Targeted Memory Reactivation (TMR) for Stroke

Northwestern University, Chicago, IL
StrokeTargeted Memory Reactivation (TMR) - Other
Eligibility
21 - 100
All Sexes

Study Summary

This trial will study the effects of a myoelectric computer interface training combined with targeted memory reactivation during sleep in people who have had a stroke.

Treatment Effectiveness

Study Objectives

1 Primary · 3 Secondary · Reporting Duration: change from baseline at 6 weeks

Week 10
Fugl-Meyer Assessment of Upper Extremity (UE) Motor Function
Modified Ashworth Scale
Motor Activity Log (MAL)
Week 6
Wolf Motor Function Test (WMFT)

Trial Safety

Trial Design

4 Treatment Groups

All phase TMR
1 of 4
Slow-wave sleep (SWS) only TMR
1 of 4
Reduced frequency TMR
1 of 4
Sham TMR
1 of 4

Experimental Treatment

Non-Treatment Group

70 Total Participants · 4 Treatment Groups

Primary Treatment: Targeted Memory Reactivation (TMR) · Has Placebo Group · N/A

All phase TMR
Other
Experimental Group · 1 Intervention: Targeted Memory Reactivation (TMR) · Intervention Types: Other
Slow-wave sleep (SWS) only TMR
Other
Experimental Group · 1 Intervention: Targeted Memory Reactivation (TMR) · Intervention Types: Other
Reduced frequency TMR
Other
Experimental Group · 1 Intervention: Targeted Memory Reactivation (TMR) · Intervention Types: Other
Sham TMR
Other
ShamComparator Group · 1 Intervention: Targeted Memory Reactivation (TMR) · Intervention Types: Other

Trial Logistics

Trial Timeline

Screening: ~3 weeks
Treatment: Varies
Reporting: change from baseline at 6 weeks

Who is running the clinical trial?

Northwestern UniversityLead Sponsor
1,504 Previous Clinical Trials
866,646 Total Patients Enrolled
30 Trials studying Stroke
25,132 Patients Enrolled for Stroke
Marc W Slutzky, MD/PhDPrincipal InvestigatorNorthwestern University

Eligibility Criteria

Age 21 - 100 · All Participants · 1 Total Inclusion Criteria

Mark “Yes” if the following statements are true for you:
You can move your shoulder and elbow muscles voluntarily.

Who else is applying?

What state do they live in?
Illinois100.0%
How old are they?
65+100.0%
What site did they apply to?
Northwestern University100.0%
What portion of applicants met pre-screening criteria?
Met criteria100.0%

Frequently Asked Questions

What is the scope of enrollees for this research project?

"Affirmative. Per the information published on clinicaltrials.gov, this experiment is presently seeking applicants and was initially advertised on February 25th 2020 before being revised on March 14th 2022. The endeavour requires 70 test subjects to be identified from 1 medical centre." - Anonymous Online Contributor

Unverified Answer

Is this research trial still taking on new participants?

"Confirmed. Clinicaltrials.gov data affirms that this investigation, which was first announced on February 25th 2020, is actively searching for individuals to take part in it. 70 volunteers will be recruited from a single medical facility." - Anonymous Online Contributor

Unverified Answer

Am I eligible to participate in this experiment?

"To be admitted to the trial, candidates must have had a stroke and lie between 21-100 years old. A total of 70 participants are being sought for this study." - Anonymous Online Contributor

Unverified Answer

Are senior citizens above the age of seventy eligible for this scientific experiment?

"This trial is seeking patients between 21 and 100 years of age. In contrast, there are 37 clinical trials for minors and 1006 studies that cater to seniors over 65." - Anonymous Online Contributor

Unverified Answer
Please Note: These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.