Behavioral Memory Modulation for Nicotine Addiction
Trial Summary
What is the purpose of this trial?
The purpose of the study is to see if a behavioral intervention known as retrieval-extinction training (RET) might affect craving in response to nicotine cues (e.g., pictures, videos and objects) and smoking behavior in men and women who smoke cigarettes.
Research Team
Michael Saladin, PhD
Principal Investigator
Medical University of South Carolina
Eligibility Criteria
This trial is for healthy adults aged 25-65 who have smoked at least 10 cigarettes daily for over 3 years. They must live within a 50-mile radius of the research site, have reliable transport, and not use other smoking cessation aids during the study. Participants should be willing to stop smoking before certain visits and stay smoke-free for four days.Inclusion Criteria
Exclusion Criteria
Timeline
Screening
Participants are screened for eligibility to participate in the trial
Baseline Assessment
Participants undergo a lab-based smoking-related or non-smoking cue-reactivity experience
Intervention
Participants undergo 3 sessions of Retrieval Extinction Training (RET) or control intervention on consecutive days
Follow-up
Participants are monitored for safety and effectiveness after treatment with follow-up tests and questionnaires
Treatment Details
Interventions
- Control Retrieval Extinction Training (RET)
- Retrieval Extinction Training (RET)
Find a Clinic Near You
Who Is Running the Clinical Trial?
Medical University of South Carolina
Lead Sponsor
National Institutes of Health (NIH)
Collaborator
National Institute on Drug Abuse (NIDA)
Collaborator