120 Participants Needed

Mobile App Support for Post-Traumatic Stress Disorder

(PTSDCoach911 Trial)

MM
RL
Overseen ByRoberto Lucchini, MD
Age: Any Age
Sex: Any
Trial Phase: Academic
Sponsor: Florida International University
No Placebo GroupAll trial participants will receive the active study treatment (no placebo)

Trial Summary

Do I have to stop taking my current medications for this trial?

The trial protocol does not specify whether you need to stop taking your current medications. However, if you are currently receiving mental health treatment for PTSD, you may not be eligible to participate.

What data supports the effectiveness of the treatment Clinician Supported PTSD Coach, Self Managed PTSD Coach for Post-Traumatic Stress Disorder?

Research shows that the PTSD Coach app, used for self-managing PTSD symptoms, is well-received by users and perceived as helpful. While studies indicate high user satisfaction and potential benefits in managing PTSD symptoms, more research is needed to confirm its effectiveness, especially in diverse populations and settings.12345

Is the PTSD Coach app safe for use in humans?

The PTSD Coach app has been used by many people worldwide and has received high user satisfaction and positive feedback, suggesting it is generally safe for use. However, more research is needed to confirm its safety and effectiveness in different populations.12346

How is the Clinician Supported PTSD Coach treatment different from other PTSD treatments?

The Clinician Supported PTSD Coach treatment is unique because it uses a mobile app to provide psycho-education and self-management tools for PTSD, making it accessible to those who may not have access to traditional therapy due to barriers like stigma or lack of providers. This app-based approach allows for self-management of symptoms and has been adapted for use in multiple countries, offering a flexible and widely accessible option for individuals with PTSD.12347

What is the purpose of this trial?

This study focuses on the mental health challenges faced by the World Trade Center's (WTC) General Responders due to the severe psychological trauma from the WTC collapse. PTSD and depression are among the top mental health conditions affecting these responders. Many members of the WTC Health Program (WTCHP) have relocated to Florida, making up nearly six percent of the cohort. Furthermore, many identify as Latinx, highlighting the need for services in their preferred language to promote health equity. Studies have shown that remotely-delivered, clinician-supported applications (apps) can reduce adverse MH symptoms.PTSD Coach was developed by the Veteran's Administration as a self-managed mobile app and is available at no cost for Android and Apple devices. The primary focus of PTSD Coach is on managing PTSD symptoms. The app offers coping tools such as relaxation exercises and calming self-talk and effective sleep hygiene practices when needed. A recent review evaluated the self-managed PTSD Coach app and found it to be feasible, acceptable, and effective in reducing PTSD symptoms.Clinician-Supported PTSD Coach was developed as a brief intervention for Veterans who were unlikely to use a mobile app on their own. Clinician Supported PTSD Coach combines PTSD Coach mobile app with four remotely-delivered 20-30 minute sessions over 8 weeks with a clinician. Studies with Veterans have reported significant reductions in PTSD and depression symptoms, treatment satisfaction and more treatment sessions attended, when compared with typical mental health care. While promising, none of these studies included WTC General Responders or focused on Latinx populations.Given the promise of these interventions, and the need to provide support for geographically dispersed General Responders in Florida, this study aims to evaluate the feasibility, acceptability, and effectiveness of Clinician Supported PTSD Coach in reducing symptoms of PTSD, depression, anxiety, and sleep disturbances among English and Spanish-speaking WTC General Responders. Participants will be randomly assigned to one of three conditions:1. Clinician-Supported PTSD Coach2. Self-Managed PTSD Coach3. Waitlist Control (no treatment until after follow-up)Assessments will be conducted at the end of treatment (8 weeks) and at follow-up (12 weeks). The study will measure reductions in PTSD, depression, anxiety, and sleep disturbances at 8 weeks and 12 weeks. It is expected that both Clinician Supported PTSD Coach and Self-Managed PTSD Coach will reduce symptoms, with Clinician Supported PTSD Coach showing larger reductions. In addition, to assess feasibility and acceptability, the study will assess engagement, satisfaction, and barriers in both PTSD Coach app conditions.This project aims to fill a significant gap in evidence-based mental health treatments for WTC General Responders. It responds to the WTCHP Scientific Technical Advisory Committee's call for more research on mental health interventions and addresses the critical shortage of rigorously tested app-based remote interventions for dispersed General Responders with PTSD. The study also focuses on Spanish-speaking Latinx General Responders, a group that has not been specifically targeted in previous interventions. The study's findings could lead to the development of readily deployable interventions nationally to meet the mental health needs of WTC responders and survivors, providing a valuable resource for treatment researchers and health care providers.

