← Back to Search

MRI and advanced MRI sequences for Brain Tumor

N/A

Recruiting

Led By Robert Young, MD

Research Sponsored by Memorial Sloan Kettering Cancer Center

Eligibility Criteria Checklist

Specific guidelines that determine who can or cannot participate in a clinical trial

Must have

Age ≥ 18 years old

Suspected or Histopathologically proven diagnosis of high grade or low glioma or tumor is suspected to harbor an isocitrate dehydrogenase (IDH) mutation

Timeline

Screening 3 weeks

Treatment Varies

Follow Up 2 years

Awards & highlights

Study Summary

This trial is testing whether a new brain imaging technique is safe and effective in people with brain tumors.

Who is the study for?

This trial is for adults over 18 with suspected or confirmed high or low grade gliomas, which are types of brain tumors. They should be candidates for radiation therapy and able to consent to the study. It's not suitable for those allergic to MRI contrast agents, have contraindications to MRI like pacemakers, are pregnant/nursing, can't undergo an MRI due to extreme claustrophobia, or cannot cooperate during the procedure.Check my eligibility

What is being tested?

The study is testing whether advanced MR imaging techniques can more accurately identify high-risk areas in malignant gliomas that might recur after treatment. The goal is also to see if these imaging methods can help design better radiation treatment plans and monitor changes in brain tumors.See study design

What are the potential side effects?

Since this trial involves advanced MR imaging rather than drugs, side effects may include discomfort from lying still during the scan and anxiety or claustrophobia inside the scanner. There's a small risk of an allergic reaction to the gadolinium-based contrast agent used.

Eligibility Criteria

Inclusion Criteria

You may be eligible if you check “Yes” for the criteria below

Select...

I am 18 years old or older.

Select...

My brain tumor is suspected to be serious or has a specific genetic change.

Timeline

Screening ~ 3 weeks3 visits

Treatment ~ Varies

Follow Up ~ 2 years

Screening ~ 3 weeks

Treatment ~ Varies

Follow Up ~2 years

This trial's timeline: 3 weeks for screening, Varies for treatment, and 2 years for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.

Primary outcome measures

To assess the utility of baseline advanced MRI & changes between baseline & follow up advanced MRI in predicting high risk areas that are likely to develop progressive glioma despite chemoradiotherapy.

Secondary outcome measures

To compare radiation therapy simulations in patients with gliomas using conventional and baseline advanced MRI data.

feasibility of 2HG spectroscopy

Trial Design

1Treatment groups

Experimental Treatment

Group I: MRIExperimental Treatment1 Intervention

The advanced MRI studies will be obtained at the time of the routinely scheduled preoperative planning MRI and/or the routinely scheduled pre-RT planning MRI at approximately 3±2 weeks after surgery. The routine sequences obtained for the planning MRI are standard of care. The advanced MRI sequences may or may not be additional as some have already been adopted into the standard of care imaging at MSKCC.

0 / 2Eligibility criteria met

Find a Location

Who is running the clinical trial?

Memorial Sloan Kettering Cancer CenterLead Sponsor

1,934 Previous Clinical Trials

588,675 Total Patients Enrolled

Robert Young, MDPrincipal InvestigatorMemorial Sloan Kettering Cancer Center

4 Previous Clinical Trials

521 Total Patients Enrolled

Media Library

MRI and advanced MRI sequences Clinical Trial Eligibility Overview. Trial Name: NCT00870129 — N/A

MRI and advanced MRI sequences 2023 Treatment Timeline for Medical Study. Trial Name: NCT00870129 — N/A

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Are applicants still being accepted for this clinical research initiative?

"Affirmative, clinicaltrials.gov serves as a source of evidence that this research is actively seeking participants - it was originally announced on March 1st 2009 and last updated on September 1st 2022. The trial requires 135 people to be enrolled from one location."

Answered by AI

What is the participant cap for this clinical trial?

"Affirmative, the online record on clinicaltrials.gov confirms that this medical research is presently looking for participants. The trial was first published on March 1st 2009 and has since been edited as recently as September 1st 2022. It is currently trying to recruit 135 patients from a single site."

Answered by AI

Recent research and studies

clinicaltrials.govStudy

Magnetic Resonance (MR) Imaging to Determine High Risk Areas in Patients With Malignant Gliomas and to Design Potential Radiation Plans and to Examine Metabolite Changes in Gliomas and Other Solid Tumors

2009. "Magnetic Resonance (MR) Imaging to Determine High Risk Areas in Patients With Malignant Gliomas and to Design Potential Radiation Plans and to Examine Metabolite Changes in Gliomas and Other Solid Tumors". ClinicalTrials.gov. https://clinicaltrials.gov/ct2/show/NCT00870129.

All > Aging > Glioma