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Vitamin B3 Supplement

Nicotinamide Riboside for Cognitive Impairment and Sleep Quality

N/A

Recruiting

Research Sponsored by State University of New York at Buffalo

Eligibility Criteria Checklist

Specific guidelines that determine who can or cannot participate in a clinical trial

Must have

Be older than 65 years old

Timeline

Screening 3 weeks

Treatment Varies

Follow Up change from baseline to endpoint at 12 weeks

Awards & highlights

Study Summary

This trial will test whether a form of vitamin B3 can improve sleep and cognitive function in older adults by increasing levels of a protein that supports brain health.

Who is the study for?

This trial is for older adults who have trouble sleeping and may be experiencing some cognitive challenges. To join, they need to score more than 5 on a sleep quality test but can't have dementia as indicated by scoring less than 20 on a mental status questionnaire.Check my eligibility

What is being tested?

The study is testing whether taking Nicotinamide Riboside (NR), a vitamin B3 form, improves sleep and brain function in older adults. Participants will either receive NR or a placebo without active ingredients to compare the effects.See study design

What are the potential side effects?

While not explicitly stated, potential side effects of NR could include nausea, fatigue, headaches, diarrhea, stomach discomfort and indigestion based on its nature as a supplement.

Timeline

Screening ~ 3 weeks3 visits

Treatment ~ Varies

Follow Up ~ change from baseline to endpoint at 12 weeks

Screening ~ 3 weeks

Treatment ~ Varies

Follow Up ~change from baseline to endpoint at 12 weeks

This trial's timeline: 3 weeks for screening, Varies for treatment, and change from baseline to endpoint at 12 weeks for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.

Primary outcome measures

Sleep Quality Assessment

Secondary outcome measures

Cognition

Other outcome measures

Biomarkers

Trial Design

2Treatment groups

Experimental Treatment

Placebo Group

Group I: InterventionExperimental Treatment1 Intervention

Participants in the intervention group will receive 500mg of NR twice daily

Group II: PlaceboPlacebo Group1 Intervention

Participants in the intervention group will receive 500mg of sham placebo twice daily

Treatment

First Studied

Drug Approval Stage

How many patients have taken this drug

Nicotinamide riboside

2021

Completed Phase 3

~400

Do I qualify?Apply below to find out

Find a Location

Who is running the clinical trial?

State University of New York at BuffaloLead Sponsor

246 Previous Clinical Trials

49,458 Total Patients Enrolled

Media Library

Nicotinamide Riboside (Vitamin B3 Supplement) Clinical Trial Eligibility Overview. Trial Name: NCT05500170 — N/A

Cognitive Impairment Research Study Groups: Intervention, Placebo

Cognitive Impairment Clinical Trial 2023: Nicotinamide Riboside Highlights & Side Effects. Trial Name: NCT05500170 — N/A

Nicotinamide Riboside (Vitamin B3 Supplement) 2023 Treatment Timeline for Medical Study. Trial Name: NCT05500170 — N/A

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Is the study open to seniors aged 80 or above?

"As specified in the enrollment criteria, individuals aged between 65 and 85 are qualified to join this research project."

Answered by AI

Is this study currently enrolling new participants?

"According to information on clinicaltrials.gov, this particular medical trial is no longer enrolling participants - it was initially published on December 30th 2022 and underwent its final update on October 12th 2022. Despite that, 634 other studies remain available for potential candidates at the current time."

Answered by AI

Is there an opportunity for me to participate in this clinical research?

"50 senior citizens with poor sleeping quality are required for this trial; the Pittsburgh Sleep Quality Index (PSQI) global score must be greater than 5."

Answered by AI

Recent research and studies

clinicaltrials.govStudy

Benefits of Nicotinamide Riboside Upon Cognition and Sleep

Carleara Weiss 2023. "Benefits of Nicotinamide Riboside Upon Cognition and Sleep". ClinicalTrials.gov. https://clinicaltrials.gov/ct2/show/NCT05500170.