Study Summary
This trial is testing a new technique for delivering chemotherapy directly into the lungs at the time of surgery. The goal is to kill any microscopic cancer cells that are present in the lungs at the time of surgery, while sparing other major organs in the body from the side effects of chemotherapy.
- Soft Tissue Sarcoma
- Bone Sarcoma
- Lung Cancer
Treatment Effectiveness
Phase-Based Effectiveness
Study Objectives
2 Primary · 0 Secondary · Reporting Duration: Up to 2 years
Trial Safety
Phase-Based Safety
Side Effects for
Awards & Highlights
Trial Design
9 Treatment Groups
Doxorubicin 7 mcg/ml - expansion
1 of 9
Doxorubicin 13 mcg/ml
1 of 9
Doxorubicin 11 mcg/ml
1 of 9
Doxorubicin 17 mcg/ml
1 of 9
Doxorubicin 20 mcg/ml
1 of 9
Doxorubicin 9 mcg/ml
1 of 9
Doxorubicin 5 mcg/ml
1 of 9
Doxorubicin 7 mcg/ml
1 of 9
Doxorubicin 15 mcg/ml
1 of 9
Experimental Treatment
17 Total Participants · 9 Treatment Groups
Primary Treatment: Doxorubicin · No Placebo Group · Phase 1
Trial Logistics
Trial Timeline
Who is running the clinical trial?
Eligibility Criteria
Age No minimum age - 64 · All Participants · 2 Total Inclusion Criteria
Mark “Yes” if the following statements are true for you:Frequently Asked Questions
Has the Food and Drug Administration sanctioned Doxorubicin for therapeutic use?
"Due to a lack of data regarding safety and efficacy, our team at Power assigned Doxorubicin an initial score of 1." - Anonymous Online Contributor
Does the age criteria for this clinical experiment encompass those who are octogenarians or older?
"This medical trial is restricted to those ages 0-64. Conversely, 309 trials are currently available for minors and 2680 exist for seniors over the age of 65." - Anonymous Online Contributor
Is registration still available for this investigation?
"Clinicaltrials.gov reveals that this medical trial is not accepting new participants at the moment. The study was initially listed on February 1st 2016 and its page last modified on April 8th 2022. Although this test is closed to enrollment, there are 2863 other studies looking for volunteers presently." - Anonymous Online Contributor
Are there any documented precedents of experiments that use Doxorubicin?
"Currently, 360 clinical trials are being conducted to test the efficacy of Doxorubicin. Of these, 119 are in their final phase and primarily based in New York City; however, there are over 23000 sites gathering data from around the country." - Anonymous Online Contributor
To what demographic is this research project accessible?
"This specific clinical trial is recruiting 11 patients, aged 0 to 64 years old with sarcoma of the bone. As per inclusion criteria, they must have an ECOG score between 0 and 2, 3 or more lesions in their lungs accessible for treatment using IVLP (the remaining ones should be treated by surgery/radiation 4-12 weeks before commencing IVLP), be under 65 years old and present contralateral disease amenable to either radiation therapy or surgical resection." - Anonymous Online Contributor
To what extent is the capacity of this experiment being tested?
"At this time, this trial is not enrolling any additional participants. The study was posted on the 1st of February 2016 and last updated on April 8th 2022. If you are looking for other medical trials, there are presently 2503 studies with sarcoma-related research pursues that require volunteers as well as 360 clinical investigations concerning Doxorubicin which are actively recruiting patients." - Anonymous Online Contributor
What ailments is Doxorubicin primarily employed to address?
"Doxorubicin is commonly used as a form of therapy for lymphoma and Hodgkin's Disease. Additionally, it can be employed to treat conditions such as bronchogenic carcinoma, neuroblastoma (NB), and Sezary Syndrome." - Anonymous Online Contributor
Has a similar clinical trial been conducted in the past?
"Since its first trial in 1997, sponsored by Alfacell and involving 300 patients, doxorubicin has been studied extensively. Subsequently granted Phase 3 approval for use as a drug, 360 different trials are currently active across 1941 cities and 66 countries worldwide." - Anonymous Online Contributor