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Low-Dose CT Screening for Lung Cancer (ILST Trial)
N/A
Waitlist Available
Led By Kwun M Fong
Research Sponsored by The University of Queensland
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial Must have
Current or former smokers (defined as one who has stopped smoking for one or more years)
ECOG performance status 0 or 1
Timeline
Screening 3 weeks
Treatment Varies
Follow Up 5 years
Awards & highlights
ILST Trial Summary
This trial will help determine if CT chest scans can help reduce lung cancer deaths by finding the disease early.
Who is the study for?
This trial is for men and women aged 55-80 who are current or former smokers with a significant history of smoking (at least 30 pack-years) and an elevated risk of lung cancer. They must be able to undergo CT scans, have not had chest CTs in the past two years, no recent chemotherapy, and cannot have been previously diagnosed with lung cancer.Check my eligibility
What is being tested?
The ILST is testing whether low-dose CT scans can effectively screen for early lung cancer in individuals at high risk due to their age and smoking history. The goal is to see if this screening method can reduce deaths from lung cancer by catching it earlier.See study design
What are the potential side effects?
While the trial itself involves low-risk procedures, potential side effects mainly relate to exposure to radiation from the CT scan which may slightly increase the risk of developing cancer over one's lifetime.
ILST Trial Eligibility Criteria
Inclusion Criteria
You may be eligible if you check “Yes” for the criteria belowSelect...
I am currently smoking or have quit smoking for at least a year.
Select...
I am fully active or can carry out light work.
Select...
My lung cancer risk is high, either by a model or because I've smoked a lot.
ILST Trial Timeline
Screening ~ 3 weeks3 visits
Treatment ~ Varies
Follow Up ~ 5 years
Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~5 years
Treatment Details
Study Objectives
Outcome measures can provide a clearer picture of what you can expect from a treatment.Primary outcome measures
Change in quality of life
Number of nodules
The number of Lung cancers
Secondary outcome measures
Cancer detection rate
Types and number of investigations
ILST Trial Design
1Treatment groups
Experimental Treatment
Group I: SingleExperimental Treatment1 Intervention
Single arm only, CT screening of lung
Treatment
First Studied
Drug Approval Stage
How many patients have taken this drug
Low dose CT
2015
N/A
~4310
Find a Location
Who is running the clinical trial?
The University of QueenslandLead Sponsor
140 Previous Clinical Trials
64,216 Total Patients Enrolled
Kwun M FongPrincipal InvestigatorUQTRC at TPCH
Steven LamPrincipal InvestigatorBritish Columbia Cancer Agency
Media Library
Eligibility Criteria:
This trial includes the following eligibility criteria:- I have symptoms like coughing up blood, chest pain, or losing weight unexpectedly.I have cancer outside the lung that was not treated to cure.I have had pneumonia or bronchitis treated with antibiotics in the last 3 months.I am too large to fit into a standard CT scanner.I am between 55 and 80 years old.I cannot lie on my back with my arms over my head for scans.I have not taken chemotherapy or cytotoxic drugs in the last 6 months.I have been diagnosed with lung cancer before.I am currently smoking or have quit smoking for at least a year.I do not want to undergo a spiral chest CT scan.I am fully active or can carry out light work.My lung cancer risk is high, either by a model or because I've smoked a lot.
Research Study Groups:
This trial has the following groups:- Group 1: Single
Awards:
This trial has 1 awards, including:- No Placebo-Only Group - All patients enrolled in this study will receive some form of active treatment.
Timeline:
This trial has the following timeline:- Screening: It may take up to 3 Weeks to process to see if you qualify in this trial.
- Treatment: The duration you will receive the treatment varies.
- Follow Ups: You may be asked to continue sharing information regarding the trial for 6 Months after you stop receiving the treatment.
Frequently Asked Questions
These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.
Is this research study open to participants of all ages, including those under 30?
"This medical trial is only open to individuals aged 55-80. Conversely, there are 378 clinical trials available for those under 18 and 3991 research opportunities for seniors over the age of 65."
Answered by AI
Are there any remaining vacancies for participants in this clinical experiment?
"Information hosted on clinicaltrials.gov elucidates that the recruitment phase for this medical trial has already concluded; it was first posted in April 2017 and last updated in November 2022. Despite this, there are still 4205 other trials actively looking for participants at present."
Answered by AI
Who is eligible for enrollment in this medical experiment?
"This medical study is negotiating with 2000 people suffering from respiratory disorders, ranging in age from 55 to 80. The applicants must satisfy the following prerequisites: male or female gender, former smokers who have abstained for at least 1 year, a 6-year lung cancer risk of ≥1.51% (as determined by PLCOm2012) or >30 pack years of smoking experience and an Eastern Cooperative Oncology Group performance rating between 0 to 1."
Answered by AI
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