Study Summary
This trial is studying a new treatment for Meniere's disease, a chronic condition with symptoms like vertigo, hearing loss, tinnitus, and instability. It's hoped that this new treatment will help improve patients' quality of life.
- Ménière's Disease
Treatment Effectiveness
Effectiveness Progress
Study Objectives
1 Primary · 7 Secondary · Reporting Duration: 8 weeks
Trial Safety
Safety Progress
Trial Design
2 Treatment Groups
hydrochlorothiazide + triamterene + placebo
1 of 2
nortriptyline + topiramate
1 of 2
Active Control
Experimental Treatment
100 Total Participants · 2 Treatment Groups
Primary Treatment: nortriptyline + topiramate · No Placebo Group · Phase 4
Trial Logistics
Trial Timeline
Who is running the clinical trial?
Eligibility Criteria
Age 25 - 85 · All Participants · 4 Total Inclusion Criteria
Mark “Yes” if the following statements are true for you:Frequently Asked Questions
Is there any regulatory endorsement for the combination of nortriptyline and topiramate?
"This combination of drugs is approved, as evidenced by its Phase 4 trial status; thus, it was given a safety score of 3." - Anonymous Online Contributor
For whom is this clinical research appropriate?
"This medical trial is looking to include 100 individuals who suffer from ménière between the ages of 25 and 85. It goes without saying that interested applicants must meet a few requirements, such as being compliant with medications, attending study visits, and having the ability to read and write in English for consent purposes." - Anonymous Online Contributor
Is there capacity for prospective participants in this medical experiment?
"Indeed, the clinical trial is currently accepting participants. The initial posting date was on August 1st 2022 and it has most recently been updated on October 12th of this year." - Anonymous Online Contributor
Does this trial accept applicants of twenty years or older?
"This trial has established an age range of 25 to 85 years old for prospective participants, as stipulated by the eligibility requirements." - Anonymous Online Contributor
To what extent has recruitment been successful for this research study?
"Affirmative. Information available on clinicaltrials.gov implies that this research project is currently seeking participants, having been initially posted on August 1st 2022 and most recently updated on October 12th 2022. The investigators are aiming to enrol 100 individuals from a single site." - Anonymous Online Contributor