Popular Trials
CCK-B Receptor Antagonist
Proglumide for Chronic Pancreatitis
This trial tests proglumide, an older drug, to see if it can help people with chronic pancreatitis by blocking a protein that causes inflammation and pain. The study targets patients with severe symptoms and aims to reduce their pain and improve pancreatic function.
Anti-fibrotic agent
Pirfenidone for Acute Pancreatitis
This trial is testing pirfenidone, a medication already used for lung disease, to see if it can help patients with severe acute pancreatitis. The goal is to find out if it is safe and if it can reduce inflammation and improve symptoms. Patients will be monitored closely throughout the study.
Procedure
Endoscopic Surgery Techniques for Pancreatitis
This trial compares two methods of using a camera and tools through the mouth to remove dead tissue from the pancreas in patients with necrotizing pancreatitis. One method does it all at once, while the other does it gradually. The goal is to see which method works better for these patients.
Popular Filters
Trials for Chronic Pancreatitis Patients
Behavioural Intervention
Electrical Acustimulation for Chronic Pancreatitis
This trial will test if a noninvasive acupuncture method called Transcutaneous Electrical Acustimulation (TEA) can help reduce abdominal pain in patients with painful chronic pancreatitis. It involves using a
Behavioral Intervention
Online Pain Management for Chronic Pancreatitis
This trial aims to help people with chronic pancreatitis who suffer from severe abdominal pain. The study will use an online program to teach self-management techniques to reduce pain and improve quality of life. The goal
Behavioural Intervention
Intermittent Fasting for Pancreatitis
This trial is testing intermittent fasting to help people with recurrent acute and chronic pancreatitis. The fasting process releases fatty acids that turn into ketones, providing energy and reducing inflammation and scarring in the pancreas.
Islet Transplantation
Islet Transplant Techniques for Chronic Pancreatitis
This trial is testing whether or not it's better to transplant islets into the omentum (a fold of the peritoneum) or leave them in the liver. They will compare islet function in patients to a group of normal volunteers.
QST for Chronic Pancreatitis
This trial will use a new technique, quantitative sensory testing (QST), to map pain patterns in people with chronic pancreatitis (CP). QST has the potential to improve treatment for CP and may eventually be able to predict response to CP therapies.
Trials for Acute Pancreatitis Patients
Behavioural Intervention
Electrical Acustimulation for Chronic Pancreatitis
This trial will test if a noninvasive acupuncture method called Transcutaneous Electrical Acustimulation (TEA) can help reduce abdominal pain in patients with painful chronic pancreatitis. It involves using a
Behavioral Intervention
Online Pain Management for Chronic Pancreatitis
This trial aims to help people with chronic pancreatitis who suffer from severe abdominal pain. The study will use an online program to teach self-management techniques to reduce pain and improve quality of life. The goal
Diagnostic Test
Diagnostic Imaging for Pancreatitis
This trial seeks to understand how MRI can be used to identify pancreatitis & predict long-term complications. It includes tests like endoscopy, blood tests, stool tests & MRI scans. Some participants will receive intravenous secretin.
Corticosteroid
Corticosteroids for Acute Pancreatitis
This trial is testing if giving hydrocortisone can help patients with severe acute pancreatitis by reducing inflammation. The goal is to see if this treatment can improve their health and reduce the time they need to stay in the hospital. Hydrocortisone seems to be effective in treating the early inflammation associated with severe acute pancreatitis.
Behavioural Intervention
Intermittent Fasting for Pancreatitis
This trial is testing intermittent fasting to help people with recurrent acute and chronic pancreatitis. The fasting process releases fatty acids that turn into ketones, providing energy and reducing inflammation and scarring in the pancreas.
Trials With No Placebo
Behavioural Intervention
Electrical Acustimulation for Chronic Pancreatitis
This trial will test if a noninvasive acupuncture method called Transcutaneous Electrical Acustimulation (TEA) can help reduce abdominal pain in patients with painful chronic pancreatitis. It involves using a
Diagnostic Test
Diagnostic Imaging for Pancreatitis
This trial seeks to understand how MRI can be used to identify pancreatitis & predict long-term complications. It includes tests like endoscopy, blood tests, stool tests & MRI scans. Some participants will receive intravenous secretin.
Behavioural Intervention
Intermittent Fasting for Pancreatitis
This trial is testing intermittent fasting to help people with recurrent acute and chronic pancreatitis. The fasting process releases fatty acids that turn into ketones, providing energy and reducing inflammation and scarring in the pancreas.
QST for Chronic Pancreatitis
This trial will use a new technique, quantitative sensory testing (QST), to map pain patterns in people with chronic pancreatitis (CP). QST has the potential to improve treatment for CP and may eventually be able to predict response to CP therapies.
Serine Protease Inhibitor
Anti-Inflammatory Therapy for Chronic Pancreatitis
This trial will study whether two anti-inflammatory therapies can reduce damage to transplanted islets and improve long-term outcomes for patients with severe chronic pancreatitis who have had their pancreas removed and their islets transplanted into the liver.
