assessment of microvascular function for Prophylaxis of Preeclampsia

University of Iowa, Iowa City, IA
Prophylaxis of Preeclampsia+1 More ConditionsAcetylcholine - Drug
18 - 50
What conditions do you have?

Study Summary

This trial seeks to determine whether taking low dose aspirin (LDA) can reduce long-term risk of cardiovascular disease in women who had preeclampsia during pregnancy.

Eligible Conditions
  • Prophylaxis of Preeclampsia
  • Microvascular Function

Treatment Effectiveness

Study Objectives

2 Primary · 0 Secondary · Reporting Duration: at the study visit, an average of 4 hours

Hour 4
microvascular endothelial function
microvascular endothelin-1-mediated constriction

Trial Safety

Awards & Highlights

No Placebo Group
All patients enrolled in this trial will receive the new treatment.

Trial Design

1 Treatment Group

assessment of microvascular function
1 of 1

Experimental Treatment

60 Total Participants · 1 Treatment Group

Primary Treatment: assessment of microvascular function · No Placebo Group · Phase < 1

assessment of microvascular functionExperimental Group · 2 Interventions: Acetylcholine, Endothelin-1 · Intervention Types: Drug, Drug
First Studied
Drug Approval Stage
How many patients have taken this drug
Completed Phase 2

Trial Logistics

Trial Timeline

Screening: ~3 weeks
Treatment: Varies
Reporting: at the study visit, an average of 4 hours

Who is running the clinical trial?

Anna Stanhewicz, PhDLead Sponsor
2 Previous Clinical Trials
44 Total Patients Enrolled

Eligibility Criteria

Age 18 - 50 · Female Participants · 7 Total Inclusion Criteria

Mark “Yes” if the following statements are true for you:

Frequently Asked Questions

Is it permissible to join this investigation if one is of an advanced age?

"The eligibility criteria for this research mandates that patients must be between 18 years and 50 years of age." - Anonymous Online Contributor

Unverified Answer

Is enrollment in this research endeavor still available?

"The current status of this medical trial, which was initially listed on March 1st 2023, is actively recruiting. As per the latest update from April 24th 2023, it can be found on" - Anonymous Online Contributor

Unverified Answer

How many participants is this study enrolling at present?

"Affirmative. According to the information located on, this study has been recruiting participants since its initial post date of March 1st 2023 and is currently seeking 60 people from one site." - Anonymous Online Contributor

Unverified Answer

Would I meet the criteria to take part in this investigation?

"This clinical trial is enrolling sixty persons aged 18 to 50 with a prior history of preeclampsia. In addition, individuals must meet the following criteria: being eighteen years or older; having had a normal gestation and abstaining from taking low-dose aspirin (LDA) during pregnancy; experiencing skin diseases; using tobacco products; suffering from hepatic or metabolic disorders such as chronic kidney disease (CKD), characterized by an eGFR lower than 60 mL/min/1.73m2s; and currently engaging in daily intake of aspirin within 12 weeks up to five years after delivering their baby." - Anonymous Online Contributor

Unverified Answer
Please Note: These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.