This trial will test the combination of DFMO and etoposide for subjects with relapsed/refractory neuroblastoma.
1 Primary · 3 Secondary · Reporting Duration: 2 years plus 5 years follow up
Side Effects for
1 Treatment Group
1 of 1
131 Total Participants · 1 Treatment Group
Primary Treatment: Eflornithine · No Placebo Group · Phase 2
Who is running the clinical trial?
Age < 65 · All Participants · 7 Total Inclusion CriteriaMark “Yes” if the following statements are true for you:
Frequently Asked Questions
Is this a pioneering trial for its kind?
"Presently, 11 live clinical trials are taking place for Eflornithine across 699 cities and 12 countries. Cancer Prevention Pharmaceuticals, Inc. initiated the first trial in 2013 with 1340 participants which has since gone through its Phase 3 drug approval stage. In addition to this initial study, 10 other experiments have also been concluded so far." - Anonymous Online Contributor
What is the aggregate number of participants engaging in this research project?
"This clinical trial necessitates 131 participants who meet the inclusion standards. Patients can join in from sites such as Augusta University Health (Augusta, Georgia) and Children's Medical Center (Dallas, Texas)." - Anonymous Online Contributor
Are there still opportunities to join this research endeavor?
"Affirmative. The information posted on clinicaltrials.gov affirms that this medical trial is actively recruiting 131 patients at 23 sites, beginning September 25th 2020 and most recently updated April 20th 2022." - Anonymous Online Contributor
How widely dispersed is the experimental program?
"Augusta University Health in Augusta, Georgia, Children's Medical Center in Dallas, Texas, and the Medical University of South Carolina located in Charleston are some of the 23 research hubs associated with this medical trial." - Anonymous Online Contributor
What prior investigations have been conducted regarding Eflornithine?
"In 2013, the first studies of eflornithine were conducted at Lake Norman Hematology Oncology Specialists-Mooresville. To date, 10 trials have been concluded and there are 11 ongoing clinical tests - primarily located in Augusta, Georgia." - Anonymous Online Contributor
To what extent does Eflornithine pose a risk to individuals?
"Although there is some evidence of Eflornithine's safety, the lack of data concerning efficacy gives this medication a 2 on our team's safety scale." - Anonymous Online Contributor