View More Related Trials
Frequently Asked Questions
Introduction to pancreatitis
What are the top hospitals conducting pancreatitis research?
Pancreatitis, a condition characterized by inflammation of the pancreas, is an area of intense research and innovation in several top hospitals across the United States. In Pittsburgh, the University of Pittsburgh Medical Center leads the way with four ongoing clinical trials dedicated to pancreatitis. Having started their first recorded trial in 2010, this institution has established itself as a pioneer in understanding and treating this complex condition. Similarly committed to advancing knowledge and treatment options for pancreatitis is the University of Minnesota in Minneapolis, where three active clinical trials are currently underway alongside eight completed studies since their inaugural trial also began in 2010.
Down south at the Medical University of South carolina located within scenic Charleston's vibrant medical landscape; researchers are actively involved in three ongoing pancreatitis trials while also having made significant contributions through twelve previously conducted investigations since initiating their first trial back into 2011.
Further expanding on this list is Cincinnati Children's Hospital Medical Center: they have been conducting pioneering examinations surrounding such cases which can be traced back only seven years ago until year 2014.The Beth Israel Deaconess Medical Center situated amidst Boston’s renowned medical community may seem smaller-scale compared to others but still holds importance with its two current pancreatic clinical tests; furthermore it has contributed towards six earlier held investigations- theirs can be traced all wayback till2004.
These esteemed institutions exemplify dedication and progress when it comes to addressing pancreatitis—an illness that afflicts many individuals worldwide. The collective efforts exhibited by these hospitals offer hope for improved diagnostics, treatments, and ultimately better outcomes for patients battling this challenging condition. Through continued research endeavors such as these groundbreaking trials being carried out across various locations nation-wide - we move closer towards unraveling mysteries associated with pancreatic health & alleviating sufferings experienced by countless individuals globally
Which are the best cities for pancreatitis clinical trials?
Los Angeles, California; Indianapolis, Indiana; Pittsburgh, Pennsylvania; Charleston, South carolina; and Baltimore, Maryland emerge as the top cities for pancreatitis clinical trials. With 8 active trials in Los Angeles exploring treatments such as 0.5 mg/kg (0.3125 mL/kg) and ERCP with miES among others, it showcases promising research opportunities. Indianapolis follows closely behind with 5 ongoing studies focusing on interventions like Dose Escalation Level and Quantitative Sensory Test 1. Additionally, Pittsburgh, Charleston, and Baltimore each have 4 active trials investigating various approaches including ERCP with miES and experimental cohorts. These cities provide patients with pancreatitis access to cutting-edge clinical trials that hold potential for advancing treatment options and improving outcomes.
Which are the top treatments for pancreatitis being explored in clinical trials?
Promising advancements in pancreatitis treatment are emerging from ongoing clinical trials. Ketorolac, a pharmaceutical compound with two active and five all-time trials dedicated to pancreatitis, has been on the scene since 2016. Another contender worth noting is rectal indomethacin, currently being explored in two active and three all-time pancreatitis trials since its introduction in 2014. Additionally, proton pump inhibitors show potential as a treatment option through one active trial and one all-time trial listed starting from 2023. Lastly, hydrocortisone enters the fray with one active trial and one all-time trial dating back to 2022, signaling optimism for improved outcomes among patients battling this challenging condition. These innovative treatments offer hope for enhanced management of pancreatitis symptoms and better patient prognosis.
What are the most recent clinical trials for pancreatitis?
Promising advancements in the field of pancreatitis research offer a glimmer of hope to those affected by this condition. One notable clinical trial involves the use of pirfenidone, which has shown potential as a treatment for pancreatitis. This drug is currently being evaluated in both Phase 1 and Phase 2 trials, with results becoming available on August 1st, 2023. Another study focuses on determining the optimal dosage escalation level for pancreatic therapy through a Phase 1 trial that began on March 17th, 2023. Additionally, researchers are exploring imaging stratification techniques to better understand the stages of pancreatitis in a Phase 4 trial that commenced on January 18th, 2023. Furthermore, rectal indomethacin is under investigation as a possible intervention for pancreatitis patients during a Phase 3 trial initiated on January 18th,2023.Furthermore,a combination therapy involving proglumide is also being studied through dual-phase trials since November17th ,2022.These comprehensive investigations hold great promise for improving treatment outcomes and quality of life among individuals suffering from pancreatitis.
What pancreatitis clinical trials were recently completed?
Recently, two clinical trials focusing on pancreatitis have reached completion, representing significant strides in understanding and treating this condition. In October 2021, AbbVie wrapped up a trial investigating the effectiveness of CREON for managing pancreatitis. Mayo Clinic also conducted a trial examining the potential benefits of Indomethacin in July 2020. These studies contribute valuable insights into the treatment options available for individuals suffering from pancreatitis and bring hope to patients seeking improved outcomes.