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Nerve Blocks for Post-Traumatic Headache
Study Summary
This trial is looking at the effect of two invasive procedures, occipital nerve block (ONB) and cervical medial branch block (CMBB), on post-traumatic headaches (PTH).
Eligibility Criteria
Inclusion Criteria
You may be eligible if you check “Yes” for the criteria belowTimeline
Treatment Details
Study Objectives
Outcome measures can provide a clearer picture of what you can expect from a treatment.Trial Design
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Who is running the clinical trial?
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- I have had headaches or neck pain after a head injury in the past year.I have had headaches or neck pain from a head injury in the past year.I am between 14 and 45 years old.I (or my child) can't participate due to not giving consent or being unable to complete the questionnaire.You have serious mental health issues, as decided by a study psychologist after reviewing a standard test.I have tried at least one treatment for my condition without significant improvement.I've tried at least one treatment for my condition without significant improvement.I am between 14 and 45 years old.
- Group 1: Cervical Medial Branch Block
- Group 2: Occipital Nerve Block
- No Placebo-Only Group - All patients enrolled in this study will receive some form of active treatment.
- Pivotal Trial - The final step before approval, pivotal trials feature drugs that have already shown basic safety & efficacy.
- All Individual Drugs Already Approved - Therapies where all constituent drugs have already been approved are likely to have better-understood side effect profiles.
- Screening: It may take up to 3 Weeks to process to see if you qualify in this trial.
- Treatment: The duration you will receive the treatment varies.
- Follow Ups: You may be asked to continue sharing information regarding the trial for 6 Months after you stop receiving the treatment.
Frequently Asked Questions
Will elderly citizens be able to partake in this research?
"The age range for this clinical trial is 14 to 45. If you are either younger or older, there are still many options available as there are 31 studies for patients under 18 and 207 for those over 65."
Are there any other published reports of similar medical trials involving lidocaine and dexamethasone for ONB?
"There are a total of 135 clinical studies underway that are investigating the use of lidocaine and dexamethasone in Occipital Nerve Block (ONB). Out of these, 34 are in Phase 3. The majority of research locations for Occipital Nerve Block (ONB) using lidocaine and dexamethosone are in Calgary, Alberta; however, there are 1,083 total sites running these studies."
Is the ONB procedure that uses lidocaine and dexamethasone currently federally regulated?
"The safety of Occipital Nerve Block (ONB) using lidocaine and dexamethosone has been rigorously tested in Phase 3 clinical trials, so our team rates its safety as a 3."
How does ONB using lidocaine and dexamethosone help patients?
"Although most commonly used to treat cervical syndrome, lidocaine and dexamethasone-based ONB can also help patients with conditions like minor burns, transplantation, and osteoporosis."
How many enrollees are in this clinical trial?
"Yes, according to the website clinicaltrials.gov, this study is still looking for participants. This particular trial was first posted on 2018-01-02, and the listing was updated on 2022-09-21. They are hoping to enroll 63 individuals at 2 different locations."
Who else is applying?
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What portion of applicants met pre-screening criteria?
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