PEFA VT ablation technique for Ventricular Tachycardia

Kingston Health Sciences Centre, Kingston, Canada
Ventricular TachycardiaPEFA VT ablation technique - Procedure
All Sexes
What conditions do you have?

Study Summary

This trial looked at how well an ICD worked in people with heart disease.

Eligible Conditions
  • Ventricular Tachycardia

Treatment Effectiveness

Phase-Based Effectiveness

1 of 3

Study Objectives

5 Primary · 4 Secondary · Reporting Duration: 3 years

3 years
All-cause mortality
Appropriate ICD shock
Appropriate anti-tachycardia pacing (ATP) from ICD
Escalation and De-escalation of antiarrhythmic medication
Incessant VT
Inducible for ventricular arrhythmia
Number of ventricular arrhythmia events
Treated sustained VT below the detection rate of the ICD
VT storm

Trial Safety

Phase-Based Safety

1 of 3

Awards & Highlights

No Placebo Group
All patients enrolled in this trial will receive the new treatment.

Trial Design

1 Treatment Group

PEFA targeted substrate ablation
1 of 1

Experimental Treatment

40 Total Participants · 1 Treatment Group

Primary Treatment: PEFA VT ablation technique · No Placebo Group · N/A

PEFA targeted substrate ablation
Experimental Group · 1 Intervention: PEFA VT ablation technique · Intervention Types: Procedure

Trial Logistics

Trial Timeline

Screening: ~3 weeks
Treatment: Varies
Reporting: 3 years

Who is running the clinical trial?

Dr. Damian RedfearnLead Sponsor
Damian RedfearnPrincipal InvestigatorKingston Health Sciences Centre
Damian Redfearn, MDPrincipal InvestigatorQueen's University

Eligibility Criteria

Age 18+ · All Participants · 2 Total Inclusion Criteria

Mark “Yes” if the following statements are true for you:
You are a suitable candidate for catheter ablation, which is a standard medical procedure.
You have an implanted device that helps regulate your heart (ICD).

Frequently Asked Questions

What is the primary aim of this investigation?

"The aim of this 3 year clinical trial is to reduce the amount of sustained ventricular tachycardia below a level that cannot be detected by an implantable cardioverter defibrillator (ICD). Secondary objectives include tracking changes in antiarrhythmic drug dosages due to efficacy or side effects, monitoring the total number of arrhythmias events over time, and measuring appropriate ATP from ICDs." - Anonymous Online Contributor

Unverified Answer

How many individuals are eligible for inclusion in this research project?

"Affirmative. According to the database, this experiment is currently open for recruitment and was initially posted on August 13th 2019 . 40 subjects are needed from 3 separate medical sites with the most recent update occurring on August 2nd 2022." - Anonymous Online Contributor

Unverified Answer

Is recruitment for this medical experiment still open?

"Correct. Data hosted on confirms that, as of August 2nd 2022, this medical study is actively seeking candidates for enrollment; the trial was initially posted back in August 2019 and requires 40 participants from 3 distinct sites." - Anonymous Online Contributor

Unverified Answer
Please Note: These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.