ALL Clinical Trials
Here are the 6 most popular medical studies for all
BCL-2 Inhibitor
Low-Intensity Chemotherapy + Venetoclax for Acute Lymphoblastic Leukemia
This trial is testing the side effects and best dose of Venetoclax in combination with low-intensity chemotherapy in patients with B- or T-cell acute lymphoblastic leukemia.
CAR T-cell Therapy
CAR-T Cell Therapy for B-Cell Non-Hodgkin Lymphoma
This trial will study the side effects of huJCAR014 in patients with relapsed or refractory B-cell non-Hodgkin lymphoma or acute lymphoblastic leukemia that have failed other treatments. huJCAR014 CAR-T cells are made in the laboratory by genetically modifying a patient's T cells and may specifically kill cancer cells that have a molecule CD19 on their surfaces. The trial will be conducted in two stages with the first stage focused on finding the right dose and the second stage focused on safety and efficacy.
Popular filter options for all trials
T-Cell Lymphoblastic Leukemia Clinical Trials
View 87 T-Cell Lymphoblastic Leukemia medical studies.
Corticosteroid
Combination Therapy for Acute Lymphoblastic Leukemia in Children and Adolescents
This trial is studying a new way to treat acute lymphoblastic leukemia (ALL). The new way involves using a new, updated set of risk factors to decide how strong the treatment will be and testing a new way of dosing a chemotherapy drug.
JAK Inhibitor
Ruxolitinib + Chemotherapy for Acute Lymphoblastic Leukemia
This trial is testing a new cancer drug, ruxolitinib, in combination with standard chemotherapy to treat B-cell acute lymphoblastic leukemia. The study will first find the best dose of ruxolitinib to use with chemotherapy, then test how well the combination works at that dose.
Monoclonal Antibodies
Blinatumomab + Combination Chemotherapy or Dasatinib + Prednisone + Blinatumomab for Acute Lymphoblastic Leukemia in Older Patients
This trial is studying the side effects and efficacy of blinatumomab and combination chemotherapy or dasatinib and prednisone in treating older patients with acute lymphoblastic leukemia.
ALL Clinical Trials
View 85 ALL medical studies.
Corticosteroid
Combination Therapy for Acute Lymphoblastic Leukemia in Children and Adolescents
This trial is studying a new way to treat acute lymphoblastic leukemia (ALL). The new way involves using a new, updated set of risk factors to decide how strong the treatment will be and testing a new way of dosing a chemotherapy drug.
Monoclonal Antibodies
Blinatumomab + Combination Chemotherapy or Dasatinib + Prednisone + Blinatumomab for Acute Lymphoblastic Leukemia in Older Patients
This trial is studying the side effects and efficacy of blinatumomab and combination chemotherapy or dasatinib and prednisone in treating older patients with acute lymphoblastic leukemia.
CAR T-cell Therapy
CD19 CAR T cells + EGFRt for Acute Lymphoblastic Leukemia
This trial is testing a new cancer treatment involving genetically modified cells from the patient's own body. The goal is to find the maximum tolerated dose and to determine efficacy.
Metastatic Acute Lymphoblastic Leukemia Clinical Trials
View 96 metastatic acute lymphoblastic leukemia medical studies.
CAR T-cell Therapy
CD19 CAR T cells + EGFRt for Acute Lymphoblastic Leukemia
This trial is testing a new cancer treatment involving genetically modified cells from the patient's own body. The goal is to find the maximum tolerated dose and to determine efficacy.
Bcl-2 Inhibitor
Venetoclax + Dasatinib + Prednisone + Rituximab for Philadelphia Chromosome Positive Acute Lymphoblastic Leukemia
This trial is testing the effects of a combination of drugs on patients with a specific type of leukemia. The drugs may work by stopping the growth of cancer cells or by interfering with the ability of cancer cells to grow and spread.
CD19 Positive Clinical Trials
View 12 CD19 positive medical studies.
CAR T-cell Therapy
CD19 CAR T cells + EGFRt for Acute Lymphoblastic Leukemia
This trial is testing a new cancer treatment involving genetically modified cells from the patient's own body. The goal is to find the maximum tolerated dose and to determine efficacy.
Anti-tumor antibiotic
Chemotherapy + Tafasitamab for Acute Lymphoblastic Leukemia
This trial tests a new chemotherapy regimen with the addition of targeted therapy for the treatment of patients with newly diagnosed Philadelphia chromosome negative B acute lymphoblastic leukemia.
BCR-ABL1 Positive Clinical Trials
View 9 BCR-ABL1 positive medical studies.
Anti-tumor antibiotic
Combination Chemotherapy for Acute Lymphoblastic Leukemia
This trial will study combination chemotherapy in young patients with newly diagnosed B acute lymphoblastic leukemia that is likely to come back or spread, and in patients with Philadelphia chromosome (Ph)-like tyrosine kinase inhibitor (TKI) sensitive mutations.
