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Non-invasive Brain Stimulation
Brain Stimulation for Alzheimer's Disease (MemStim-lab Trial)
N/A
Waitlist Available
Led By Alvaro Pascual-Leone, Dr.
Research Sponsored by Hebrew SeniorLife
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial Must have
Healthy young participants: age 21-35 without any cognitive impairment (based on MoCA or TICS) and willing and capable to give informed consent for the participation in the study after it has been thoroughly explained
Be older than 18 years old
Timeline
Screening 3 weeks
Treatment Varies
Follow Up 3 lab-visits will occur at least 2 days apart within one month
Awards & highlights
MemStim-lab Trial Summary
This trial will study whether brain stimulation can improve memory.
Who is the study for?
This trial is for young adults (21-35) with no cognitive issues, older adults (55+) without cognitive impairment, and older individuals (55+) diagnosed with mild Alzheimer's or Mild Cognitive Impairment. Participants must be able to consent and perform tasks required by the study. Those with severe cognitive deficits, psychiatric conditions, blindness, or who can't undergo brain stimulation are excluded.Check my eligibility
What is being tested?
The trial is testing transcranial alternating current stimulation (tACS), a non-invasive brain stimulation technique, to see if it improves memory function in people with mild Alzheimer's Disease.See study design
What are the potential side effects?
While not explicitly stated here, tACS may cause side effects like headache, scalp tingling or itching during application, fatigue after treatment sessions and in rare cases seizures.
MemStim-lab Trial Eligibility Criteria
Inclusion Criteria
You may be eligible if you check “Yes” for the criteria belowSelect...
I am between 21-35 years old, mentally fit, and can consent to the study.
MemStim-lab Trial Timeline
Screening ~ 3 weeks3 visits
Treatment ~ Varies
Follow Up ~ 3 lab-visits will occur at least 2 days apart within one month
Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~3 lab-visits will occur at least 2 days apart within one month
Treatment Details
Study Objectives
Outcome measures can provide a clearer picture of what you can expect from a treatment.Primary outcome measures
Behavioral performance measured with Montreal Cognitive Assessment (MoCA)
Spatiotemporal dynamic changes measured with electroencephalography (EEG)
MemStim-lab Trial Design
3Treatment groups
Active Control
Group I: Healthy older participantsActive Control1 Intervention
A group of 20 cognitively intact older participants (age 55+)
Group II: Healthy young participantsActive Control1 Intervention
a group of 20 cognitively intact younger participants (age 21-35)
Group III: Older MCI/mild AD participantsActive Control1 Intervention
A group of 20 cognitively impaired older participants (age 55+)
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Who is running the clinical trial?
Hebrew SeniorLifeLead Sponsor
45 Previous Clinical Trials
270,522 Total Patients Enrolled
Alvaro Pascual-Leone, Dr.3.97 ReviewsPrincipal Investigator - Hinda and Arthur Marcus Institute for Aging Research
Hebrew SeniorLife
2 Previous Clinical Trials
25 Total Patients Enrolled
Frequently Asked Questions
These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.
Are there any open spots available for this clinical experiment?
"According to the clinicaltrials.gov website, this medical experiment is not accepting volunteers at present. The trial was initially announced on June 22nd 2020 and its most recent update occurred on June 21st 2022. Although this study does not require participants presently, there are 552 other trials looking for enrolment now."
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