cTBS for Consolidation

Phase-Based Estimates
1
Effectiveness
1
Safety
McGill Univeristy, Montréal, Canada
+1 More
cTBS - Other
Eligibility
18 - 65
All Sexes
Eligible conditions
Consolidation

Study Summary

Sensory Memory in Speech Motor Learning

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Eligible Conditions

  • Consolidation
  • Speech

Treatment Effectiveness

Effectiveness Estimate

1 of 3

Study Objectives

This trial is evaluating whether cTBS will improve 2 primary outcomes in patients with Consolidation. Measurement will happen over the course of Performance as measured at the end of learning (single day experiment).

Performance as measured at the end of learning (single day experiment)
Speech Motor Learning
Single day experiment
Sensory Memory

Trial Safety

Safety Estimate

1 of 3

Trial Design

5 Treatment Groups

No Control Group
Auditory Sensory Memory

This trial requires 120 total participants across 5 different treatment groups

This trial involves 5 different treatments. CTBS is the primary treatment being studied. Participants will be divided into 5 treatment groups. There is no placebo group. The treatments being tested are not being studied for commercial purposes.

Auditory Sensory Memory
Behavioral
Auditory Sensory Memory
Adaptation to Altered Auditory Feedback
Behavioral
Adaptation to Altered Auditory Feedback
Somatosensory Sensory Memory
Behavioral
Somatosensory Sensory Memory
Adaptation to Altered Auditory Feedback + cTBS to 46vAdaptation to Altered Auditory Feedback + cTBS to 46v
Sensory Memory + cTBS to 46vSensory Memory + cTBS to 46v

Trial Logistics

Trial Timeline

Approximate Timeline
Screening: ~3 weeks
Treatment: Varies
Reporting: single day experiment
This trial has the following approximate timeline: 3 weeks for initial screening, variable treatment timelines, and roughly single day experiment for reporting.

Closest Location

McGill Univeristy - Montréal, Canada

Eligibility Criteria

This trial is for patients born any sex between 18 and 65 years old. There are 2 eligibility criteria to participate in this trial as listed below.

Mark “yes” if the following statements are true for you:
right handed adults
There are no known physical or neurological abnormalities. show original

Patient Q&A Section

Please Note: These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Has ctbs proven to be more effective than a placebo?

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To the best of this authors knowledge, CTPBs have not demonstrated an improved therapeutic effect as compared to a placebo; however, some studies are still undergoing peer-review.

Unverified Answer

What is speech?

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Speech is the production of and understanding of sounds. The disorder includes impairment of verbal expression, oral reading, the ability to listen to speech and to understand speech. speech disorders may not necessarily be present.\n

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How many people get speech a year in the United States?

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Around 12 million Americans have difficulty in the expression of language a year. These difficulties can be due to a number of factors including age, brain diseases, and other disorders.

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What are the latest developments in ctbs for therapeutic use?

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This article highlights the latest developments in clinical trials of ctbs for therapeutic use. The data also provides clinical evidence for the efficacy and tolerability of ctbs in treating patients with ctbs-related neurological conditions.

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What are common treatments for speech?

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Although speech therapy is not usually a part of treatment, there is a growing trend toward specialized speech therapy. More research is needed into the extent of speech therapy's role in managing speech disorders in other populations with communication disorders.

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Can speech be cured?

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Patients with laryngectomy suffer a significant drop in their quality of life, and their subjective satisfaction with therapy is often low. Speech therapy may have a limited role in facilitating improved self-esteem and quality of life in laryngectomized patients, but further research is needed.

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What are the signs of speech?

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Speech is an important part of a person's experience and is particularly important when they are a child. Many people, however, experience the stigma of having a speech disorder (SDD), such as an stutter, making them feel uneasy, anxious or intimidated. This research will help inform and support others whose children possess a speech disorder to feel as well as possible.

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What causes speech?

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Because the vocal tract is so critical for the sound of the human voice, the study of congenital voice disorders is of great importance. The underlying cause of this dysfunction requires further exploration.

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What is the average age someone gets speech?

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Older people with stuttering are more likely to be male and have higher education and higher-risk lifestyles in a population of people with stuttering. Speech professionals should be aware of their patients' demographics so they can support them in recovery and treatment at any age.

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What is the primary cause of speech?

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There is a primary cause of speech which is the [language of articulation] rather than [language of the language-using organism.] The [language-of-articulation] of speech is the result of [the interaction of factors that affect speech-like (sic) function in the mouth|-like function] rather than [the primary cause of language].

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How does ctbs work?

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Our studies suggest a model in which CTB promotes ER stress, which in turn activates Bax and Bid in MCT cells through the PERK/eIF3 signaling pathway. These data are consistent with the model that CTB promotes apoptosis in neuronal cells through ER stress.

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What are the common side effects of ctbs?

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Common side effects of ctbs are headache, constipation, dizziness, and loss of hearing. Serious side effects were uncommon. Physicians should check side effects twice a day and call for further evaluation when the patient has persistent side effects or when there does not respond to ctbs. It seems the patient with ctbs also have poor quality of life.

Unverified Answer
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