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MyoCI + Memory Reactivation for Stroke Recovery

N/A
Recruiting
Led By Marc W Slutzky, MD/PhD
Research Sponsored by Northwestern University
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Age at enrollment is 21 or older
Severe to moderate motor impairment (FMA-UE of 7-40)
Timeline
Screening 3 weeks
Treatment Varies
Follow Up change from baseline at 6 weeks
Awards & highlights

Study Summary

This trial will study the effects of a myoelectric computer interface training combined with targeted memory reactivation during sleep in people who have had a stroke.

Who is the study for?
This trial is for chronic stroke survivors aged 21 or older with severe to moderate arm motor impairment, who had their first stroke at least 6 months ago. Participants must have some voluntary shoulder and elbow movement but can't join if they have ferromagnetic implants, are in other studies, struggle with English due to aphasia, suffer from substantial pain or visual impairments that affect screen viewing, or have received spasticity treatment recently.Check my eligibility
What is being tested?
The study tests whether combining myoelectric computer interface (MyoCI) training with targeted memory reactivation (TMR) during sleep can improve arm function in people who've had a stroke. It looks at the effects of this combination over an extended period.See study design
What are the potential side effects?
The description does not specify side effects; however, typical risks may include discomfort from wearing the MyoCI device or fatigue from the exercises. TMR involves audio cues during sleep which should be minimally invasive.

Eligibility Criteria

Inclusion Criteria

You may be eligible if you check “Yes” for the criteria below
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I am 21 years old or older.
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I have severe to moderate difficulty moving my arms.

Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~change from baseline at 6 weeks
This trial's timeline: 3 weeks for screening, Varies for treatment, and change from baseline at 6 weeks for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.
Primary outcome measures
Wolf Motor Function Test (WMFT)
Secondary outcome measures
Fugl-Meyer Assessment of Upper Extremity (UE) Motor Function
Modified Ashworth Scale
Motor Activity Log (MAL)

Trial Design

4Treatment groups
Experimental Treatment
Placebo Group
Group I: Slow-wave sleep (SWS) only TMRExperimental Treatment1 Intervention
TMR during slow-wave sleep only
Group II: Reduced frequency TMRExperimental Treatment1 Intervention
TMR during only subset of sessions
Group III: All phase TMRExperimental Treatment1 Intervention
TMR during every stage of sleep
Group IV: Sham TMRPlacebo Group1 Intervention
Patients receive no TMR

Find a Location

Who is running the clinical trial?

Northwestern UniversityLead Sponsor
1,586 Previous Clinical Trials
916,911 Total Patients Enrolled
30 Trials studying Stroke
25,135 Patients Enrolled for Stroke
Marc W Slutzky, MD/PhDPrincipal InvestigatorNorthwestern University

Media Library

MyoCI Clinical Trial Eligibility Overview. Trial Name: NCT04312269 — N/A
MyoCI 2023 Treatment Timeline for Medical Study. Trial Name: NCT04312269 — N/A
Stroke Clinical Trial 2023: MyoCI Highlights & Side Effects. Trial Name: NCT04312269 — N/A
Stroke Research Study Groups: All phase TMR, Sham TMR, Slow-wave sleep (SWS) only TMR, Reduced frequency TMR

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

What is the scope of enrollees for this research project?

"Affirmative. Per the information published on clinicaltrials.gov, this experiment is presently seeking applicants and was initially advertised on February 25th 2020 before being revised on March 14th 2022. The endeavour requires 70 test subjects to be identified from 1 medical centre."

Answered by AI

Is this research trial still taking on new participants?

"Confirmed. Clinicaltrials.gov data affirms that this investigation, which was first announced on February 25th 2020, is actively searching for individuals to take part in it. 70 volunteers will be recruited from a single medical facility."

Answered by AI

Am I eligible to participate in this experiment?

"To be admitted to the trial, candidates must have had a stroke and lie between 21-100 years old. A total of 70 participants are being sought for this study."

Answered by AI

Are senior citizens above the age of seventy eligible for this scientific experiment?

"This trial is seeking patients between 21 and 100 years of age. In contrast, there are 37 clinical trials for minors and 1006 studies that cater to seniors over 65."

Answered by AI

Who else is applying?

What state do they live in?
Illinois
How old are they?
65+
What site did they apply to?
Northwestern University
What portion of applicants met pre-screening criteria?
Met criteria
Recent research and studies
clinicaltrials.govStudy
Combining MyoCI With Memory Reactivation to Improve Motor Recovery After Stroke
Marc Slutzky 2020. "Combining MyoCI With Memory Reactivation to Improve Motor Recovery After Stroke". ClinicalTrials.gov. https://clinicaltrials.gov/ct2/show/NCT04312269.
All > Memory > Stroke
~9 spots leftby Nov 2024
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