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Noninvasive Brain Stimulation

Noninvasive Brain Stimulation for Mild Cognitive Impairment

N/A

Waitlist Available

Research Sponsored by University of Texas Southwestern Medical Center

Eligibility Criteria Checklist

Specific guidelines that determine who can or cannot participate in a clinical trial

Must have

Native English speakers

Age 50 and older

Timeline

Screening 3 weeks

Treatment Varies

Follow Up baseline, immediately following last hd-tdcs session, and again at 3-month follow-up

Awards & highlights

Study Summary

This trial will test if a certain kind of brain stimulation can improve memory in people with a history of brain injury.

Who is the study for?

This trial is for individuals aged 50 or older, who are native English speakers with at least a high school education. Participants must have mild cognitive impairment due to past traumatic brain injury (TBI), but not within the last two years. They can't join if they've had major cardiovascular events, epilepsy, severe psychiatric disorders, substance use disorder, metal in the head, or take certain medications.Check my eligibility

What is being tested?

The study tests whether ten sessions of High Definition Transcranial Direct Current Stimulation (HD-tDCS) on a specific brain area improve memory in people with cognitive issues from past TBI. Memory will be checked after treatment and three months later.See study design

What are the potential side effects?

While HD-tDCS is generally considered safe, potential side effects may include slight scalp discomfort during stimulation, itching or tingling sensations under the electrodes, headache or fatigue post-session.

Eligibility Criteria

Inclusion Criteria

You may be eligible if you check “Yes” for the criteria below

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I am a native English speaker.

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I am 50 years old or older.

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I have been diagnosed with mild cognitive impairment.

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I have a history of traumatic brain injury as defined by VA/DOD.

Timeline

Screening ~ 3 weeks3 visits

Treatment ~ Varies

Follow Up ~ baseline, immediately following last hd-tdcs session, and again at 3-month follow-up

Screening ~ 3 weeks

Treatment ~ Varies

Follow Up ~baseline, immediately following last hd-tdcs session, and again at 3-month follow-up

This trial's timeline: 3 weeks for screening, Varies for treatment, and baseline, immediately following last hd-tdcs session, and again at 3-month follow-up for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.

Primary outcome measures

Memory

Trial Design

2Treatment groups

Active Control

Placebo Group

Group I: Active HD-tDCSActive Control1 Intervention

Participants will receive 10 sessions of active stimulation (1 mA anodal HD-tDCS targeting dorsal anterior cingulate region for 20 minutes) across 2 weeks, with episodic memory tasks completed at baseline, immediate follow-up after session 10, and a 3-month follow-up.

Group II: Sham HD-tDCSPlacebo Group1 Intervention

Participants will receive 10 sessions of sham stimulation across 2 weeks, with episodic memory tasks completed at baseline, immediate follow-up after session 10, and a 3-month follow-up.

0 / 4Eligibility criteria met

Find a Location

Who is running the clinical trial?

University of Texas Southwestern Medical CenterLead Sponsor

1,047 Previous Clinical Trials

1,053,775 Total Patients Enrolled

U.S. Army Medical Research and Development CommandFED

285 Previous Clinical Trials

245,135 Total Patients Enrolled

Media Library

High Definition Transcranial Direct Current Stimulation (Noninvasive Brain Stimulation) Clinical Trial Eligibility Overview. Trial Name: NCT04504630 — N/A

Mild Cognitive Impairment Research Study Groups: Active HD-tDCS, Sham HD-tDCS

Mild Cognitive Impairment Clinical Trial 2023: High Definition Transcranial Direct Current Stimulation Highlights & Side Effects. Trial Name: NCT04504630 — N/A

High Definition Transcranial Direct Current Stimulation (Noninvasive Brain Stimulation) 2023 Treatment Timeline for Medical Study. Trial Name: NCT04504630 — N/A

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

What is the upper threshold of participants in this trial?

"Affirmative. Per the details listed on clinicaltrials.gov, this medical research venture is actively seeking participants. The trial was initially posted on December 5th 2020 and the most recent update occured 13 days ago in 2021. 24 individuals must be enrolled from a single site to fulfill its requirements."

Answered by AI

Are there vacancies for enrollees in this clinical trial?

"As per the clinicaltrials.gov entry, recruitment for this medical trial is ongoing and started on December 5th 2020. The page was last modified on December 13th 2021."

Answered by AI

Recent research and studies

clinicaltrials.govStudy

Noninvasive Brain Stimulation on Memory in Individuals With Mild Cognitive Impairment and History of Brain Injury

Christian Lobue 2020. "Noninvasive Brain Stimulation on Memory in Individuals With Mild Cognitive Impairment and History of Brain Injury". ClinicalTrials.gov. https://clinicaltrials.gov/ct2/show/NCT04504630.

All > Concussion > Mild Cognitive Impairment