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40 Participants Needed
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"I've been struggling with ADHD and anxiety since I was 9 years old. I'm currently 30. I really don't like how numb the medications make me feel. And especially now, that I've lost my grandma and my aunt 8 days apart, my anxiety has been even worse. So I'm trying to find something new."
"I have dealt with voice and vocal fold issues related to paralysis for over 12 years. This problem has negatively impacted virtually every facet of my life. I am an otherwise healthy 48 year old married father of 3 living. My youngest daughter is 12 and has never heard my real voice. I am now having breathing issues related to the paralysis as well as trouble swallowing some liquids. In my research I have seen some recent trials focused on helping people like me."
"My orthopedist recommended a half replacement of my right knee. I have had both hips replaced. Currently have arthritis in knee, shoulder, and thumb. I want to avoid surgery, and I'm open-minded about trying a trial before using surgery as a last resort."
"I changed my diet in 2020 and I’ve lost 95 pounds from my highest weight (283). I am 5’3”, female, and now 188. I still have a 33 BMI. I've been doing research on alternative approaches to continue my progress, which brought me here to consider clinical trials."
"I've tried several different SSRIs over the past 23 years with no luck. Some of these new treatments seem interesting... haven't tried anything like them before. I really hope that one could work."
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468 Participants Needed
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379 Participants Needed
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236 Participants Needed
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18 Participants Needed
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110 Participants Needed
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50 Participants Needed
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240 Participants Needed
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50 Participants Needed
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250 Participants Needed
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Each trial will compensate patients a different amount, but $50-100 for each visit is a fairly common range for Phase 2–4 trials (Phase 1 trials often pay substantially more). Further, most trials will cover the costs of a travel to-and-from the clinic.
After a researcher reviews your profile, they may choose to invite you in to a screening appointment, where they'll determine if you meet 100% of the eligibility requirements. If you do, you'll be sorted into one of the treatment groups, and receive your study drug. For some trials, there is a chance you'll receive a placebo. Across Social Anxiety trials 30% of clinical trials have a placebo. Typically, you'll be required to check-in with the clinic every month or so. The average trial length for Social Anxiety is 12 months.
Not all studies recruit healthy volunteers: usually, Phase 1 studies do. Participating as a healthy volunteer means you will go to a research facility several times over a few days or weeks to receive a dose of either the test treatment or a "placebo," which is a harmless substance that helps researchers compare results. You will have routine tests during these visits, and you'll be compensated for your time and travel, with the number of appointments and details varying by study.
The phase of a trial reveals what stage the drug is in to get approval for a specific condition. Phase 1 trials are the trials to collect safety data in humans. Phase 2 trials are those where the drug has some data showing safety in humans, but where further human data is needed on drug effectiveness. Phase 3 trials are in the final step before approval. The drug already has data showing both safety and effectiveness. As a general rule, Phase 3 trials are more promising than Phase 2, and Phase 2 trials are more promising than phase 1.
Clinical trials are almost always free to participants, and so do not require insurance. The only exception here are trials focused on cancer, because only a small part of the typical treatment plan is actually experimental. For these cancer trials, participants typically need insurance to cover all the non-experimental components.
Most recently, we added Social Stress Test for Social Anxiety, Online Intervention for Transgender Young Adults' Alcohol Use and Pediatric Palliative Care for Rare Diseases to the Power online platform.
We recognize research clinics with these awards when they are especially responsive to patients who apply through the Power online platform. SuperSite clinics are research sites recognized for a high standard of rapid and thorough follow-up with patient applicants. Meanwhile, Power Preferred clinics are the top 20 across the entire Power platform, recognized for their absolute top patient experience.
The Social Anxiety clinics currently recognized as Power Preferred are: American Medical Research in Chicago, Illinois Interventional Psychiatry of Tampa Bay in Tampa, Florida Precise Research Centers in Flowood, Mississippi Preferred Research Partners, Inc. in Little Rock, Arkansas North Texas Clinical Trials in Fort Worth, Texas Mountain View in Denver, Colorado Red Bird Research in Las Vegas, Nevada Red Bird Research in Las Vegas, Nevada Anderson Clinical Research in Redlands, California Excell Research Inc in Oceanside, California California Neuroscience Research, LLC in Sherman Oaks, California Core Clinical Research in Everett, Washington Sunwise Clinical Research in Walnut Creek, California The Social Anxiety clinics currently recognized as SuperSites are: The Medical Research Network, LLC in New York, New York Magnolia Clinical Research (Site #105) in Cary, North Carolina Neurobehavioral Medicine Group in Bloomfield Hills, Michigan Boston Clinical Trials (Alcanza) in Boston, Massachusetts AMR Baber Research in Naperville, Illinois Accel Research Sites-LKD CRU (Alcanza) in Lakeland, Florida BioBehavioral Research of Austin in Austin, Texas IMA Clinical Research Albuquerque in Albuquerque, New Mexico
Yes—most people can greatly reduce or even “beat” social anxiety once they use the right tools. The best-proven approach is cognitive-behavioural therapy that teaches realistic thinking and gradual practice in feared situations; if symptoms remain severe, adding an SSRI-type medication or combining the two boosts success rates. Start by booking an appointment with a CBT-trained mental-health professional (or a guided online CBT program) and, if needed, discuss medication options with your doctor—evidence shows that following this plan helps the majority of people reclaim their social life.
