Study Summary
This trial is testing a new, less intense chemotherapy treatment followed by a bone marrow transplant from a donor with a partial match, and then lower doses of immunosuppressive drugs.
- Refractory and/or Relapsed Metastatic Solid Tumors
Treatment Effectiveness
Study Objectives
1 Primary · 10 Secondary · Reporting Duration: up to 2 years
Trial Safety
Trial Design
1 Treatment Group
Reduced intensity conditioning
1 of 1
Experimental Treatment
60 Total Participants · 1 Treatment Group
Primary Treatment: Tacrolimus · No Placebo Group · Phase 2
Trial Logistics
Trial Timeline
Who is running the clinical trial?
Eligibility Criteria
Age 1 - 50 · All Participants · 14 Total Inclusion Criteria
Mark “Yes” if the following statements are true for you:Frequently Asked Questions
Which type of patient would be ideal for this clinical trial?
"To participate in this study, patients must have cancer and be between the ages of 1 year old to 50 years old. Currently, the clinical trial is looking for 60 total patients." - Anonymous Online Contributor
How many people will be given the chance to participate in this clinical trial?
"Yes, according to the most recent update on clinicaltrials.gov, this trial is still looking for patients. The study was first posted almost 9 years ago on March 27th, 2013 and is seeking a total of 60 participants at 5 different locations." - Anonymous Online Contributor
Is the age limit for this experiment set at 70 years or below?
"This particular clinical trial requires that potential participants are aged between 1 year and 50 years old." - Anonymous Online Contributor
What is the standard function of Tacrolimus?
"Tacrolimus is an immunosuppressant medication that can be used to manage dermatitis, atopic conditions, multiple sclerosis, and acute myelocytic leukemia." - Anonymous Online Contributor
Where are patients able to participate in this trial?
"At the moment, investigators are looking for volunteers at 5 different study sites. If you live near Valhalla, Charlotte or Baltimore, it might be easier for you to participate because travel would be minimal." - Anonymous Online Contributor
Are there any more open slots for this research study?
"The listed information on clinicaltrials.gov suggests that this study is looking for more participants. The original posting was on March 27th, 2013 with the most recent edit being on August 12th, 2022." - Anonymous Online Contributor
When did the FDA approve the use of Tacrolimus?
"There is some data indicating that Tacrolimus is safe, but none yet supporting that it effective. Consequently, it received a score of 2." - Anonymous Online Contributor
What other scientific investigations have utilized Tacrolimus?
"At the moment, there are 1065 separate clinical trials researching tacrolimus. Out of those, 190 are in Phase 3. Most of the tacrolimus trials are based out of Philadelphia, Pennsylvania; however, 30089 different locations worldwide are running some form of trial for this medication." - Anonymous Online Contributor