Cognitive behavioral therapy plus social cognitive training (CBTSCT) for Depression

Phase-Based Progress Estimates
1
Effectiveness
1
Safety
Judy Garber, Nashville, TN
Depression
Cognitive behavioral therapy plus social cognitive training (CBTSCT) - Behavioral
Eligibility
< 18
All Sexes
What conditions do you have?
Select

Study Summary

Depression in youth is a serious public health concern for which more personalized treatments are needed. This randomized controlled trial will test the effect of an intervention aimed at enhancing social cognitive capacities (e.g., ability to take another's perspective), thereby making treatment of depression in youth more efficient and effective. Participants in the R33 (N=82) will be youth between ages 13- through 17-years-old currently experiencing depression. Youth will be randomized to either an enhanced CBT intervention that teaches social cognitive skills, particularly social perspective taking and theory of mind (CBTSCT) as compared to CBT only. The primary target is improvement in both social cognitive skills and depressive symptoms at post-treatment and at a 6-month follow-up.

Treatment Effectiveness

Study Objectives

2 Primary · 0 Secondary · Reporting Duration: after 12 weeks

after 12 weeks
Children's Depression Rating Scale-Revised
Faux Pas Recognition Test

Trial Safety

Trial Design

2 Treatment Groups

Cognitive behavioral therapy (CBT)
1 of 2
Cognitive behavioral therapy plus social cognitive training (CBTSCT)
1 of 2
Active Control
Experimental Treatment

82 Total Participants · 2 Treatment Groups

Primary Treatment: Cognitive behavioral therapy plus social cognitive training (CBTSCT) · No Placebo Group · N/A

Cognitive behavioral therapy plus social cognitive training (CBTSCT)
Behavioral
Experimental Group · 1 Intervention: Cognitive behavioral therapy plus social cognitive training (CBTSCT) · Intervention Types: Behavioral
Cognitive behavioral therapy (CBT)
Behavioral
ActiveComparator Group · 1 Intervention: Cognitive behavioral therapy plus social cognitive training (CBTSCT) · Intervention Types: Behavioral

Trial Logistics

Trial Timeline

Approximate Timeline
Screening: ~3 weeks
Treatment: Varies
Reporting: after 12 weeks
Closest Location: Judy Garber · Nashville, TN
Photo of Nashville 1Photo of Nashville 2Photo of Nashville 3
2021First Recorded Clinical Trial
2 TrialsResearching Depression
1 CompletedClinical Trials

Who is running the clinical trial?

Vanderbilt UniversityLead Sponsor
681 Previous Clinical Trials
6,131,264 Total Patients Enrolled
26 Trials studying Depression
4,966 Patients Enrolled for Depression
National Institute of Mental Health (NIMH)NIH
2,489 Previous Clinical Trials
1,765,828 Total Patients Enrolled
593 Trials studying Depression
241,213 Patients Enrolled for Depression

Eligibility Criteria

Age < 18 · All Participants · 2 Total Inclusion Criteria

Mark “yes” if the following statements are true for you:

About The Reviewer

Michael Gill preview

Michael Gill - B. Sc.

First Published: October 9th, 2021

Last Reviewed: August 12th, 2022

Michael Gill holds a Bachelors of Science in Integrated Science and Mathematics from McMaster University. During his degree he devoted considerable time modeling the pharmacodynamics of promising drug candidates. Since then, he has leveraged this knowledge of the investigational new drug ecosystem to help his father navigate clinical trials for multiple myeloma, an experience which prompted him to co-found Power Life Sciences: a company that helps patients access randomized controlled trials.