The 3 C’s drawn from cognitive-behavioural therapy are: Catch the anxious thought as soon as it pops up, Check whether it is completely true or helpful, and Change it to a more balanced statement or calming action. Running through this quick three-step loop interrupts the worry spiral and trains your brain to think in a more realistic, less fearful way. If anxiety keeps disrupting your life, a therapist can guide you in practising the 3 C’s more effectively.
Research shows the strongest link to later social anxiety comes from emotional abuse or neglect—situations where a child is constantly ridiculed, shamed, or ignored—but the risk also rises after chronic bullying, highly critical or over-controlling parenting, and, though less specifically, physical or sexual abuse. These experiences teach the child that people are dangerous and that they themselves don’t measure up, wiring the brain to expect rejection; yet plenty of children with such histories avoid social anxiety when they receive warmth and skilled help early on.
A lasting wish to keep away from others is generally called social withdrawal. It may simply reflect an introverted preference for solitude, but when the avoidance is driven by anxiety, depression, or starts harming work, school, or relationships it can point to conditions such as social-anxiety disorder or depression and is worth discussing with a healthcare professional. People often say “asocial,” “reclusive,” or “solitary” for this pattern—just remember that “antisocial” is different and refers to violating others’ rights, not preferring to be alone.
The “3-3-3 rule” is a fast grounding trick: quietly name three things you can see, notice three sounds you can hear, then move or tense three different body parts (for example, wiggle toes, roll shoulders, stretch fingers). By shifting your senses and muscles to the here-and-now, it interrupts the mental spiral of “What are they thinking about me?” that fuels social anxiety. Use it as an on-the-spot reset, and seek longer-term help (like cognitive-behavioural therapy or medication) if anxiety is often limiting your life.
Social anxiety disorder is classified as an anxiety illness, not a neuro-developmental difference, so it isn’t considered “neurodivergent” in the way autism or ADHD are. Because up to half of autistic or ADHD individuals also meet criteria for social anxiety, the two often travel together, and people may describe their lived experience of both under the neurodivergence umbrella. If you deal with persistent social fear—especially alongside attention, sensory, or communication differences—ask a clinician to screen for both conditions so you can combine targeted therapy/medication for anxiety with neurodivergent-friendly supports and accommodations.
Cognitive restructuring for social anxiety follows a simple cycle: write down the anxious thought, ask Socratic questions (“What evidence do I have? How bad would it really be if it happened?”), and replace the thought with a more balanced view, then test that new belief in a small real-world “experiment” (e.g., speak up in a meeting and watch the recording to see how others actually react). Core tools that make this cycle easier are thought-record sheets, cost–benefit or decatastrophizing columns, evidence-for/against lists, and video or in-vivo experiments; used together and paired with gradual exposure—or with a CBT therapist if anxiety is severe—they consistently shrink the fear of negative evaluation.
The “new” medicine people are talking about is fasedienol (also called PH-94B), a nose-spray form of a neurosteroid that aims to calm the brain’s fear center within minutes; it is still in Phase-3 clinical trials, so doctors can’t prescribe it yet—access is only through research studies listed on ClinicalTrials.gov. Standard treatments like SSRIs (e.g., sertraline, paroxetine) and cognitive-behavioral therapy remain the go-to options, while other experimental drugs (such as BNC210 or MDMA-assisted therapy) are also under investigation. If you’re interested, ask your clinician about trial eligibility and continue proven therapies while the new medications work their way toward possible approval.
“7s anxiety” is not a recognized medical condition; people usually encounter this phrase when someone is talking about the GAD-7 questionnaire, where a score of 7 or higher can flag possible generalized anxiety disorder. If you or someone you know consistently feels excessive worry, restlessness, or physical symptoms (e.g., racing heart, trouble sleeping) that disrupt daily life, consider taking a validated screen like the GAD-7 and follow up with a licensed mental-health professional, as proven treatments such as cognitive-behavioral therapy, relaxation skills, and (when needed) medication can greatly reduce symptoms.