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Functional magnetic resonance imaging (fMRI) for Nicotine Addiction

Phase-Based Progress Estimates
1
Effectiveness
1
Safety
Nicotine AddictionFunctional magnetic resonance imaging (fMRI) - Other
Eligibility
25 - 65
All Sexes
What conditions do you have?
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Study Summary

This trial will test a new method to help smokers quit by reducing cravings.

Eligible Conditions
  • Nicotine Addiction

Treatment Effectiveness

Effectiveness Progress

1 of 3

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1
Functional Magnetic Resonance Imaging (fMRI)
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Magnetic Resonance Imaging
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Flavor

Study Objectives

5 Primary · 0 Secondary · Reporting Duration: Between Week 1 and Week 26

Week 26
Mean Change in Blood Pressure
Mean Change in Heart Rate
Mean Change in Skin Conductance
Mean Change on Craving Questionnaire Score
Mean Change on Mood Form Score

Trial Safety

Safety Progress

1 of 3

Similar Trials

1
Functional Magnetic Resonance Imaging (fMRI)
1
Magnetic Resonance Imaging
1
Flavor

Trial Design

2 Treatment Groups

R-E (Retrieval Extinction) with fMRI
1 of 2
R-E (Retrieval Extinction) with no fMRI
1 of 2

Experimental Treatment

166 Total Participants · 2 Treatment Groups

Primary Treatment: Functional magnetic resonance imaging (fMRI) · No Placebo Group · N/A

R-E (Retrieval Extinction) with fMRIExperimental Group · 2 Interventions: Retrieval Extinction Training (RET), Functional magnetic resonance imaging (fMRI) · Intervention Types: Behavioral, Other
R-E (Retrieval Extinction) with no fMRIExperimental Group · 2 Interventions: Retrieval Extinction Training (RET), No functional magnetic resonance imaging (fMRI) · Intervention Types: Behavioral, Other

Trial Logistics

Trial Timeline

Screening: ~3 weeks
Treatment: Varies
Reporting: between week 1 and week 26

Who is running the clinical trial?

Medical University of South CarolinaLead Sponsor
838 Previous Clinical Trials
5,378,402 Total Patients Enrolled
1 Trials studying Nicotine Addiction
77 Patients Enrolled for Nicotine Addiction
National Institutes of Health (NIH)NIH
2,444 Previous Clinical Trials
24,578,277 Total Patients Enrolled
3 Trials studying Nicotine Addiction
380 Patients Enrolled for Nicotine Addiction
National Institute on Drug Abuse (NIDA)NIH
2,250 Previous Clinical Trials
2,029,186 Total Patients Enrolled
12 Trials studying Nicotine Addiction
2,001 Patients Enrolled for Nicotine Addiction
Michael Saladin, PhDPrincipal InvestigatorMedical University of South Carolina
3 Previous Clinical Trials
242 Total Patients Enrolled
1 Trials studying Nicotine Addiction
77 Patients Enrolled for Nicotine Addiction

Eligibility Criteria

Age 25 - 65 · All Participants · 4 Total Inclusion Criteria

Mark “Yes” if the following statements are true for you:
You must live within a 50-mile radius of the research facility
You are willing to abstain from smoking starting the night before the baseline visit, and starting the night before visit 1 and remain abstinent for four consecutive days.
References

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