Study Summary
This trial will test if an HIV-infected donor liver is safe for transplant.
- HIV (Human Immunodeficiency Virus)
Treatment Effectiveness
Effectiveness Progress
Study Objectives
1 Primary · 39 Secondary · Reporting Duration: 4 years post-transplant
Trial Safety
Safety Progress
Trial Design
3 Treatment Groups
HIVD-/R+
1 of 3
HIVD-/R+ (observational)
1 of 3
HIV D+/R+
1 of 3
Active Control
Experimental Treatment
80 Total Participants · 3 Treatment Groups
Primary Treatment: HIVD+/R+ · No Placebo Group · N/A
Trial Logistics
Trial Timeline
Who is running the clinical trial?
Eligibility Criteria
Age 18+ · All Participants · 14 Total Inclusion Criteria
Mark “Yes” if the following statements are true for you:- Werbel, William A, Diane M Brown, Oyinkansola T Kusemiju, Brianna L Doby, Shanti M Seaman, Andrew D Redd, Yolanda Eby, et al.. 2021. “National Landscape of Human Immunodeficiency Virus–positive Deceased Organ Donors in the United States”. Clinical Infectious Diseases. Oxford University Press (OUP). doi:10.1093/cid/ciab743.
- Werbel, William A, Diane M Brown, Oyinkansola T Kusemiju, Brianna L Doby, Shanti M Seaman, Andrew D Redd, Yolanda Eby, et al.. 2021. “National Landscape of Human Immunodeficiency Virus–positive Deceased Organ Donors in the United States”. Clinical Infectious Diseases. Oxford University Press (OUP). doi:10.1093/cid/ciab743.
- 2019. "HOPE in Action Trial of HIV+ Deceased Donor Liver Transplants for HIV+ Recipients". ClinicalTrials.gov. https://clinicaltrials.gov/ct2/show/NCT03734393.
Frequently Asked Questions
How many participants are currently benefitting from this trial?
"This study requires 80 compliant participants, and individuals may enroll from either Weill Cornell Medical College in New York or the University of Cincinnati in Ohio." - Anonymous Online Contributor
Is enrollment for this experiment currently available to participants?
"Clinicaltrials.gov notes that this research trial is presently seeking candidates, with the original post date on April 1st 2019 and the most recent update being recorded May 4th 2022." - Anonymous Online Contributor
How many health care facilities are actively conducting this trial?
"In addition to Weill Cornell Medical College in New York, University of Cincinnati in Ohio, and the University of Miami in Florida, this trial is also recruiting participants at 24 other sites." - Anonymous Online Contributor