Nitrous Oxide for Obsessive-Compulsive Disorder

Phase-Based Progress Estimates
Obsessive-Compulsive Disorder+1 More
Nitrous Oxide - Drug
All Sexes
What conditions do you have?

Study Summary

This trial looks at whether nitrous oxide, a gas used during surgery to keep people pain-free and relaxed, can help people with OCD who haven't responded to other treatments.

Eligible Conditions
  • Obsessive-Compulsive Disorder

Treatment Effectiveness

Effectiveness Progress

1 of 3

Study Objectives

1 Primary · 0 Secondary · Reporting Duration: 1 week

1 week
Improvement in the severity of OCD symptoms as measured by the Yale-Brown Obsessive Compulsive Scale (YBOCS)

Trial Safety

Safety Progress

2 of 3
This is further along than 68% of similar trials

Trial Design

2 Treatment Groups

Experimental: Nitrous Oxide
1 of 2
Control: Nitrogen
1 of 2

Experimental Treatment

Non-Treatment Group

45 Total Participants · 2 Treatment Groups

Primary Treatment: Nitrous Oxide · Has Placebo Group · Phase 2

Experimental: Nitrous Oxide
Experimental Group · 1 Intervention: Nitrous Oxide · Intervention Types: Drug
Control: Nitrogen
PlaceboComparator Group · 1 Intervention: Nitrogen · Intervention Types: Drug
First Studied
Drug Approval Stage
How many patients have taken this drug
Nitrous oxide
FDA approved

Trial Logistics

Trial Timeline

Screening: ~3 weeks
Treatment: Varies
Reporting: 1 week

Who is running the clinical trial?

Stanford UniversityLead Sponsor
2,148 Previous Clinical Trials
35,678,959 Total Patients Enrolled
10 Trials studying Obsessive-Compulsive Disorder
795 Patients Enrolled for Obsessive-Compulsive Disorder
Brain & Behavior Research FoundationOTHER
54 Previous Clinical Trials
2,547 Total Patients Enrolled
1 Trials studying Obsessive-Compulsive Disorder
148 Patients Enrolled for Obsessive-Compulsive Disorder
Peter J van Roessel, MD, PhD5.02 ReviewsPrincipal Investigator - Stanford Univeristy
Stanford University
1 Previous Clinical Trials
16 Total Patients Enrolled
1 Trials studying Obsessive-Compulsive Disorder
16 Patients Enrolled for Obsessive-Compulsive Disorder

Eligibility Criteria

Age 18+ · All Participants · 5 Total Inclusion Criteria

Mark “Yes” if the following statements are true for you:
You have a primary diagnosis of OCD.
is an important consideration in the treatment of psoriasis
may be compromised in some cases

About The Reviewer

Michael Gill preview

Michael Gill - B. Sc.

First Published: October 29th, 2021

Last Reviewed: November 10th, 2022

Michael Gill holds a Bachelors of Science in Integrated Science and Mathematics from McMaster University. During his degree he devoted considerable time modeling the pharmacodynamics of promising drug candidates. Since then, he has leveraged this knowledge of the investigational new drug ecosystem to help his father navigate clinical trials for multiple myeloma, an experience which prompted him to co-found Power Life Sciences: a company that helps patients access randomized controlled trials.