
Overview: Petrolatum Impregnated Gauze Wound DressingsPetrolatum gauze by virtue of its limited pore size prevents rapid evaporation from the wound and also prevents absorption by the secondary ...
Modern Wound Dressings: Hydrogel Dressings - PMCHydrogels, unlike other types of modern WDs (foam, films, hydrocolloids), have positive degradation properties that makes them the perfect choice in ...
SAFETY DATA SHEET PETROLATUM DRESSINGThis product, in final form, is a petrolatum gauze dressing, and is not expected to present a spill or release hazard. Environmental precautions: No ...
SAFETY DATA SHEET (SDS)No hazard. The product can be disposed of according to relevant national or local regulations pertaining to the disposal on non-hazardous waste.
Wound Dressings and Comparative Effectiveness Data - PMCRecent studies have shown that semiocclusive dressings do not lead to a reduction in costs and wound healing time compared with gauze dressings for surgical ...
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