Treatment for Spastic
This study is evaluating whether a surgery which reduces spasticity in children with cerebral palsy may also improve their ability to communicate.
See full descriptionAbout the trial for Spastic
Treatment Groups
This trial involves a single treatment. Treatment is the primary treatment being studied. Participants will all receive the same treatment. There is no placebo group. The treatments being tested are not being studied for commercial purposes.
Eligibility
This trial is for patients born any sex aged 65 and younger. There is one eligibility criterion to participate in this trial as listed below.
Approximate Timelines
Measurement Requirements
This trial is evaluating whether Treatment will improve 4 primary outcomes in patients with Spastic. Measurement will happen over the course of Baseline and 12 months.
Who is running the study
Principal InvestigatorPatient Q & A Section
What are the signs of spastic?
spastic may include jerky, random movements and impaired muscle tone; spastic may be due to some form of injury, or may be the result of a non-central cause. Spastic may be the result of some congenital or acquired disease or condition. Spastic may be exacerbated by injury or surgery; and can be the result of a neurological disorder such as a stroke or head injury. If the cause of spastic is obscure, a careful examination of medical records or a neurological inspection might be warranted. Spastic may cause disability. Spastic may be the result of some congenital, acquired or chronic neurological disorder and may not respond to any therapy. A diagnosis of spastic should be made only after careful examination and medical reasoning.
What are common treatments for spastic?
Spastic PDA may require specific therapy, including Botox, botulinum toxin, and surgery. Spastic PDA is commonly treated through a variety of styles of therapy, including: physical therapy and occupational therapy.
Can spastic be cured?
Spastic muscle relaxation techniques may have an important part in the management of spastic, but it can do little to promote long-term functional improvements. In contrast with functional gains, the possibility of achieving cure is low.
What is spastic?
This disorder, which is the most common form of lower motor neuron deficit, is characterized by hyperexcitability caused by a lesion in the anterior horn of a spinal cord motor neuron. Spasticity varies widely and is often difficult to predict.
How many people get spastic a year in the United States?
About 7,000 new cases of spastic alexia are diagnosed a year in the United States. Spastic alexia is also the most common type of alexia in the United States (3,000 cases diagnosed a year in the United States). Spastic alexia is a type of corticobulbar tract, that affects the motor fibers of the affected side of the lower facial nerve.
What causes spastic?
While the term'spasticity' may reflect a change in muscle tone of the spastic limb, the spasm can appear due to an underlying pathophysiological factor. Most cases of spasticity are associated with neurological disease. The spasm appears to be more likely to occur as a result of stretching. Spasticity is seen following the loss of motor control, possibly as a signal for the recovery of motor control, as the stretch is released as the spastic contraction is released.
How does treatment work?
In terms of the actual treatment given to a patient with spastic diplegics, most patients report that their symptoms improved after treatment. Although patients may report improvement in walking or spasticity, only a very small percentage report improvement in speech. Additionally, most patients report that their functional outcome is better after treatment than before treatment. However, only a small minority report that their spastic diplegic is no longer functional.
What is the average age someone gets spastic?
In a recent study, findings shows that average age of onset of spasticity is 52 yr in men and 67 yr in women, suggesting a greater incidence rate in women. This is consistent with prior reports suggesting a later onset of spasticity relative to other motor neuron diseases such as multiple system atrophy. There may be an imbalance in the production of serotonin between men and women.
Does spastic run in families?
Spasticity appears to be a genetically influenced phenomenon. We found a significant association of affected status and spasticity among families and for a single gene locus. We propose that, in hereditary spastic paraplegia, at least two susceptibility genes must interact at the level of the brain, and we have called this phenomenon spastic run in families.
Have there been other clinical trials involving treatment?
While there are studies to help find the root cause of the disease, no drug has shown effectiveness. However, there are several trials to develop treatments. By using Power, you are able to see all of the promising clinical trials.
What are the latest developments in treatment for therapeutic use?
The advancement in understanding the mechanisms behind the treatments have provided a comprehensive treatment options for those with cerebral palsy and ambulatory patients. There is a growing need for a better understanding of the underlying causes, and a more comprehensive treatment approaches for the majority of the people and the society as a whole.
How serious can spastic be?
The spasticity of tetraplegics can vary significantly from this description, because tetraplegics can vary widely in their motor and somatic function. It is important to ensure that the diagnosis of tetraplegia is correct.