Auditory Stimulation for Schizophrenia

N/A

Recruiting

Led By Dara Manoach, PhD

Research Sponsored by Massachusetts General Hospital

Eligibility Criteria Checklist

Specific guidelines that determine who can or cannot participate in a clinical trial

Must have

Male and female schizophrenia outpatients

Be between 18 and 65 years old

Must not have

Be younger than 18 years old

Be older than 65 years old

Timeline

Screening 3 weeks

Treatment Varies

Follow Upplacebo and auditory stimulation naps will be approximately one week apart

Awards & highlights

Study Summary

This trial will test whether playing quiet sounds during sleep can normalize brain activity and improve memory in patients with schizophrenia.

Eligibility Criteria

Inclusion Criteria

You will be eligible if you check “Yes” for the criteria below

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The study is looking for male and female outpatients who have schizophrenia.

Timeline

Screening ~ 3 weeks3 visits

Treatment ~ Varies

Follow Up ~ placebo and auditory stimulation naps will be approximately one week apart

Screening ~ 3 weeks

Treatment ~ Varies

Follow Up ~placebo and auditory stimulation naps will be approximately one week apart

This trial's timeline: 3 weeks for screening, Varies for treatment, and placebo and auditory stimulation naps will be approximately one week apart for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.

Primary outcome measures

Differences in slow-oscillation spindle coupling

Secondary outcome measures

Differences in sleep spindles

Differences in sleep-dependent consolidation of motor procedural memory

Differences in slow oscillations

Trial Design

2Treatment groups

Experimental Treatment

Group I: SchizophreniaExperimental Treatment2 Interventions

Adult outpatients with a diagnosis of schizophrenia.

Group II: Healthy ControlsExperimental Treatment2 Interventions

Adult participants screened to exclude a personal history of mental illness, family history of schizophrenia spectrum disorder, and psychoactive medication use.

0 / 1Eligibility criteria met

Find a site

Who is running the clinical trial?

Massachusetts General HospitalLead Sponsor

2,832 Previous Clinical Trials

13,567,211 Total Patients Enrolled

44 Trials studying Schizophrenia

9,134 Patients Enrolled for Schizophrenia

Dara Manoach, PhDPrincipal Investigator

Massachusetts General Hospital

2 Previous Clinical Trials

80 Total Patients Enrolled

Media Library

Auditory Stimulation Clinical Trial Eligibility Overview. Trial Name: NCT04783571 — N/A

Schizophrenia Research Study Groups: Schizophrenia, Healthy Controls

Schizophrenia Clinical Trial 2023: Auditory Stimulation Highlights & Side Effects. Trial Name: NCT04783571 — N/A

Auditory Stimulation 2023 Treatment Timeline for Medical Study. Trial Name: NCT04783571 — N/A

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Are any new participants being taken on for this clinical research program?

"As indicated on the clinicaltrials.gov, this medical investigation is actively searching for participants. It was originally posted to the website in April of 2020 and last updated August 2021."

Answered by AI

Does this medical trial accept patients aged fifty and older?

"Patients 18 years of age or older but not yet 50 will be considered for enrollment in this research."

Answered by AI

Does my profile qualify me to partake in this trial?

"This clinical trial seeks to enlist approximately 70 participants with a diagnosis of schizophrenia and an age range between 18-50 years old."

Answered by AI

To what extent is the trial population being monitored?

"Affirmative, the information available on clinicaltrials.gov verifies that this medical trial is presently searching for eligible candidates. It was initially published on April 13th of 2020 and most recently updated on August 16 2021. 70 subjects are needed at a single site to participate in the study."

Answered by AI

Recent research and studies

clinicaltrials.govStudy

Effects of Auditory Stimulation on Sleep and Memory in Schizophrenia

Dara S. Manoach, PhD 2020. "Effects of Auditory Stimulation on Sleep and Memory in Schizophrenia". ClinicalTrials.gov. https://clinicaltrials.gov/ct2/show/NCT04783571.