Research Team

MM

Mark Macgowan, PhD

Principal Investigator

Florida International University

Eligibility Criteria

This trial is for World Trade Center General Responders now living in Florida, who have smartphones and are fluent in English or Spanish. It's not for those with recent suicidal thoughts, low distress levels, severe alcohol use, recent illicit drug use (except cannabis), or significant cognitive impairment.

Inclusion Criteria

World Trade Center General Responders (GRs) currently living in Florida
My age does not limit my participation.
Must have a smartphone device capable of using the PTSD Coach app

Exclusion Criteria

Active or recent (past month) suicidal ideation or attempt
Low levels of distress as measured by the PCL-5 (score below 30)
I am receiving treatment for PTSD.
See 3 more

Timeline

Screening

Participants are screened for eligibility to participate in the trial

2-4 weeks

Treatment

Participants receive either Clinician-Supported PTSD Coach or Self-Managed PTSD Coach over 8 weeks

8 weeks
4 remotely-delivered sessions for Clinician-Supported group

Follow-up

Participants are monitored for changes in PTSD, depression, anxiety, and sleep disturbances

4 weeks

Treatment Details

Interventions

  • Clinician Supported PTSD Coach
  • Self Managed PTSD Coach
Trial Overview The study tests a mobile app called PTSD Coach to manage PTSD symptoms. Participants will either use the app on their own (Self-Managed) or with clinician support over eight weeks. A third group waits without treatment initially. The effectiveness of reducing mental health symptoms is measured after 8 and 12 weeks.
Participant Groups
3Treatment groups
Experimental Treatment
Active Control
Group I: Clinician Supported PTSD CoachExperimental Treatment1 Intervention
PTSD Coach application combined with remotely delivered clinician support, focusing on app use, symptom monitoring, and management strategies.
Group II: Self Managed PTSD Coach applicationActive Control1 Intervention
Participant remotely receives basic instructions on using the PTSD Coach application but receives no further clinician support
Group III: Wait list controlActive Control1 Intervention
No intervention until after the follow-up assessment when they have a choice of receiving either CS PTSD Coach or SM PTSD Coach.

Find a Clinic Near You

Who Is Running the Clinical Trial?

Florida International University

Lead Sponsor

Trials
114
Recruited
19,400+

National Institute for Occupational Safety and Health (NIOSH/CDC)

Collaborator

Trials
44
Recruited
50,000+

Centers for Disease Control and Prevention

Collaborator

Trials
902
Recruited
25,020,000+

Findings from Research

The 'PTSD Coach' intervention, available as both a web-based and mobile application, is feasible and generally well-accepted among trauma-exposed individuals, with high satisfaction reported in most studies.
However, the effectiveness of the 'PTSD Coach' in significantly reducing posttraumatic stress symptoms (PTSS) remains unclear, as the pooled effect size was not statistically significant, indicating a need for further research, especially in low-middle-income countries.
Feasibility, acceptability, and effectiveness of web-based and mobile PTSD Coach: a systematic review and meta-analysis.Bröcker, E., Suliman, S., Olff, M., et al.[2023]
The pilot study involving 49 trauma survivors indicated that the PTSD Coach app is feasible and acceptable, with participants using it frequently and reporting it as moderately helpful for managing their symptoms.
While the app showed modest effect sizes for PTSD symptom improvement, the results were not statistically significant, suggesting that more research is needed to fully evaluate its efficacy.
Feasibility, acceptability, and potential efficacy of the PTSD Coach app: A pilot randomized controlled trial with community trauma survivors.Miner, A., Kuhn, E., Hoffman, JE., et al.[2022]
A smartphone-based intervention program for military service members with subthreshold PTSD symptoms showed significant reductions in PTSD Checklist scores from baseline to post-intervention, with effects maintained at a 3-month follow-up.
The program, which included a Skype session and daily text messages guiding app use, was found to be feasible and acceptable to participants, indicating potential for broader application in addressing PTSD symptoms in military populations.
GETSmart: Guided Education and Training via Smart Phones to Promote Resilience.Roy, MJ., Highland, KB., Costanzo, MA.[2022]

References

Preliminary evaluation of PTSD Coach, a smartphone app for post-traumatic stress symptoms. [2022]
PTSD Coach around the world. [2022]
Feasibility, acceptability, and effectiveness of web-based and mobile PTSD Coach: a systematic review and meta-analysis. [2023]
Feasibility, acceptability, and potential efficacy of the PTSD Coach app: A pilot randomized controlled trial with community trauma survivors. [2022]
Using PTSD Coach in primary care with and without clinician support: a pilot randomized controlled trial. [2022]
GETSmart: Guided Education and Training via Smart Phones to Promote Resilience. [2022]
Clinicians' perceptions of PTSD Coach Australia. [2022]
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