Corticosteroid
Venetoclax + Ponatinib + Dexamethasone for Leukemia
This trial is testing the combination of venetoclax, ponatinib, and dexamethasone to treat participants with relapsed or refractory acute lymphoblastic leukemia or chronic myelogenous leukemia.
Phase 3 Acute Lymphoblastic Leukemia Clinical Trials
View 96 phase 3 acute lymphoblastic leukemia medical studies.
Corticosteroid
Combination Therapy for Acute Lymphoblastic Leukemia in Children and Adolescents
This trial is studying a new way to treat acute lymphoblastic leukemia (ALL). The new way involves using a new, updated set of risk factors to decide how strong the treatment will be and testing a new way of dosing a chemotherapy drug.
Tyrosine Kinase Inhibitor
Combination Chemotherapy for Philadelphia Chromosome Positive Acute Lymphoblastic Leukemia
This trial is studying the combination of imatinib mesylate with two different chemotherapy regimens to treat patients with newly diagnosed Philadelphia chromosome positive acute lymphoblastic leukemia.
Chemotherapy
Idarubicin +19 More for Acute Lymphoblastic Leukemia
This trial is using novel precision medicine strategies based on inherited and acquired leukemia-specific genomic features and targeted treatment approaches to improve the cure rate and quality of life of children with acute lymphoblastic leukemia (ALL) and acute lymphoblastic lymphoma (LLy).
Corticosteroid
Combination Chemotherapy + Supportive Care for Acute Lymphoblastic Leukemia or Lymphoblastic Lymphoma
This trial is testing different combinations of chemotherapy drugs to treat patients with newly diagnosed standard-risk acute lymphoblastic leukemia or B-lineage lymphoblastic lymphoma.
Acute Lymphoblastic Leukemia Clinical Trials With No Placebo
View 96 acute lymphoblastic leukemia medical studies that do not have a placebo group.
Corticosteroid
Combination Therapy for Acute Lymphoblastic Leukemia in Children and Adolescents
This trial is studying a new way to treat acute lymphoblastic leukemia (ALL). The new way involves using a new, updated set of risk factors to decide how strong the treatment will be and testing a new way of dosing a chemotherapy drug.
JAK Inhibitor
Ruxolitinib + Chemotherapy for Acute Lymphoblastic Leukemia
This trial is testing a new cancer drug, ruxolitinib, in combination with standard chemotherapy to treat B-cell acute lymphoblastic leukemia. The study will first find the best dose of ruxolitinib to use with chemotherapy, then test how well the combination works at that dose.
Monoclonal Antibodies
Blinatumomab + Combination Chemotherapy or Dasatinib + Prednisone + Blinatumomab for Acute Lymphoblastic Leukemia in Older Patients
This trial is studying the side effects and efficacy of blinatumomab and combination chemotherapy or dasatinib and prednisone in treating older patients with acute lymphoblastic leukemia.
View More All Trials
See another 66 many medical studies focused on all.
Frequently Asked Questions
Introduction to all
What are the top hospitals conducting all research?
In the world of medical research, hospitals play a crucial role in conducting clinical trials to find new treatments and cures for various conditions. When it comes to all types of clinical trials, some esteemed institutions stand out from the rest. One such hospital is the M D Anderson Cancer Center in Houston, which leads the way with an impressive 16 active trials encompassing different diseases and conditions. Interestingly, this renowned center has yet to conduct any previous all-time trials, highlighting their commitment to cutting-edge research that constantly seeks innovative solutions.
Meanwhile, on the west coast in Los Angeles, Children's Hospital Los Angeles is making significant strides with 15 ongoing all-type clinical trials. Similarly driven by a passion for advancing medicine and pediatric care, they have yet to complete any prior all-time trials but are actively contributing towards novel breakthroughs.
In Orange County lies another dedicated institution: Children's Hospital of Orange County. With 14 active all-type clinical trials underway there as well — covering diverse areas of healthcare — researchers at this facility are fervently working towards improving health outcomes for children and adolescents.
Further north along California's Silicon Valley sits Lucile Packard Children's Hospital at Stanford University in Palo Alto. Here too researchers are vigorously engaged in advancing medical knowledge through conducting 13 ongoing all-type clinical studies. While no previous record exists for completed overall trials at this prestigious teaching hospital affiliated with Stanford University School of Medicine; it continues its relentless pursuit of better understanding numerous ailments afflicting young patients today.
Similarly committed to enhancing pediatric healthcare is Washingtong Californson Cancer Center in Houston, which leads the way with an impressive 16 active trials encompassing different diseases and conditions. Interestingly, this renowned center has yet to conduct any previous all-time trials, highlighting their commitment to cutting-edge research that constantly seeks innovative solutions.
Meanwhile, on the west coast in Los Angeles, Children's Hospital Los Angeles is making significant strides with 15 ongoing all-type clinical trials. Similarly driven by a passion for advancing medicine and pediatric care, they have yet to complete any prior all-time trials but are actively contributing towards novel breakthroughs.
