This trial will enroll 45 subjects with metastatic or unresectable soft tissue sarcoma or bone sarcoma. All subjects will receive Abemaciclib 200 mg twice daily until progression or discontinuation criteria are met.
- Soft Tissue Sarcoma
2 Primary · 0 Secondary · Reporting Duration: 12 weeks
Side Effects for
1 Treatment Group
1 of 1
45 Total Participants · 1 Treatment Group
Primary Treatment: Abemaciclib · No Placebo Group · Phase 2
Who is running the clinical trial?
Age 18+ · All Participants · 31 Total Inclusion CriteriaMark “Yes” if the following statements are true for you:
Frequently Asked Questions
Does Abemaciclib have a lot of research backing it?
"The first clinical trial for abemaciclib was in 2009. If you would like more information about the locations of these trials, please call 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) or speak with your personal physician. 97 studies are recruiting patients right now, with many of them based out of Iowa City, Iowa." - Anonymous Online Contributor
Are we still looking for patients to participate in this experiment?
"The clinical trial mentioned is still recruiting patients, with the latest update being on 4/4/2022. The study was initially posted 10/7/2019" - Anonymous Online Contributor
What makes this particular trial unique?
"Abemaciclib's clinical trials started in 2009 with Eli Lilly and Company as the primary sponsor. The first study only involved 220 people but it was enough to get Phase 1 drug approval. Now, there are 97 active studies being conducted in 1275 cities across 41 different countries." - Anonymous Online Contributor
How many people are involved in this research project?
"That is correct. The information available on clinicaltrials.gov says that the trial is currently looking for 45 patients from 4 different sites. The trial was first posted on October 7th, 2019 and most recently updated on April 4th, 2022." - Anonymous Online Contributor
Are there a lot of facilities conducting this research in Canada?
"So far, this clinical trial has recruited patients from the following hospitals: University of Iowa Hospitals and Clinics in Iowa City, Iowa; Washington University in St. Louis in Saint Louis, Missouri; Froedtert Hospital & the Medical College of Wisconsin in Milwaukee, Wisconsin; as well as 4 other locations." - Anonymous Online Contributor
Does Abemaciclib put patients at risk for any adverse health effects?
"Abemaciclib's safety level was estimated to be a 2. This is because, while there is some data supporting safety, there is none that speaks to the efficacy of the medication." - Anonymous Online Contributor
What is the primary indication for Abemaciclib?
"Abemaciclib is most often used as a preventative measure for high-risk patients that are likely to experience cancer recurrence. It can also be used to treat more aggressive forms of breast cancer that are hormone receptor positive and human epidermal growth factor 2 negative." - Anonymous Online Contributor