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Brain Stimulation
Home-Based Brain Stimulation for Memory Loss (MemStim-home Trial)
N/A
Waitlist Available
Led By Alvaro Pascual-Leone, Dr.
Research Sponsored by Hebrew SeniorLife
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial Must have
Be older than 18 years old
Timeline
Screening 3 weeks
Treatment Varies
Follow Up 48 weeks
Awards & highlights
MemStim-home Trial Summary
This trial will test if a remote, caregiver-led tACS can help improve memory decline in older adults.
Who is the study for?
This trial is for older adults with memory issues who can read, write, and communicate in English. They must be able to give informed consent and follow study requirements. A helper aged 21+ with computer skills and weekday availability is needed. Excluded are those with major psychiatric disorders, certain disabilities, or contraindications to brain stimulation.Check my eligibility
What is being tested?
The study tests if a home-based brain stimulation technique called tACS can help improve memory when administered by caregivers. It's designed to see how practical it is for participants and their helpers to use this technology remotely.See study design
What are the potential side effects?
Potential side effects of tACS may include discomfort at the electrode sites on the scalp, headache, fatigue or dizziness during or after treatment sessions. Serious side effects are rare but could involve changes in mood or thinking.
MemStim-home Trial Timeline
Screening ~ 3 weeks3 visits
Treatment ~ Varies
Follow Up ~ 48 weeks
Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~48 weeks
Treatment Details
Study Objectives
Outcome measures can provide a clearer picture of what you can expect from a treatment.Primary outcome measures
Clinical Evaluation and Cognitive Assessment
Electroencephalography (EEG) measures
MemStim-home Trial Design
1Treatment groups
Experimental Treatment
Group I: Transcranial alternating current stimulation (tACS)Experimental Treatment1 Intervention
Participants (Ps) will undergo 20min of daily home-based tACS intervention at 40Hz over the left angular gyrus for 4 weeks by trained administrators (As) (phase 1). In case of cognitive and mental improvement participants will undergo further 10 weeks of 20 minutes session of tACS daily (phase 2). Additionally, those P/A pairs who completed the 14 weeks of home-based tACS intervention and express an interest in an open label extension may be enrolled in further 34 weeks of 20 minutes tACS sessions.
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Who is running the clinical trial?
Hebrew SeniorLifeLead Sponsor
45 Previous Clinical Trials
270,536 Total Patients Enrolled
Alvaro Pascual-Leone, Dr.3.97 ReviewsPrincipal Investigator - Hinda and Arthur Marcus Institute for Aging Research
Hebrew SeniorLife
2 Previous Clinical Trials
39 Total Patients Enrolled
Frequently Asked Questions
These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.
Is this research currently seeking participants?
"As referenced on clinicaltrials.gov, this trial is no longer in its recruitment phase; it was initially posted on July 6th 2020 and the most recent update was published June 21st 2022. However, there are 572 other studies enrolling patients at present time."
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