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Behavioural Intervention

Transcranial Stimulation for Memory Loss (GWI HDtDCS Trial)

N/A

Recruiting

Led By John Hart, Jr, MD

Research Sponsored by The University of Texas at Dallas

Eligibility Criteria Checklist

Specific guidelines that determine who can or cannot participate in a clinical trial

Must have

Between the ages of 18 and 50 years old DURING SERVICE in the Gulf War (born between 1940 and 1973)

Be older than 18 years old

Timeline

Screening 3 weeks

Treatment Varies

Follow Up beginning of hd tdcs/sham treatment, after hdtdcs/sham (2 weeks), at 3 month follow-up and 6 month follow-up

Awards & highlights

GWI HDtDCS Trial Summary

This trial is testing a non-invasive, non-pharmacological treatment using electric current to stimulate specific brain regions in order to improve word retrieval in Gulf War Illnesses patients.

Who is the study for?

This trial is for US Gulf War veterans who served between 1990-1991, are right-handed, and were aged 18-50 during service. Participants must understand English and be able to consent. Excluded are those with neurological disorders, severe TBI, drug abuse history, certain medication use, pacemakers or metal in the head.Check my eligibility

What is being tested?

The study tests High Definition transcranial Direct Current Stimulation (HD tDCS) on brain regions linked to word retrieval in Gulf War Illness patients. It compares active HD tDCS against a sham (inactive) treatment over ten sessions to see if it improves verbal abilities.See study design

What are the potential side effects?

While the investigators expect few side effects from HD tDCS treatment aimed at improving conversational abilities in GWI veterans, potential mild side effects might include discomfort at the stimulation site or temporary headaches.

GWI HDtDCS Trial Eligibility Criteria

Inclusion Criteria

You may be eligible if you check “Yes” for the criteria below

Select...

I served in the Gulf War and was between 18 and 50 years old at that time.

GWI HDtDCS Trial Timeline

Screening ~ 3 weeks3 visits

Treatment ~ Varies

Follow Up ~ beginning of hd tdcs/sham treatment, after hdtdcs/sham (2 weeks), at 3 month follow-up and 6 month follow-up

Screening ~ 3 weeks

Treatment ~ Varies

Follow Up ~beginning of hd tdcs/sham treatment, after hdtdcs/sham (2 weeks), at 3 month follow-up and 6 month follow-up

This trial's timeline: 3 weeks for screening, Varies for treatment, and beginning of hd tdcs/sham treatment, after hdtdcs/sham (2 weeks), at 3 month follow-up and 6 month follow-up for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.

Primary outcome measures

Change in performance on the Controlled Oral Word Association Test (COWAT)

Change in the performance on the California Verbal Learning Test (CVLT)

Secondary outcome measures

Change in the performance on the Event Related Potential (ERP)

Change in the performance on the Semantic Object Retrieval Test (SORT)

Change in the performance on the Semantic Selection Task

GWI HDtDCS Trial Design

2Treatment groups

Active Control

Placebo Group

Group I: Active HD tDCSActive Control1 Intervention

Administer 10 20-minute sessions of 1 mA anodal High Definition Transcranial Direct Current Stimulation to the preSMA region over a two week period.

Group II: Sham HD tDCSPlacebo Group1 Intervention

Administer 10 20-minute sessions of sham High Definition Transcranial Direct Current Stimulation to the preSMA region over a two week period.

0 / 1Eligibility criteria met

Find a Location

Who is running the clinical trial?

The University of Texas at DallasLead Sponsor

58 Previous Clinical Trials

106,115 Total Patients Enrolled

University of Texas Southwestern Medical CenterOTHER

1,048 Previous Clinical Trials

1,053,615 Total Patients Enrolled

John Hart, Jr, MDPrincipal InvestigatorThe University of Texas at Dallas

1 Previous Clinical Trials

80 Total Patients Enrolled

Media Library

High Definition Transcranial Direct Current Stimulation (Behavioural Intervention) Clinical Trial Eligibility Overview. Trial Name: NCT03542383 — N/A

Memory Loss Research Study Groups: Active HD tDCS, Sham HD tDCS

Memory Loss Clinical Trial 2023: High Definition Transcranial Direct Current Stimulation Highlights & Side Effects. Trial Name: NCT03542383 — N/A

High Definition Transcranial Direct Current Stimulation (Behavioural Intervention) 2023 Treatment Timeline for Medical Study. Trial Name: NCT03542383 — N/A

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Is it possible for me to be a part of this medical experiment?

"Patients that meet the criteria of memory loss between 45 and 78 years old can apply for this study, with a recruitment goal of 120 subjects."

Answered by AI

Does this clinical trial apply to individuals aged 20 or older?

"To apply for this clinical trial, individuals must range 45 to 78 years old. Additionally, there are 7 trials available for those under 18 and 31 studies that focus on patients 65 or older."

Answered by AI

What is the scale of this therapeutic trial?

"Affirmative. Information hosted on clinicaltrials.gov suggests that this medical trial is actively enrolling individuals, which commenced its initial advertisement on February 1st 2017 and was last amended October 31st 2022. The study requires 120 participants from a single facility to be recruited for the experiment."

Answered by AI

Could potential participants join this clinical research at the present time?

"The clinical trial is currently open for recruitment, as indicated on the website. This experiment was made public first on February 1st 2017 and had its most recent update at October 31st 2022."

Answered by AI

Recent research and studies

clinicaltrials.govStudy

Treatment of Memory Disorders in Gulf War Illness With High Definition Transcranial Direct Cortical Stimulation

John Hart, Jr. 2017. "Treatment of Memory Disorders in Gulf War Illness With High Definition Transcranial Direct Cortical Stimulation". ClinicalTrials.gov. https://clinicaltrials.gov/ct2/show/NCT03542383.

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