Intermittent Fasting for Pancreatitis
(IFPanc Trial)
Trial Summary
Will I have to stop taking my current medications?
The trial does not specify if you need to stop taking your current medications, but it does exclude patients who are on beta blockers.
What data supports the effectiveness of the treatment Intermittent Fasting for Pancreatitis?
Research shows that intermittent fasting, like alternate-day fasting, can help with weight loss and improve heart health in obese adults. Additionally, calorie restriction, a component of intermittent fasting, has been shown to delay the progression of pancreatic cancer in mice, suggesting potential benefits for pancreatic health.12345
Is intermittent fasting safe for humans?
How does intermittent fasting differ from other treatments for pancreatitis?
Intermittent fasting, such as alternate-day fasting, is unique because it involves cycles of eating very little on some days and eating normally on others, which may help manage pancreatitis by reducing inflammation and stress on the pancreas. Unlike traditional treatments that might focus on medication or continuous calorie restriction, this approach uses a specific eating schedule to potentially improve health outcomes.35111213
What is the purpose of this trial?
This trial is testing intermittent fasting to help people with recurrent acute and chronic pancreatitis. The fasting process releases fatty acids that turn into ketones, providing energy and reducing inflammation and scarring in the pancreas.
Eligibility Criteria
This trial is for adults aged 18 to 80 with recurrent acute pancreatitis or chronic pancreatitis, confirmed by specific diagnostic criteria. It's not suitable for pregnant individuals, those unable to consent, patients with certain types of pancreatitis (alcohol or gallstone-induced), pancreatic cancer, diabetes, on beta blockers, under 18 years old, with glycogen storage disease or active alcohol abuse.Inclusion Criteria
Exclusion Criteria
Timeline
Screening
Participants are screened for eligibility to participate in the trial
Treatment
Participants follow either an intermittent fasting regimen or a standard diet approach for 24 weeks
Follow-up
Participants are monitored for safety and effectiveness after treatment
Treatment Details
Interventions
- Intermittent Fasting
- No intermittent fasting
Find a Clinic Near You
Who Is Running the Clinical Trial?
University Hospitals Cleveland Medical Center
Lead Sponsor
H. Lee Moffitt Cancer Center and Research Institute
Lead Sponsor