Dextrose-Enhanced Anesthetic for Chronic Pain
Trial Summary
What is the purpose of this trial?
The goal of this single-arm, non-randomized, open-label trial is to determine whether adding a 5% dextrose solution to a local anesthetic can improve outcomes in patients with chronic non-cancer pain.The main question we aim to answer is whether adding a low-concentration (5%) dextrose solution to local anesthetics increases the effectiveness of trigger point injections and/or peripheral nerve blockade in the treatment of chronic non-cancer pain.Researchers will compare the outcomes of adding 5% dextrose to the usual local anesthetic solution with the outcomes of using the local anesthetic alone to determine if injection therapy is more effective when dextrose is added.Participants will:* Attend their scheduled injection treatments every two (2) weeks for a total of six (6) visits.* Complete a demographic form at the first visit, and the usual pre-visit questionnaires (the Waiting Room Form and the Brief Pain Inventory (BPI)) at every visit, as well as four (4) weeks after the sixth visit (approximately 16 weeks from the study start date). They will also need to complete two short questionnaires-the Patient Health Questionnaire (PHQ-9) and the Patient Global Impression of Change (PGIC)-at the specified intervals.* Complete all forms, which will be securely emailed to them.
Eligibility Criteria
This trial is for individuals with chronic non-cancer pain who regularly receive trigger point injections or peripheral nerve blockade. Participants must be able to attend treatment every two weeks for three months and complete several questionnaires about their health and pain levels.Inclusion Criteria
Exclusion Criteria
Timeline
Screening
Participants are screened for eligibility to participate in the trial
Treatment
Participants receive injection treatments with 5% dextrose added to local anesthetics every two weeks for a total of six visits
Follow-up
Participants are monitored for safety and effectiveness after treatment, with assessments including PHQ-9, VAS, PGIC, and BPI
Treatment Details
Interventions
- Addition of 5% Dextrose to Local Anesthetic
Find a Clinic Near You
Who Is Running the Clinical Trial?
The Seekers Centre
Lead Sponsor