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Cold Pressor Test for Stress Effects on Learning

N/A

Recruiting

Led By Elizabeth V Goldfarb, PhD

Research Sponsored by Yale University

Eligibility Criteria Checklist

Specific guidelines that determine who can or cannot participate in a clinical trial

Must have

Be between 18 and 65 years old

Timeline

Screening 3 weeks

Treatment Varies

Follow Up 1-2 hours

Awards & highlights

Study Summary

This trial looks at how stress affects how we learn and remember things.

Who is the study for?

This trial is for individuals aged 18-45 who are fluent in English and have a Body Mass Index (BMI) between 18 and 35. The study aims to understand how stress affects learning and memory.Check my eligibility

What is being tested?

The study examines the effects of acute stress on learning by using a Socially Evaluated Cold Pressor Test, where participants place their hand in cold water under social evaluation, compared to a control scenario without this stress test.See study design

What are the potential side effects?

There may be temporary discomfort from placing the hand in cold water during the Socially Evaluated Cold Pressor Test, as well as possible short-term emotional distress due to being evaluated socially.

Timeline

Screening ~ 3 weeks3 visits

Treatment ~ Varies

Follow Up ~ 1-2 hours

Screening ~ 3 weeks

Treatment ~ Varies

Follow Up ~1-2 hours

This trial's timeline: 3 weeks for screening, Varies for treatment, and 1-2 hours for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.

Primary outcome measures

Changes in fMRI signal

Episodic memory

Retention of statistical learning

+1 more

Secondary outcome measures

Alpha-amylase reactivity

Cortisol reactivity

Trial Design

2Treatment groups

Experimental Treatment

Active Control

Group I: Acute StressExperimental Treatment1 Intervention

Participants complete the socially evaluated cold pressor test (SECPT), a validated laboratory-based stress induction procedure involving submerging an arm in an ice bath

Group II: No StressActive Control1 Intervention

Participants complete a matched condition with no stress-related exposure involving submerging an arm in warm water

Do I qualify?Apply below to find out

Find a Location

Who is running the clinical trial?

National Institute of Mental Health (NIMH)NIH

2,786 Previous Clinical Trials

2,689,609 Total Patients Enrolled

Yale UniversityLead Sponsor

1,853 Previous Clinical Trials

2,738,461 Total Patients Enrolled

Elizabeth V Goldfarb, PhDPrincipal InvestigatorYale University

1 Previous Clinical Trials

27 Total Patients Enrolled

Media Library

Acute Stress 2023 Treatment Timeline for Medical Study. Trial Name: NCT05920161 — N/A

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Which is the uppermost limit of individuals enrolled in this clinical experiment?

"Affirmative. Clinicaltrials.gov displays that this investigation is presently enlisting patients, first posted on March 2nd 2023 and most recently modified on June 26th of the same year. The trial requires 100 participants to be inducted at a single site."

Answered by AI

Does this research endeavor permit individuals who are aged 35 and over to take part?

"Patients aged 18 to 45 are eligible for this medical trial, while a separate study is conducted on minors and another one for seniors over 65. The latter two trials have 24 and 110 participants respectively."

Answered by AI

What criteria must potential participants fulfill to qualify for this research study?

"In order to meet the criteria for this study, applicants must demonstrate competent spatial learning and be between 18-45 years of age. Notably, they are seeking 100 participants in total."

Answered by AI

Are there any available slots to join this clinical research project?

"According to the clinicaltrials.gov, enrollment for this trial is currently open. It was initially advertised on March 2nd 2023 and most recently updated on June 26th 2023."

Answered by AI

Recent research and studies

clinicaltrials.govStudy

Influence of Stress on Encoding and Prediction

2023. "Influence of Stress on Encoding and Prediction". ClinicalTrials.gov. https://clinicaltrials.gov/ct2/show/NCT05920161.

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