In Orange County lies another dedicated institution: Children's Hospital of Orange County. With 14 active all-type clinical trials underway there as well — covering diverse areas of healthcare — researchers at this facility are fervently working towards improving health outcomes for children and adolescents.
Further north along California's Silicon Valley sits Lucile Packard Children's Hospital at Stanford University in Palo Alto. Here too researchers are vigorously engaged in advancing medical knowledge through conducting 13 ongoing all-type clinical studies. While no previous record exists for completed overall trials at this prestigious teaching hospital affiliated with Stanford University School of Medicine; it continues its relentless pursuit of better understanding numerous ailments afflicting young patients today.
Similarly committed to enhancing pediatric healthcare is Washington D.C.'s Children's National Medical Center where they currently have 13 active all-type clinical studies taking place within their walls – exemplifying unwavering dedication towards advancing child-specific treatment options despite having no previously recorded overall trial history themselves.
These leading hospitals represent beacons of hope amidst countless challenges faced within modern medicine’s vast landscape.They demonstrate how collaboration between talented medical professionals coupled with state-of-the-art facilities can accelerate scientific progress to ultimately ensure better health outcomes for patients of all ages. The ongoing clinical trials at these esteemed institutions offer not only a glimpse into the future but also tangible evidence that groundbreaking discoveries are just around the corner.
Which are the best cities for all clinical trials?
Three cities emerge as leading hubs for a diverse range of clinical trials. Chicago, Illinois tops the list with 52 active trials investigating treatments like Blinatumomab, Pharmacological Study, and Cyclophosphamide. Las Vegas, Nevada closely follows with 51 ongoing studies focusing on AKR1C3-activated Prodrug OBI-3424, Pharmacological Study, and Arm A (imatinib mesylate, EsPhALL chemotherapy). New York, Illinois tops the list with 52 active trials investigating treatments like Blinatumomab, Pharmacological Study, and Cyclophosphamide. Las Vegas, Nevada closely follows with 51 ongoing studies focusing on AKR1C3-activated Prodrug OBI-3424, Pharmacological Study, and Arm A (imatinib mesylate, EsPhALL chemotherapy). New York City boasts 44 active trials exploring treatments such as Arm A (imatinib mesylate, EsPhALL chemotherapy), Pharmacological Study, and brexucabtagene autoleucel. These cities serve as thriving centers for cutting-edge research that holds promise for advancing medical knowledge and improving patient outcomes.
Which are the top treatments for all being explored in clinical trials?
In the realm of clinical trials, several top treatments are currently being explored to treat breast cancer. These include:
- Daratumumab: 6 active trials, 134 all-time breast cancer trials (first listed in 2012)
- Belantamab mafodotin: 4 active trials, 26 all-time breast cancer trials (first listed in 2018)
- Lenalidomidet cancer trials (first listed in 2012)
- Belantamab mafodotin: 4 active trials, 26 all-time breast cancer trials (first listed in 2018)
- Lenalidomide: 3 active trials for breast cancer, and a remarkable total of 280 all-time clinical trials (first listed in 2003)
The continuous research and development of these treatments provide hope for advancements in combating this devastating disease.
What are the most recent clinical trials for all?
In the realm of clinical trials for acute lymphoblastic leukemia (ALL), several recent studies offer hope and potential advancements in treatment options. One such trial investigates the efficacy of blinatumomab, a promising therapy being tested in Phase 2 trials. Additionally, fludarabine, cyclophosphamide, and alemtuzumab have shown promise as a combined regimen for ALL patients in both Phase 1 and Phase 2 trials. Another study focuses on the use of hyper-CVAD plus calaspargase pegol treatment to combat this aggressive form of cancer (ALL), several recent studies offer hope and potential advancements in treatment options. One such trial investigates the efficacy of blinatumomab, a promising therapy being tested in Phase 2 trials. Additionally, fludarabine, cyclophosphamide, and alemtuzumab have shown promise as a combined regimen for ALL patients in both Phase 1 and Phase 2 trials. Another study focuses on the use of hyper-CVAD plus calaspargase pegol treatment to combat this aggressive form of cancer. Furthermore, CD19-CAR T cell therapy is under investigation as a potential breakthrough approach to target ALL cells specifically. Lastly, rituximab has demonstrated positive outcomes in Phase 2 trials for individuals with ALL. These ongoing investigations bring renewed optimism to patients battling this challenging disease by exploring innovative solutions that may lead to improved care and better outcomes.
What all clinical trials were recently completed?
Several recent clinical trials have successfully concluded, bringing significant advancements in medical research. Notably, the Washington University School of Medicine completed a trial investigating Uproleselan for multiple myelomae Washington University School of Medicine completed a trial investigating Uproleselan for multiple myeloma treatment in October 2021. Additionally, the National Cancer Institute concluded their study on mRNA-1273 in September 2021. Finally, AgenTus Therapeutics wrapped up their agenT-797 trial in January 2021. These trials showcase the ongoing dedication of researchers and offer hope for improved treatments across various medical fields.