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AV-380 for Cachexia
Study Summary
This trial studies an antibody that targets a protein linked to cancer-induced cachexia in metastatic cancer patients.
Eligibility Criteria
Inclusion Criteria
You may be eligible if you check “Yes” for the criteria belowTimeline
Treatment Details
Study Objectives
Outcome measures can provide a clearer picture of what you can expect from a treatment.Trial Design
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Who is running the clinical trial?
Media Library
- I am undergoing first-line chemotherapy for metastatic CRC or pancreatic cancer and have completed at least 2 cycles.Your heart's electrical activity (QT interval) is longer than normal.I am 18 years old or older.I do not have severe allergies or major health issues affecting my organs or mental health.I have lost more than 5% of my weight in the last 6 months, or my BMI is below 20 with any weight loss, or I have muscle loss with any weight loss.My brain metastases have been treated and stable for at least 2 weeks.I have not had a heart attack in the last 3 months.
- Group 1: Cohort 1
- Group 2: Cohort 2
- Group 3: Cohort 3
- Group 4: Cohort 4
- Group 5: Cohort 5
- No Placebo-Only Group - All patients enrolled in this study will receive some form of active treatment.
- Screening: It may take up to 3 Weeks to process to see if you qualify in this trial.
- Treatment: The duration you will receive the treatment varies.
- Follow Ups: You may be asked to continue sharing information regarding the trial for 6 Months after you stop receiving the treatment.
Frequently Asked Questions
Are enrollees presently being welcomed into this trial?
"According to the clinicaltrials.gov website, this experiment is currently searching for participants. The original post was on June 13th of 2023 and has been freshly modified on July 18th of the same year."
Has Cohort 1 satisfied the requirements for federal approval?
"Cohort 1 has only minimal safety data associated with it, so our assessment of its risk profile is a score of one."
How many venues has this examination been administered in?
"Presently, this trial is recruiting participants at 6 medical locations. These include New york Cancer and Blood Specialists in the Bronx, University Hospitals Cleveland Medical Center in Manhattan, and Summit Cancer Centers in Port Jefferson Station; as well as 3 other sites scattered across nation."
How many participants are involved in this medical experiment?
"This trial necessitates 30 suitable candidates to be enrolled. Those who meet the qualifications can access this study from New york Cancer and Blood Specialists in Bronx, NY or University Hospitals Cleveland Medical Center in Cleveland, Ohio."
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