← Back to Search

Neurofeedback for Anxiety Disorders

N/A

Recruiting

Led By Stefanie Russman Block, Ph.D

Research Sponsored by University of Michigan

Eligibility Criteria Checklist

Specific guidelines that determine who can or cannot participate in a clinical trial

Must have

Primary diagnosis of generalized anxiety disorder, social anxiety disorder, panic disorder, or illness anxiety disorder based on structured interview

For females, not currently pregnant or actively trying to become pregnant

Timeline

Screening 3 weeks

Treatment Varies

Follow Up approximately 60 minutes

Awards & highlights

Study Summary

This trial hopes to use brain scans to understand how feedback about our own brain activity can help us better regulate emotions. It may lead to better outcomes from psychotherapy in the future.

Who is the study for?

This trial is for individuals with a primary diagnosis of generalized anxiety disorder, social anxiety disorder, panic disorder, or illness anxiety disorder. Participants must be able to consent and tolerate small spaces without anxiety. They should not be on any psychotropic medication except stable antidepressants or birth control, and cannot be pregnant or trying to conceive. No metal implants that affect MRI.Check my eligibility

What is being tested?

The study tests if real-time fMRI neurofeedback (Veritable-NF) can improve emotion regulation in anxious individuals compared to fake feedback (Sham-NF). It measures changes in brain activity and cognitive reappraisal ability—the skill of altering emotional responses by rethinking situations.See study design

What are the potential side effects?

Since the interventions involve non-invasive fMRI scans with either real or sham neurofeedback, there are minimal side effects expected beyond the usual risks associated with MRIs such as discomfort from lying still and loud noises during scanning.

Eligibility Criteria

Inclusion Criteria

You may be eligible if you check “Yes” for the criteria below

Select...

I have been diagnosed with an anxiety disorder.

Select...

I am not pregnant or trying to conceive.

Timeline

Screening ~ 3 weeks3 visits

Treatment ~ Varies

Follow Up ~ approximately 60 minutes

Screening ~ 3 weeks

Treatment ~ Varies

Follow Up ~approximately 60 minutes

This trial's timeline: 3 weeks for screening, Varies for treatment, and approximately 60 minutes for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.

Primary outcome measures

Change in negative affect ratings of images from International Affective Picture System (IAPS)

Change in prefrontal cortex (PFC) activity (baseline to transfer run) from the reappraise > look contrast on the Emotion Regulation Task (ERT)

Secondary outcome measures

Change in amygdala-PFC functional connectivity (baseline to transfer) from reappraise > look contrast

Trial Design

2Treatment groups

Experimental Treatment

Active Control

Group I: Veritable-NFExperimental Treatment1 Intervention

Group II: Sham-NFActive Control1 Intervention

0 / 2Eligibility criteria met

Find a Location

Who is running the clinical trial?

Brain & Behavior Research FoundationOTHER

61 Previous Clinical Trials

2,783 Total Patients Enrolled

University of MichiganLead Sponsor

1,798 Previous Clinical Trials

6,378,108 Total Patients Enrolled

2 Trials studying Panic Disorder

248 Patients Enrolled for Panic Disorder

Stefanie Russman Block, Ph.DPrincipal InvestigatorUniversity of Michigan

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Is it possible to join this research endeavor?

"Patients suffering from panic disorder between the ages of 18-55 are eligible to participate and approximately 30 individuals will be accepted."

Answered by AI

Does this exploratory research have capacity for new participants?

"Per the clinicaltrials.gov portal, this trial is not currently recruiting participants. The experiment was originally posted on February 1st of 2024 and most recently modified on November 9th 2023. Notwithstanding, there are 708 other ongoing studies that are actively searching for volunteers at present."

Answered by AI