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Understanding Episodic Memory in Epilepsy

N/A
Waitlist Available
Led By Ueli Rutishauser, PhD
Research Sponsored by Cedars-Sinai Medical Center
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Ability to comprehend and perform simple behavioral tasks by pressing buttons on laptop computer in response to questions.
Age ≥13
Timeline
Screening 3 weeks
Treatment Varies
Follow Up 5 years
Awards & highlights

Study Summary

This trial is to study how the human brain processes new information, recalls stored information, and makes decisions. This will help researchers understand human cognition and develop treatments for disorders of learning and memory.

Who is the study for?
This trial is for individuals aged 13 or older with intractable epilepsy who are already undergoing invasive monitoring. Participants should have an IQ over 70 and be able to understand and perform tasks on a computer by pressing buttons. Those unable to complete the tasks due to cognitive, psychological limits, or pain cannot join.Check my eligibility
What is being tested?
The study aims to understand how humans learn, recall information, and make decisions using various devices: Cedrus response pad for inputs; Adtech micro-electrodes, Neurolynx system for brain activity recording; Blackrock stimulator possibly for stimulating specific brain areas during tests.See study design
What are the potential side effects?
Since this trial involves non-drug interventions focused on monitoring and testing brain function rather than treatment side effects may include discomfort from wearing the equipment or potential risks associated with invasive monitoring as determined by clinicians.

Eligibility Criteria

Inclusion Criteria

You may be eligible if you check “Yes” for the criteria below
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I can understand and respond to simple tasks on a computer.
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I am 13 years old or older.
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I have severe epilepsy and am undergoing special monitoring.

Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~5 years
This trial's timeline: 3 weeks for screening, Varies for treatment, and 5 years for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.
Primary outcome measures
Decision Making (Firing Rates)
Decision Making (Power)
Decision Making (Timing)
+4 more

Trial Design

1Treatment groups
Experimental Treatment
Group I: Behavioral TestingExperimental Treatment1 Intervention
Behavioral and Neuronal Recordings

Find a Location

Who is running the clinical trial?

California Institute of TechnologyOTHER
13 Previous Clinical Trials
2,969 Total Patients Enrolled
Cedars-Sinai Medical CenterLead Sponsor
497 Previous Clinical Trials
164,281 Total Patients Enrolled
Johns Hopkins UniversityOTHER
2,242 Previous Clinical Trials
14,816,437 Total Patients Enrolled
17 Trials studying Epilepsy
1,202 Patients Enrolled for Epilepsy

Media Library

Cedrus RB-844 response pad; Adtech Behnke-Fried micro-electrodes; Neurolynx electrophysiology system; Blackrock Cerestim stimulator Clinical Trial Eligibility Overview. Trial Name: NCT04500119 — N/A
Epilepsy Research Study Groups: Behavioral Testing
Epilepsy Clinical Trial 2023: Cedrus RB-844 response pad; Adtech Behnke-Fried micro-electrodes; Neurolynx electrophysiology system; Blackrock Cerestim stimulator Highlights & Side Effects. Trial Name: NCT04500119 — N/A
Cedrus RB-844 response pad; Adtech Behnke-Fried micro-electrodes; Neurolynx electrophysiology system; Blackrock Cerestim stimulator 2023 Treatment Timeline for Medical Study. Trial Name: NCT04500119 — N/A

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Is registration currently available for this clinical research endeavor?

"Clinicaltrials.gov indicates that this medical experiment, first posted on August 12th 2020 and last updated July 14th 2022, is not presently recruiting participants. Nevertheless, there are 248 other studies currently searching for enrollees."

Answered by AI
~54 spots leftby Aug 2025